PMID- 3262954
OWN - NLM
STAT- MEDLINE
DCOM- 19881122
LR  - 20181113
IS  - 0044-0086 (Print)
IS  - 1551-4056 (Electronic)
IS  - 0044-0086 (Linking)
VI  - 61
IP  - 3
DP  - 1988 May-Jun
TI  - Human T-cell lymphotropic virus type I and adult T-cell leukemia/lymphoma outside 
      Japan and the Caribbean Basin.
PG  - 215-22
AB  - Ninety-six patients with the diagnosis of adult T-cell leukemia/lymphoma (ATLL) 
      were identified in countries outside Japan and the Caribbean Basin. Seventy-four 
      of these patients were initially diagnosed in the United States; 25 of 52 
      patients whose places of birth were known had been born in the United States. The 
      detection of 14 patients born in the southeastern United States, all black, 
      indicates a group deserving particular attention for studies of human T-cell 
      lymphotropic virus type I (HTLV-I), a suspected etiologic agent in most cases of 
      ATLL. Although geographic clustering of ATLL in areas endemic for HTLV-I, 
      particularly southwest Japan and the Caribbean Basin, is a dramatic feature of 
      this disease, a review of the literature indicates that HTLV-I-associated ATLL 
      probably occurs sporadically in a much wider distribution, the disease being 
      diagnosed in native-born African, Chinese, European, and Latin American patients. 
      A registry for ATLL cases is suggested, to assist in the identification of risk 
      factors for this disease and, at the same time, improve case definitions and 
      early diagnosis.
FAU - Levine, P H
AU  - Levine PH
AD  - Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 
      20892.
FAU - Jaffe, E S
AU  - Jaffe ES
FAU - Manns, A
AU  - Manns A
FAU - Murphy, E L
AU  - Murphy EL
FAU - Clark, J
AU  - Clark J
FAU - Blattner, W A
AU  - Blattner WA
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Yale J Biol Med
JT  - The Yale journal of biology and medicine
JID - 0417414
RN  - 0 (HTLV-I Antibodies)
SB  - IM
MH  - Adult
MH  - Aged
MH  - *Cross-Cultural Comparison
MH  - Cross-Sectional Studies
MH  - Female
MH  - HTLV-I Antibodies/*analysis
MH  - Human T-lymphotropic virus 1/*immunology
MH  - Humans
MH  - Leukemia-Lymphoma, Adult T-Cell/diagnosis/*epidemiology/immunology
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - United States
PMC - PMC2590467
EDAT- 1988/05/01 00:00
MHDA- 1988/05/01 00:01
PMCR- 1988/05/01
CRDT- 1988/05/01 00:00
PHST- 1988/05/01 00:00 [pubmed]
PHST- 1988/05/01 00:01 [medline]
PHST- 1988/05/01 00:00 [entrez]
PHST- 1988/05/01 00:00 [pmc-release]
PST - ppublish
SO  - Yale J Biol Med. 1988 May-Jun;61(3):215-22.