PMID- 32626327
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240328
IS  - 1831-4732 (Electronic)
IS  - 1831-4732 (Linking)
VI  - 17
IP  - 5
DP  - 2019 May
TI  - Review of the existing maximum residue levels for clethodim according to Article 
      12 of Regulation (EC) No 396/2005.
PG  - e05706
LID - 10.2903/j.efsa.2019.5706 [doi]
LID - e05706
AB  - According to Article 12 of Regulation (EC) No 396/2005, EFSA has reviewed the 
      maximum residue levels (MRLs) currently established at European level for the 
      pesticide active substance clethodim. To assess the occurrence of clethodim 
      residues in plants, processed commodities, rotational crops and livestock, EFSA 
      considered the conclusions derived in the framework of Directive 91/414/EEC, the 
      MRLs established by the Codex Alimentarius Commission and European authorisations 
      reported by Member States (including the supporting residues data). Based on the 
      assessment of the available data, MRL could not be proposed because an overall 
      consumer risk assessment could not be finalised. Risk managers should be made 
      aware that the genotoxic potential of the clethodim metabolite 3-chloroallyl 
      alcohol, the aglycon of 3-chlorolallyl alcohol glucoside (M14A/M15A) could not be 
      concluded and no toxicological reference values could be derived for this 
      metabolite. Until a conclusion on the toxicological properties of the metabolite 
      is reached, a decision on the residue definition for risk assessment cannot be 
      made which is a prerequisite to perform a reliable dietary risk assessment.
CI  - (c) 2019 European Food Safety Authority. EFSA Journal published by John Wiley and 
      Sons Ltd on behalf of European Food Safety Authority.
CN  - European Food Safety Authority (EFSA)
FAU - Anastassiadou, Maria
AU  - Anastassiadou M
FAU - Brancato, Alba
AU  - Brancato A
FAU - Carrasco Cabrera, Luis
AU  - Carrasco Cabrera L
FAU - Ferreira, Lucien
AU  - Ferreira L
FAU - Greco, Luna
AU  - Greco L
FAU - Jarrah, Samira
AU  - Jarrah S
FAU - Kazocina, Aija
AU  - Kazocina A
FAU - Leuschner, Renata
AU  - Leuschner R
FAU - Magrans, Jose Oriol
AU  - Magrans JO
FAU - Miron, Ileana
AU  - Miron I
FAU - Pedersen, Ragnor
AU  - Pedersen R
FAU - Raczyk, Marianna
AU  - Raczyk M
FAU - Reich, Hermine
AU  - Reich H
FAU - Ruocco, Silvia
AU  - Ruocco S
FAU - Sacchi, Angela
AU  - Sacchi A
FAU - Santos, Miguel
AU  - Santos M
FAU - Stanek, Alois
AU  - Stanek A
FAU - Tarazona, Jose
AU  - Tarazona J
FAU - Theobald, Anne
AU  - Theobald A
FAU - Verani, Alessia
AU  - Verani A
LA  - eng
PT  - Journal Article
DEP - 20190522
PL  - United States
TA  - EFSA J
JT  - EFSA journal. European Food Safety Authority
JID - 101642076
PMC - PMC7009186
OTO - NOTNLM
OT  - 3-chloroallyl alcohol glucoside
OT  - MRL review
OT  - Regulation (EC) No 396/2005
OT  - clethodim
OT  - consumer risk assessment
OT  - cyclohexene oxime
OT  - herbicide
EDAT- 2019/05/22 00:00
MHDA- 2019/05/22 00:01
PMCR- 2019/05/22
CRDT- 2020/07/07 06:00
PHST- 2020/07/07 06:00 [entrez]
PHST- 2019/05/22 00:00 [pubmed]
PHST- 2019/05/22 00:01 [medline]
PHST- 2019/05/22 00:00 [pmc-release]
AID - EFS25706 [pii]
AID - 10.2903/j.efsa.2019.5706 [doi]
PST - epublish
SO  - EFSA J. 2019 May 22;17(5):e05706. doi: 10.2903/j.efsa.2019.5706. eCollection 2019 
      May.