PMID- 32622915
OWN - NLM
STAT- MEDLINE
DCOM- 20210512
LR  - 20210512
IS  - 1444-2892 (Electronic)
IS  - 1443-9506 (Linking)
VI  - 29
IP  - 12
DP  - 2020 Dec
TI  - Association of Controlling Nutritional Status Score With 2-Year Clinical Outcomes 
      in Patients With ST Elevation Myocardial Infarction Undergoing Primary 
      Percutaneous Coronary Intervention.
PG  - 1758-1765
LID - S1443-9506(20)30116-5 [pii]
LID - 10.1016/j.hlc.2020.02.017 [doi]
AB  - BACKGROUND: This study evaluated whether the Controlling Nutritional Status 
      (CONUT) score could predict clinical outcomes in ST elevation myocardial 
      infarction (STEMI) patients. METHODS: We performed a retrospective cohort study 
      of STEMI patients after primary percutaneous coronary intervention (pPCI). The 
      endpoint was major adverse cardiac event (MACE). Information was obtained from 
      medical records and via telephone calls. Patients were divided into three groups: 
      normal (CONUT score 0-1; n=278), mild-moderate (score 2-4; n=418), and severe 
      (score >/=5; n=55) groups. RESULTS: During the 24.6+/-12 months follow-up, MACEs were 
      observed in 65 (8.7%) patients. The incidence of MACEs was 6.1%, 5.5%, and 45.5% 
      in the normal, mild-moderate, and severe group, respectively (p<0.001). 
      Kaplan-Meier curves revealed that patients with a CONUT score >/=5 had the 
      significantly highest rate of MACE, myocardial re-infarction, and vessel 
      revascularisation. In three Cox proportional hazard models, the CONUT scores were 
      unexceptionally associated with MACE, even after adjusting all other variables 
      (hazard ratio, 12.09; 95% confidence interval [CI], 5.09-28.7; p<0.001). The 
      C-statistic of the CONUT score for the prediction of MACE was 0.692 (95% CI, 
      0.613-0.771; p<0.001), which is close to that of Global Registry of Acute 
      Coronary Events. CONCLUSIONS: The nutritional status evaluated by the CONUT score 
      can independently predict clinical outcomes in STEMI patients, which suggests 
      that active nutritional management is meaningful for these patients after PCI.
CI  - Copyright (c) 2020. Published by Elsevier B.V.
FAU - Deng, Xin
AU  - Deng X
AD  - Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China; 
      Shanghai Cardiovascular Medical Center, Shanghai Institute of Cardiovascular 
      Diseases; Institute of Pan-vascular Medicine, Fudan University, Shanghai, China.
FAU - Zhang, Shuning
AU  - Zhang S
AD  - Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China; 
      Shanghai Cardiovascular Medical Center, Shanghai Institute of Cardiovascular 
      Diseases; Institute of Pan-vascular Medicine, Fudan University, Shanghai, China.
FAU - Shen, Shutong
AU  - Shen S
AD  - Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China; 
      Shanghai Cardiovascular Medical Center, Shanghai Institute of Cardiovascular 
      Diseases; Institute of Pan-vascular Medicine, Fudan University, Shanghai, China.
FAU - Deng, Liyu
AU  - Deng L
AD  - Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China; 
      Shanghai Cardiovascular Medical Center, Shanghai Institute of Cardiovascular 
      Diseases; Institute of Pan-vascular Medicine, Fudan University, Shanghai, China.
FAU - Shen, Li
AU  - Shen L
AD  - Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China; 
      Shanghai Cardiovascular Medical Center, Shanghai Institute of Cardiovascular 
      Diseases; Institute of Pan-vascular Medicine, Fudan University, Shanghai, China.
FAU - Qian, Juying
AU  - Qian J
AD  - Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China; 
      Shanghai Cardiovascular Medical Center, Shanghai Institute of Cardiovascular 
      Diseases; Institute of Pan-vascular Medicine, Fudan University, Shanghai, China.
FAU - Ge, Junbo
AU  - Ge J
AD  - Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China; 
      Shanghai Cardiovascular Medical Center, Shanghai Institute of Cardiovascular 
      Diseases; Institute of Pan-vascular Medicine, Fudan University, Shanghai, China. 
      Electronic address: jbge@zs-hospital.sh.cn.
LA  - eng
PT  - Journal Article
DEP - 20200414
PL  - Australia
TA  - Heart Lung Circ
JT  - Heart, lung & circulation
JID - 100963739
SB  - IM
MH  - Aged
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Nutritional Status
MH  - *Percutaneous Coronary Intervention
MH  - Retrospective Studies
MH  - Risk Factors
MH  - ST Elevation Myocardial Infarction/*diagnosis/surgery
MH  - Time Factors
OTO - NOTNLM
OT  - Controlling nutritional status
OT  - Major adverse cardiac event
OT  - Primary percutaneous coronary intervention
OT  - ST elevation myocardial infarction
EDAT- 2020/07/06 06:00
MHDA- 2021/05/13 06:00
CRDT- 2020/07/06 06:00
PHST- 2019/11/23 00:00 [received]
PHST- 2020/01/31 00:00 [revised]
PHST- 2020/02/29 00:00 [accepted]
PHST- 2020/07/06 06:00 [pubmed]
PHST- 2021/05/13 06:00 [medline]
PHST- 2020/07/06 06:00 [entrez]
AID - S1443-9506(20)30116-5 [pii]
AID - 10.1016/j.hlc.2020.02.017 [doi]
PST - ppublish
SO  - Heart Lung Circ. 2020 Dec;29(12):1758-1765. doi: 10.1016/j.hlc.2020.02.017. Epub 
      2020 Apr 14.