PMID- 32620958 OWN - NLM STAT- MEDLINE DCOM- 20210531 LR - 20210531 IS - 1535-2900 (Electronic) IS - 1079-2082 (Linking) VI - 77 IP - 17 DP - 2020 Aug 20 TI - Novel mobile application for direct communication between pharmacists and patients treated with oral antineoplastic agents. PG - 1393-1402 LID - 10.1093/ajhp/zxaa144 [doi] AB - PURPOSE: Initial experience with use of a smartphone application to enhance communication with and home monitoring of hematology/oncology patients under treatment with oral antineoplastic agents (OAAs) is described. SUMMARY: Broad use of OAAs is changing the landscape of hematology/oncology patient care, with this form of therapy giving patients greater autonomy but also raising concerns about correct OAA administration and management of adverse effects (AEs) or interactions. Information and communication technologies, specifically mobile health technologies, are ideal tools in this new environment. A multidisciplinary team at a large hospital in Spain developed a smartphone application for patients receiving OAA therapy that consists of 5 modules or functionalities: (1) a treatment agenda, or electronic journal of patient activity, including medication use; (2) a treatment record; (3) continuous recording of vital signs (blood pressure and temperature), health-related quality of life, and AEs, with management of AEs based on an algorithm that displays different recommendations according to AE severity; (4) 2-way messaging capability; and (5) information and links to websites of interest. From June through November 2017, 37 patients downloaded and used the application. About two-thirds (68%) of the patients sent a total of 182 messages to the pharmacist on duty; 58% of the patients registered at least 1 AE. The mean time of registration of the first AE after initiation of OAA therapy was 8 days. As a result of patient use of the application, 2 emergency room visits were avoided and 3 patients were referred to a general practitioner. CONCLUSION: The application has allowed real-time monitoring of patients treated with OAAs. This new patient-pharmacist communication channel has facilitated the early detection of AEs, contributing to the safety of treatment and patient satisfaction with healthcare. CI - (c) American Society of Health-System Pharmacists 2020. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. FAU - Collado-Borrell, Roberto AU - Collado-Borrell R AD - Pharmacy Department, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), Madrid, Spain. FAU - Escudero-Vilaplana, Vicente AU - Escudero-Vilaplana V AD - Pharmacy Department, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), Madrid, Spain. FAU - Ribed, Almudena AU - Ribed A AD - Pharmacy Department, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), Madrid, Spain. FAU - Jimenez, Rosa Romero AU - Jimenez RR AD - Pharmacy Department, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), Madrid, Spain. FAU - Peinado, Irene Iglesias AU - Peinado II AD - College of Pharmacy, Complutense University of Madrid, Madrid, Spain. FAU - Herranz-Alonso, Ana AU - Herranz-Alonso A AD - Pharmacy Department, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), Madrid, Spain. FAU - Sanjurjo-Saez, Maria AU - Sanjurjo-Saez M AD - Pharmacy Department, Hospital General Universitario Gregorio Maranon, Instituto de Investigacion Sanitaria Gregorio Maranon (IiSGM), Madrid, Spain. LA - eng PT - Journal Article PL - England TA - Am J Health Syst Pharm JT - American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists JID - 9503023 RN - 0 (Antineoplastic Agents) SB - IM MH - Administration, Oral MH - Adult MH - Aged MH - Aged, 80 and over MH - Antineoplastic Agents/*administration & dosage/adverse effects MH - Communication MH - Female MH - Humans MH - Male MH - Middle Aged MH - *Mobile Applications MH - Patient Satisfaction MH - Pharmacists/*organization & administration MH - Pharmacy Service, Hospital/organization & administration MH - *Professional-Patient Relations MH - Quality of Life MH - Smartphone MH - Spain MH - Young Adult OTO - NOTNLM OT - e-OncoSalud OT - hematology/oncology patient OT - home monitoring OT - oral antineoplastic agents OT - safety OT - smartphone application EDAT- 2020/07/06 06:00 MHDA- 2021/06/01 06:00 CRDT- 2020/07/05 06:00 PHST- 2020/07/06 06:00 [pubmed] PHST- 2021/06/01 06:00 [medline] PHST- 2020/07/05 06:00 [entrez] AID - 5867286 [pii] AID - 10.1093/ajhp/zxaa144 [doi] PST - ppublish SO - Am J Health Syst Pharm. 2020 Aug 20;77(17):1393-1402. doi: 10.1093/ajhp/zxaa144.