PMID- 32637204
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220415
IS  - 2229-5097 (Print)
IS  - 2152-7806 (Electronic)
IS  - 2152-7806 (Linking)
VI  - 11
DP  - 2020
TI  - Isolated neuroparacoccidioidomycosis as a pseudotumoral lesion in the absence of 
      systemic disease.
PG  - 151
LID - 10.25259/SNI_224_2020 [doi]
LID - 151
AB  - BACKGROUND: Paracoccidioidomycosis (PCM) is a systemic, progressive, 
      noncontagious, and often chronic disease caused by the fungus Paracoccidioides 
      brasiliensis that rarely affects the central nervous system (CNS). The condition 
      is usually treated using antifungal drugs, and some cases may require surgery. 
      CASE DESCRIPTION: A 55-year-old man, a smoker, without known comorbidities, was 
      referred to the neurosurgery team with a history of a single epileptic seizure a 
      week before hospital admission followed by progressive right- sided hemiparesis. 
      Head computed tomography and brain magnetic resonance imaging showed an 
      intra-axial expansive lesion affecting the left parietal lobe, associated with 
      extensive edema and a regional compressive effect producing slight subfalcine 
      herniation that was initially managed as an abscess. After the failure of 
      antibiotic treatment, the patient underwent a neurosurgical procedure for 
      excision of the lesion. Histopathological analysis revealed that it was PCM and 
      there was no evidence of impairment of other systems due to the disease. 
      CONCLUSION: PCM can be a serious, debilitating disease and is potentially fatal. 
      Although isolated CNS involvement is rare, it must be considered, especially in 
      endemic areas, as late diagnosis and treatment severely decreases good outcome 
      rates.
CI  - Copyright: (c) 2020 Surgical Neurology International.
FAU - Riechelmann, Ricardo Salemi
AU  - Riechelmann RS
AD  - Department of Surgery, Santa Casa de Sao Paulo School of Medical Sciences, Rua 
      Dr. Cesario Motta Junior, Sao Paulo, Brazil.
FAU - Rodrigues, Leonardo Henrique
AU  - Rodrigues LH
AD  - Department of Surgery, Santa Casa de Sao Paulo School of Medical Sciences, Rua 
      Dr. Cesario Motta Junior, Sao Paulo, Brazil.
FAU - Avelar, Tiago Marques
AU  - Avelar TM
AD  - Department of Surgery, Santa Casa de Sao Paulo School of Medical Sciences, Rua 
      Dr. Cesario Motta Junior, Sao Paulo, Brazil.
FAU - Xander, Paulo Adolfo
AU  - Xander PA
AD  - Department of Surgery, Santa Casa de Sao Paulo School of Medical Sciences, Rua 
      Dr. Cesario Motta Junior, Sao Paulo, Brazil.
FAU - da Costa, Guilherme Henrique
AU  - da Costa GH
AD  - Department of Surgery, Santa Casa de Sao Paulo School of Medical Sciences, Rua 
      Dr. Cesario Motta Junior, Sao Paulo, Brazil.
FAU - Cannoni, Luiz Fernando
AU  - Cannoni LF
AD  - Department of Surgery, Santa Casa de Sao Paulo School of Medical Sciences, Rua 
      Dr. Cesario Motta Junior, Sao Paulo, Brazil.
FAU - de Aguiar, Guilherme Brasileiro
AU  - de Aguiar GB
AD  - Department of Surgery, Santa Casa de Sao Paulo School of Medical Sciences, Rua 
      Dr. Cesario Motta Junior, Sao Paulo, Brazil.
FAU - Veiga, Jose Carlos
AU  - Veiga JC
AD  - Department of Surgery, Santa Casa de Sao Paulo School of Medical Sciences, Rua 
      Dr. Cesario Motta Junior, Sao Paulo, Brazil.
LA  - eng
PT  - Case Reports
DEP - 20200613
PL  - United States
TA  - Surg Neurol Int
JT  - Surgical neurology international
JID - 101535836
PMC - PMC7332495
OTO - NOTNLM
OT  - Central nervous system infections
OT  - Neurosurgical procedures
OT  - Paracoccidioidomycosis
COIS- There are no conflicts of interest.
EDAT- 2020/07/09 06:00
MHDA- 2020/07/09 06:01
PMCR- 2020/06/13
CRDT- 2020/07/09 06:00
PHST- 2020/04/27 00:00 [received]
PHST- 2020/05/23 00:00 [accepted]
PHST- 2020/07/09 06:00 [entrez]
PHST- 2020/07/09 06:00 [pubmed]
PHST- 2020/07/09 06:01 [medline]
PHST- 2020/06/13 00:00 [pmc-release]
AID - SNI-11-151 [pii]
AID - 10.25259/SNI_224_2020 [doi]
PST - epublish
SO  - Surg Neurol Int. 2020 Jun 13;11:151. doi: 10.25259/SNI_224_2020. eCollection 
      2020.