PMID- 32617394
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231111
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 8
IP  - 7
DP  - 2020 Jul
TI  - Does a history of head and neck cancer affect outcome of endoscopic submucosal 
      dissection for superficial esophageal squamous cell carcinoma?
PG  - E900-E910
LID - 10.1055/a-1147-8977 [doi]
AB  - Background and study aims  Esophageal squamous cell carcinoma (ESCC) is the most 
      common secondary tumor in patients with head and neck squamous cell cancer 
      (HNSCC). Currently, endoscopic submucosal dissection (ESD) is the preferred 
      approach to manage superficial ESCC, however, it remains to be elucidated whether 
      patients with HNSCC and early ESCC managed by ESD have different outcomes. 
      Patients and methods  We retrospectively analyzed esophageal ESD for early ESCC 
      from September 2009 to September 2017 and the following variables: demographics, 
      tumor and specimen size, Paris classification, location, en bloc and R0 resection 
      rates, overall survival (OS) and adverse events (AEs). To reduce selection bias, 
      propensity score matching was applied to compare the results. Results  
      Eighty-nine ESDs were performed in 81 consecutive patients (47 with HNSCC and 34 
      without HNSCC). Patients with HNSCC who developed superficial ESCC were found to 
      be younger and to refer a more frequent history of alcohol ingestion and smoking. 
      There was no difference in lesion size, number of lesions, procedure time, en 
      bloc resection rate, R0 resection rate, local recurrence and adverse event rate 
      between the two groups. The histological depth of invasion for patients with 
      HNSCC was significantly shallower before ( P  = 0.016) and after ( P  = 0.047) 
      matching. The overall survival rate was similar in both groups. Conclusions  
      Patients with HNSCC have earlier detection of ESCC, probably due to endoscopic 
      screening. Previous history of chemoradiation and surgery for HNSCC does not 
      affect procedure time, AEs and OS.
FAU - Moura, Renata Nobre
AU  - Moura RN
AD  - Department of Gastroenterology, Cancer Institute, Hospital das Clinicas of 
      University of Sao Paulo, Sao Paulo, Brazil.
FAU - Arantes, Vitor Nunes
AU  - Arantes VN
AD  - Alfa Institute of Gastroenterology, Hospital de Clinicas, Federal University of 
      Minas Gerais, Belo Horizonte, Brazil.
FAU - Ribeiro, Tarso Magno Leite
AU  - Ribeiro TML
AD  - Alfa Institute of Gastroenterology, Hospital de Clinicas, Federal University of 
      Minas Gerais, Belo Horizonte, Brazil.
FAU - Guimaraes, Roberto Gardone
AU  - Guimaraes RG
AD  - Alfa Institute of Gastroenterology, Hospital de Clinicas, Federal University of 
      Minas Gerais, Belo Horizonte, Brazil.
FAU - de Oliveira, Joel Fernandez
AU  - de Oliveira JF
AD  - Department of Gastroenterology, Cancer Institute, Hospital das Clinicas of 
      University of Sao Paulo, Sao Paulo, Brazil.
FAU - Kulcsar, Marco Aurelio Vamondes
AU  - Kulcsar MAV
AD  - Department of Gastroenterology, Cancer Institute, Hospital das Clinicas of 
      University of Sao Paulo, Sao Paulo, Brazil.
FAU - Sallum, Rubens Antonio Aissar
AU  - Sallum RAA
AD  - Department of Gastroenterology, Cancer Institute, Hospital das Clinicas of 
      University of Sao Paulo, Sao Paulo, Brazil.
FAU - Ribeiro-Junior, Ulysses
AU  - Ribeiro-Junior U
AD  - Department of Gastroenterology, Cancer Institute, Hospital das Clinicas of 
      University of Sao Paulo, Sao Paulo, Brazil.
FAU - Maluf-Filho, Fauze
AU  - Maluf-Filho F
AD  - Department of Gastroenterology, Cancer Institute, Hospital das Clinicas of 
      University of Sao Paulo, Sao Paulo, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20200616
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC7297610
COIS- Competing interests The authors declare that they have no conflict of interest.
EDAT- 2020/07/04 06:00
MHDA- 2020/07/04 06:01
PMCR- 2020/07/01
CRDT- 2020/07/04 06:00
PHST- 2019/09/03 00:00 [received]
PHST- 2020/02/17 00:00 [accepted]
PHST- 2020/07/04 06:00 [entrez]
PHST- 2020/07/04 06:00 [pubmed]
PHST- 2020/07/04 06:01 [medline]
PHST- 2020/07/01 00:00 [pmc-release]
AID - 10.1055/a-1147-8977 [doi]
PST - ppublish
SO  - Endosc Int Open. 2020 Jul;8(7):E900-E910. doi: 10.1055/a-1147-8977. Epub 2020 Jun 
      16.