PMID- 32620205 OWN - NLM STAT- MEDLINE DCOM- 20200716 LR - 20200716 IS - 1769-6917 (Electronic) IS - 0007-4551 (Linking) VI - 107 IP - 5S DP - 2020 Jun TI - [Oligorecurrent prostate cancer: current management and perspectives]. PG - S35-S40 LID - S0007-4551(20)30276-9 [pii] LID - 10.1016/S0007-4551(20)30276-9 [doi] AB - Oligometastatic prostate cancer (PCa) is an intense area of research thanks to the development of novel PET tracers such as (18)F-choline or (68)Ga-PSMA. Several retrospective studies in patients with hormone-sensitive oligorecurrent PCa (usually up to 5 metastases with a controlled primary tumor) showed PSA response and a low toxicity profile of metastasis-directed therapies (MDT) such as Stereotactic Body Radiation Therapy (SBRT) or salvage lymph node dissection. More recently, randomized phase 2 studies showed that SBRT can delay the introduction of androgen deprivation, decrease biochemical relapses and increase overall survival. Regarding oligoprogressive metastatic castration-resistant PCa, limited data is however available. Based on these studies the European Association of Urology and the American Society of Radiotherapy EAU now recommend using MDT instead of observation. Several studies are undergoing in France and worldwide in order to confirm the exact role of MDT. CI - Copyright (c) 2020 Societe Francaise du Cancer. Publie par Elsevier Masson SAS. Tous droits reserves. FAU - Loubersac, Thomas AU - Loubersac T AD - Urologie, Hotel-Dieu, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes, France. FAU - Guimas, Valentine AU - Guimas V AD - Service de radiotherapie, Institut de cancerologie de l'Ouest, boulevard Professeur-Jacques-Monod, 44800 Nantes Saint-Herblain, France. FAU - Rio, Emmanuel AU - Rio E AD - Service de radiotherapie, Institut de cancerologie de l'Ouest, boulevard Professeur-Jacques-Monod, 44800 Nantes Saint-Herblain, France. FAU - Libois, Vincent AU - Libois V AD - Service de radiotherapie, Institut de cancerologie de l'Ouest, boulevard Professeur-Jacques-Monod, 44800 Nantes Saint-Herblain, France. FAU - Rigaud, Jerome AU - Rigaud J AD - Urologie, Hotel-Dieu, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes, France. FAU - Supiot, Stephane AU - Supiot S AD - Service de radiotherapie, Institut de cancerologie de l'Ouest, boulevard Professeur-Jacques-Monod, 44800 Nantes Saint-Herblain, France. Electronic address: stephane.supiot@ico.unicancer.fr. LA - fre PT - Journal Article PT - Review TT - Prise en charge des rechutes oligometastatiques des cancers de prostate : actualites et perspectives. PL - France TA - Bull Cancer JT - Bulletin du cancer JID - 0072416 SB - IM MH - Humans MH - Male MH - Neoplasm Recurrence, Local/*therapy MH - Prostatic Neoplasms/*therapy OTO - NOTNLM OT - Cancer de prostate OT - Choline PET OT - Oligometastatic OT - Oligoprogression OT - Oligoprogressive OT - Oligorecurrent OT - Oligorecurrence OT - PSMA OT - Radiotherapie OT - SBRT OT - TEP-FCH OT - oligometastatique OT - prostate cancer OT - stereotaxique EDAT- 2020/07/06 06:00 MHDA- 2020/07/17 06:00 CRDT- 2020/07/05 06:00 PHST- 2020/07/05 06:00 [entrez] PHST- 2020/07/06 06:00 [pubmed] PHST- 2020/07/17 06:00 [medline] AID - S0007-4551(20)30276-9 [pii] AID - 10.1016/S0007-4551(20)30276-9 [doi] PST - ppublish SO - Bull Cancer. 2020 Jun;107(5S):S35-S40. doi: 10.1016/S0007-4551(20)30276-9.