PMID- 32638085
OWN - NLM
STAT- MEDLINE
DCOM- 20210224
LR  - 20210224
IS  - 1434-4726 (Electronic)
IS  - 0937-4477 (Linking)
VI  - 278
IP  - 1
DP  - 2021 Jan
TI  - Prognostic nomogram based on immune scores for laryngeal squamous cell cancer.
PG  - 141-148
LID - 10.1007/s00405-020-06189-z [doi]
AB  - PURPOSE: Immune scores have been used as a prognostic factor for various types of 
      cancer. However, the association between immune scores and the prognosis of 
      laryngeal squamous cell cancer (LSCC) has not yet been investigated. This study 
      aimed to explore the prognostic significance of immune scores and construct a 
      clinical nomogram to predict the survival of patients with LSCC. METHODS: The 
      clinicopathological characteristics and immune scores of 102 patients with LSCC 
      were obtained from TCGA database and a nomogram was developed. C-index and 
      calibration curves were applied to assess the performance of the model. RESULTS: 
      Patients with higher immune scores had significantly better overall survival 
      (OS). The prognostic nomogram presented a good performance in survival 
      prediction. CONCLUSIONS: High immune scores are correlated with improved OS in 
      patients with LSCC. In addition, the nomogram developed for this study may assist 
      clinicians in the prognostic evaluation of patients with LSCC.
FAU - Liao, Lianming
AU  - Liao L
AD  - Department of Laboratory Medicine, Fujian Medical University Union Hospital, 
      Fuzhou, 350001, Fujian, China.
FAU - Chen, Wei
AU  - Chen W
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, 29# 
      Xinquan Road, Fuzhou, 350001, Fujian, China.
FAU - Lai, Haichun
AU  - Lai H
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, 29# 
      Xinquan Road, Fuzhou, 350001, Fujian, China.
FAU - Yi, Xuehan
AU  - Yi X
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, 29# 
      Xinquan Road, Fuzhou, 350001, Fujian, China.
FAU - Wang, Desheng
AU  - Wang D
AUID- ORCID: 0000-0002-5844-0813
AD  - Department of Otolaryngology, Fujian Medical University Union Hospital, 29# 
      Xinquan Road, Fuzhou, 350001, Fujian, China. wangds@fjmu.edu.cn.
LA  - eng
GR  - 2019B022/Special Financial Project of Fujian Province/
GR  - 2104519#/Minimally Invasive Medical Fund of Fujian Province/
GR  - 2017-CX-23/Medical Innovation Project of Fujian Province/
PT  - Journal Article
DEP - 20200708
PL  - Germany
TA  - Eur Arch Otorhinolaryngol
JT  - European archives of oto-rhino-laryngology : official journal of the European 
      Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the 
      German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JID - 9002937
RN  - 0 (Biomarkers, Tumor)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Biomarkers, Tumor
MH  - Causality
MH  - China/epidemiology
MH  - Disease Susceptibility/*immunology
MH  - Female
MH  - Head and Neck Neoplasms/mortality/*pathology
MH  - Humans
MH  - Laryngeal Neoplasms/diagnosis/mortality/*pathology
MH  - Male
MH  - Middle Aged
MH  - Nomograms
MH  - Prognosis
MH  - Squamous Cell Carcinoma of Head and Neck/mortality/*pathology
MH  - Survival Rate
MH  - Tumor Microenvironment/immunology
OTO - NOTNLM
OT  - Immune scores
OT  - Laryngeal squamous cell cancer
OT  - Nomogram
OT  - Overall survival
OT  - Prognosis
EDAT- 2020/07/09 06:00
MHDA- 2021/02/25 06:00
CRDT- 2020/07/09 06:00
PHST- 2020/05/24 00:00 [received]
PHST- 2020/07/03 00:00 [accepted]
PHST- 2020/07/09 06:00 [pubmed]
PHST- 2021/02/25 06:00 [medline]
PHST- 2020/07/09 06:00 [entrez]
AID - 10.1007/s00405-020-06189-z [pii]
AID - 10.1007/s00405-020-06189-z [doi]
PST - ppublish
SO  - Eur Arch Otorhinolaryngol. 2021 Jan;278(1):141-148. doi: 
      10.1007/s00405-020-06189-z. Epub 2020 Jul 8.