PMID- 32632552
OWN - NLM
STAT- MEDLINE
DCOM- 20210616
LR  - 20210616
IS  - 1615-2573 (Electronic)
IS  - 0910-8327 (Linking)
VI  - 36
IP  - 1
DP  - 2021 Jan
TI  - Noninvasive assessment of intraventricular pressure difference in left 
      ventricular dyssynchrony using vector flow mapping.
PG  - 92-98
LID - 10.1007/s00380-020-01664-3 [doi]
AB  - Diastolic intraventricular pressure difference (IVPD) reflects left ventricular 
      (LV) diastolic function. The relative pressure imaging (RPI) enables the 
      noninvasive quantification of IVPD based on vector flow mapping (VFM) and 
      visualization of regional pressure distribution. LV dyssynchrony causes 
      deterioration of cardiac performance. However, it remains unclear how IVPD is 
      modulated by LV dyssynchrony. LV dyssynchrony was created in ten open-chest dogs 
      by right ventricular (RV) pacing. The other ten dogs undergoing right atrial (RA) 
      pacing set at the similar heart rate with RV pacing were used as controls. 
      Echocardiographic images were acquired at baseline and during pacing 
      simultaneously with LV pressure measurement by a micromanometer. Pressure 
      difference (DeltaP) was computed between the apex and the base of the LV inflow tract 
      during a cardiac cycle by RPI and DeltaP during isovolumic relaxation time (DeltaP(IRT)), 
      a parameter of diastolic suction, and that during early filling phase (DeltaP(E)) 
      were measured. During RV pacing, stroke volume (SV) and DeltaP(IRT) decreased 
      significantly, while DeltaP(E) did not change compared to the baseline. During RA 
      pacing, SV, DeltaP(IRT) and DeltaP(E) did not change significantly. DeltaP(IRT) tended to 
      correlate with -dP/dt(min) and end-systolic volume, and significantly correlated 
      with ejection fraction. IVPD during isovolumic relaxation time was decreased by 
      LV dyssynchrony, while IVPD during early filling phase was not. A reduction of 
      diastolic suction is observed in LV dyssynchrony and is significantly related to 
      a decrease in SV.
FAU - Minami, Seina
AU  - Minami S
AD  - Division of Functional Diagnostics, Department of Health Sciences, Osaka 
      University Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka, 565-0871, 
      Japan.
FAU - Masuda, Kasumi
AU  - Masuda K
AD  - Division of Functional Diagnostics, Department of Health Sciences, Osaka 
      University Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka, 565-0871, 
      Japan.
FAU - Stugaard, Marie
AU  - Stugaard M
AD  - Division of Functional Diagnostics, Department of Health Sciences, Osaka 
      University Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka, 565-0871, 
      Japan.
FAU - Kamimukai, Toshiki
AU  - Kamimukai T
AD  - Division of Functional Diagnostics, Department of Health Sciences, Osaka 
      University Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka, 565-0871, 
      Japan.
FAU - Asanuma, Toshihiko
AU  - Asanuma T
AD  - Division of Functional Diagnostics, Department of Health Sciences, Osaka 
      University Graduate School of Medicine, 1-7 Yamadaoka, Suita, Osaka, 565-0871, 
      Japan.
FAU - Nakatani, Satoshi
AU  - Nakatani S
AUID- ORCID: 0000-0002-8709-8615
AD  - Saiseikai Senri Hospital, 1-1-6 Tsukumodai, Suita, Osaka, 565-0862, Japan. 
      snakatani@senri.saiseikai.or.jp.
LA  - eng
PT  - Journal Article
DEP - 20200706
PL  - Japan
TA  - Heart Vessels
JT  - Heart and vessels
JID - 8511258
SB  - IM
MH  - Animals
MH  - Blood Flow Velocity/*physiology
MH  - Diastole
MH  - Disease Models, Animal
MH  - Dogs
MH  - Echocardiography
MH  - Female
MH  - Heart Rate/physiology
MH  - Heart Ventricles/diagnostic imaging/*physiopathology
MH  - Myocardial Contraction/*physiology
MH  - Stroke Volume/physiology
MH  - Ventricular Dysfunction, Left/diagnosis/*physiopathology
MH  - Ventricular Function, Left/*physiology
MH  - Ventricular Function, Right/*physiology
MH  - Ventricular Pressure/*physiology
OTO - NOTNLM
OT  - Diastolic function
OT  - Intraventricular pressure difference
OT  - Left ventricular dyssynchrony
OT  - Vector flow mapping
EDAT- 2020/07/08 06:00
MHDA- 2021/06/17 06:00
CRDT- 2020/07/08 06:00
PHST- 2020/04/17 00:00 [received]
PHST- 2020/07/03 00:00 [accepted]
PHST- 2020/07/08 06:00 [pubmed]
PHST- 2021/06/17 06:00 [medline]
PHST- 2020/07/08 06:00 [entrez]
AID - 10.1007/s00380-020-01664-3 [pii]
AID - 10.1007/s00380-020-01664-3 [doi]
PST - ppublish
SO  - Heart Vessels. 2021 Jan;36(1):92-98. doi: 10.1007/s00380-020-01664-3. Epub 2020 
      Jul 6.