PMID- 32612350
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220415
IS  - 1177-5467 (Print)
IS  - 1177-5483 (Electronic)
IS  - 1177-5467 (Linking)
VI  - 14
DP  - 2020
TI  - Retinal Nerve Fibre Layer Thickness Change After CO2 Laser-Assisted Deep 
      Sclerectomy Surgery.
PG  - 1749-1757
LID - 10.2147/OPTH.S247595 [doi]
AB  - PURPOSE: The goal of our study was to investigate changes in intraocular pressure 
      (IOP), best-corrected visual acuity (BCVA), and retinal nerve fibre layer 
      thickness (RNFLT) after CO2 laser-assisted deep sclerectomy (CLASS). METHODS: We 
      carried out uncomplicated CLASS surgeries and a 12-month follow-up on 22 
      open-angle glaucomatous (OAG) eyes of 22 patients. IOP, BCVA, and RNFLT with 
      spectral-domain optical coherence tomography (SD OCT) were recorded before and 1, 
      3, 6, 12 months after surgery. RESULTS: Mean age of patients was 68.1 years. IOP 
      decreased from preoperative 28.45+/-5.99 SD mmHg (mean+/-standard deviation) to 
      15.09+/-2.40 mmHg (p=0.00039) at 12 months after surgery. BCVA-change from 
      preoperative 0.34+/-0.38 SD (LogMAR) to 0.37+/-0.41 SD (LogMAR) was not significant 
      (p=0.2456). RNFLT-change from preoperative 60.50+/-18.15microm to 59.63+/-17.52 microm at 12 
      months postoperatively was not significant (p=0.056). Qualified success rate of 
      CLASS surgery was 72.7%, whereas complete success rate was 64% at 1 year 
      postoperatively. CONCLUSION: Successful CLASS surgery efficiently reduced IOP. At 
      postoperative 12 months, RNFLT and BCVA were not reduced significantly. There was 
      no significant glaucomatous progression after surgery encountered in respect of 
      investigated parameters.
CI  - (c) 2020 Sohajda et al.
FAU - Sohajda, Zoltan
AU  - Sohajda Z
AUID- ORCID: 0000-0002-5724-2866
AD  - University of Debrecen, Kenezy Hospital Department of Ophthalmology, Debrecen, 
      Hungary.
FAU - Szell, Noemi
AU  - Szell N
AD  - University of Debrecen, Kenezy Hospital Department of Ophthalmology, Debrecen, 
      Hungary.
FAU - Revak, Agnes
AU  - Revak A
AD  - University of Debrecen, Kenezy Hospital Department of Ophthalmology, Debrecen, 
      Hungary.
FAU - Papp, Julia
AU  - Papp J
AUID- ORCID: 0000-0003-0904-3923
AD  - University of Debrecen, Kenezy Hospital Department of Ophthalmology, Debrecen, 
      Hungary.
FAU - Toth-Molnar, Edit
AU  - Toth-Molnar E
AUID- ORCID: 0000-0001-7989-1616
AD  - University of Szeged, Department of Ophthalmology, Szent-Gyorgyi Medical and 
      Pharmaceutical Center, Szeged, Hungary.
LA  - eng
PT  - Journal Article
DEP - 20200625
PL  - New Zealand
TA  - Clin Ophthalmol
JT  - Clinical ophthalmology (Auckland, N.Z.)
JID - 101321512
PMC - PMC7323794
OTO - NOTNLM
OT  - CLASS
OT  - best-corrected visual acuity
OT  - intraocular pressure
OT  - open-angle glaucoma
OT  - retinal nerve fiber layer thickness
COIS- None of the authors declare any conflict of interest relevant to the article.
EDAT- 2020/07/03 06:00
MHDA- 2020/07/03 06:01
PMCR- 2020/06/25
CRDT- 2020/07/03 06:00
PHST- 2020/02/08 00:00 [received]
PHST- 2020/04/23 00:00 [accepted]
PHST- 2020/07/03 06:00 [entrez]
PHST- 2020/07/03 06:00 [pubmed]
PHST- 2020/07/03 06:01 [medline]
PHST- 2020/06/25 00:00 [pmc-release]
AID - 247595 [pii]
AID - 10.2147/OPTH.S247595 [doi]
PST - epublish
SO  - Clin Ophthalmol. 2020 Jun 25;14:1749-1757. doi: 10.2147/OPTH.S247595. eCollection 
      2020.