PMID- 32633025
OWN - NLM
STAT- MEDLINE
DCOM- 20210621
LR  - 20210621
IS  - 1447-0756 (Electronic)
IS  - 1341-8076 (Linking)
VI  - 46
IP  - 9
DP  - 2020 Sep
TI  - Uterine fibroids and preterm birth risk: A systematic review and meta-analysis.
PG  - 1711-1727
LID - 10.1111/jog.14343 [doi]
AB  - AIM: This study explored the association between the presence of uterine fibroids 
      (UF), as determined by ultrasound, and preterm birth (PB) risk. METHODS: Medline, 
      Embase, Cochrane, Scopus and Web of Science databases. Studies reporting women 
      with and without UF demonstrated by an ultrasound exam. The primary outcome was 
      the risk of PB < 37 weeks of gestation in pregnancies with UF diagnosed by an 
      obstetric ultrasound exam. Effects for dichotomous and continuous outcomes are, 
      respectively, reported as risk ratios (RR) or mean differences and their 95% 
      confidence intervals (CI). RESULTS: Eighteen studies were included comprising 
      276 172 pregnancies to whom obstetric ultrasound assessment was performed for the 
      presence/absence of UF. Women with UF were older (mean difference = 2.40 years, 
      95% CI 0.94-3.85) and were at higher risk of PB before 37 (RR = 1.43, 95% CI 
      1.27-1.60), 34 (RR = 1.79, 95% CI 1.32-2.42), 32 (RR = 1.94, 95% CI 1.33-2.85) 
      and 28 (RR = 2.17, 95% CI 1.48-3.17) weeks as compared to those without UF (P 
      < 0.01). In addition, women with UF were at higher risk of threatened preterm 
      labor, preterm premature rupture of membranes, fetal malpresentation, placental 
      abruption, lower gestational age and birthweight at delivery and a higher 
      cesarean delivery rate. CONCLUSION: Pregnant women with UF are at increased risk 
      of PB and other adverse obstetric outcomes.
CI  - (c) 2020 Japan Society of Obstetrics and Gynecology.
FAU - Perez-Roncero, Gonzalo R
AU  - Perez-Roncero GR
AD  - Red de Investigacion de Ginecologia, Obstetricia y Reproduccion, Instituto de 
      Investigaciones Sanitarias de Aragon, Zaragoza, Spain.
FAU - Lopez-Baena, Maria T
AU  - Lopez-Baena MT
AD  - Red de Investigacion de Ginecologia, Obstetricia y Reproduccion, Instituto de 
      Investigaciones Sanitarias de Aragon, Zaragoza, Spain.
FAU - Ornat, Lia
AU  - Ornat L
AD  - Red de Investigacion de Ginecologia, Obstetricia y Reproduccion, Instituto de 
      Investigaciones Sanitarias de Aragon, Zaragoza, Spain.
AD  - Department of Obstetrics and Gynecology, University of Zaragoza Faculty of 
      Medicine, Zaragoza, Spain.
FAU - Cuerva, Marcos J
AU  - Cuerva MJ
AD  - Department of Obstetrics and Gynecology, Hospital Universitario La Paz, Madrid, 
      Spain.
FAU - Garcia-Casarrubios, Patricia
AU  - Garcia-Casarrubios P
AD  - Department of Obstetrics and Gynecology, Hospital Universitario La Paz, Madrid, 
      Spain.
FAU - Chedraui, Peter
AU  - Chedraui P
AD  - Instituto de Investigacion e Innovacion en Salud Integral, Facultad de Ciencias 
      Medicas, Universidad Catolica de Santiago de Guayaquil, Guayaquil, Ecuador.
AD  - Facultad de Ciencias de la Salud, Universidad Catolica Nuestra Senora de la, 
      Asuncion, Paraguay.
FAU - Perez-Lopez, Faustino R
AU  - Perez-Lopez FR
AD  - Red de Investigacion de Ginecologia, Obstetricia y Reproduccion, Instituto de 
      Investigaciones Sanitarias de Aragon, Zaragoza, Spain.
AD  - Department of Obstetrics and Gynecology, University of Zaragoza Faculty of 
      Medicine, Zaragoza, Spain.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20200706
PL  - Australia
TA  - J Obstet Gynaecol Res
JT  - The journal of obstetrics and gynaecology research
JID - 9612761
SB  - IM
MH  - Female
MH  - Gestational Age
MH  - Humans
MH  - Infant, Newborn
MH  - *Leiomyoma/diagnostic imaging/epidemiology
MH  - *Obstetric Labor, Premature
MH  - Placenta
MH  - Pregnancy
MH  - *Premature Birth/epidemiology/etiology
OTO - NOTNLM
OT  - birthweight
OT  - preterm birth
OT  - preterm delivery
OT  - ultrasound diagnosis
OT  - uterine fibroids
OT  - uterine myomas
EDAT- 2020/07/08 06:00
MHDA- 2021/06/22 06:00
CRDT- 2020/07/08 06:00
PHST- 2020/01/06 00:00 [received]
PHST- 2020/04/21 00:00 [revised]
PHST- 2020/05/16 00:00 [accepted]
PHST- 2020/07/08 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2020/07/08 06:00 [entrez]
AID - 10.1111/jog.14343 [doi]
PST - ppublish
SO  - J Obstet Gynaecol Res. 2020 Sep;46(9):1711-1727. doi: 10.1111/jog.14343. Epub 
      2020 Jul 6.