PMID- 32611847
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201016
IS  - 2303-9027 (Print)
IS  - 2226-7190 (Electronic)
IS  - 2226-7190 (Linking)
VI  - 9
IP  - 4
DP  - 2020 Jul-Aug
TI  - EUS-guided through-the-needle microbiopsy of pancreatic cysts: Technical aspects 
      (with video).
PG  - 220-224
LID - 10.4103/eus.eus_12_20 [doi]
AB  - Pancreatic cystic lesions are frequently encountered and diagnostically 
      challenging as some of the cysts may have malignant potential (mucinous) while 
      others are completely benign (serous). EUS-guided through-the-needle biopsy 
      (EUS-TTNB) of the cyst wall has recently been introduced as an alternative to 
      cyst fluid cytology. Several studies have shown that microbiopsies outperform 
      cytology in terms of distinction between mucinous and nonmucinous lesions, but 
      also in determining the specific cyst diagnosis. However, little is known about 
      the technical aspects of tissue sampling with TTNB. Herein, we summarize our 
      experience with the procedure in a tertiary referral center and discuss 
      indications, technical aspects, and safety of the procedure. Most adverse events 
      (AEs) associated with the procedure are mild, but there is emerging evidence that 
      the rate of postprocedural pancreatitis is higher compared to standard 
      fine-needle aspiration. The added diagnostic yield should therefore be placed in 
      perspective with an increased risk of AEs. Prospective studies are warranted to 
      fully identify which patient groups could benefit from EUS-TTNB.
FAU - Kovacevic, Bojan
AU  - Kovacevic B
AD  - Gastroenterology Unit, Division of Endoscopy, Herlev and Gentofte Hospital, 
      Copenhagen University, Herlev, Denmark.
FAU - Kalaitzakis, Evangelos
AU  - Kalaitzakis E
AD  - Gastroenterology Unit, Division of Endoscopy, Herlev and Gentofte Hospital, 
      Copenhagen University, Herlev, Denmark.
FAU - Klausen, Pia
AU  - Klausen P
AD  - Gastroenterology Unit, Division of Endoscopy, Herlev and Gentofte Hospital, 
      Copenhagen University, Herlev, Denmark.
FAU - Brink, Lene
AU  - Brink L
AD  - Gastroenterology Unit, Division of Endoscopy, Herlev and Gentofte Hospital, 
      Copenhagen University, Herlev, Denmark.
FAU - Hassan, Hazem
AU  - Hassan H
AD  - Gastroenterology Unit, Division of Endoscopy, Herlev and Gentofte Hospital, 
      Copenhagen University, Herlev, Denmark.
FAU - Karstensen, John G
AU  - Karstensen JG
AD  - Gastroenterology Unit, Pancreatitis Centre East, Hvidovre Hospital, Department of 
      Clinical Medicine, Copenhagen University, Hvidovre, Denmark.
FAU - Vilmann, Peter
AU  - Vilmann P
AD  - Gastroenterology Unit, Division of Endoscopy, Herlev and Gentofte Hospital, 
      Copenhagen University, Herlev, Denmark.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - China
TA  - Endosc Ultrasound
JT  - Endoscopic ultrasound
JID - 101622292
PMC - PMC7529000
OTO - NOTNLM
OT  - EUS
OT  - intraductal papillary mucinous neoplasm
OT  - microbiopsy
OT  - pancreatic cyst
OT  - pancreatic cystic lesion
OT  - through-the-needle biopsy
COIS- None
EDAT- 2020/07/03 06:00
MHDA- 2020/07/03 06:01
PMCR- 2020/06/30
CRDT- 2020/07/03 06:00
PHST- 2020/07/03 06:00 [pubmed]
PHST- 2020/07/03 06:01 [medline]
PHST- 2020/07/03 06:00 [entrez]
PHST- 2020/06/30 00:00 [pmc-release]
AID - 288212 [pii]
AID - EUS-9-220 [pii]
AID - 10.4103/eus.eus_12_20 [doi]
PST - ppublish
SO  - Endosc Ultrasound. 2020 Jul-Aug;9(4):220-224. doi: 10.4103/eus.eus_12_20.