PMID- 32652344
OWN - NLM
STAT- MEDLINE
DCOM- 20200828
LR  - 20200828
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 202
DP  - 2020 Oct 1
TI  - Complexation of Fe(III)/Catechols in atmospheric aqueous phase and the consequent 
      cytotoxicity assessment in human bronchial epithelial cells (BEAS-2B).
PG  - 110898
LID - S0147-6513(20)30737-5 [pii]
LID - 10.1016/j.ecoenv.2020.110898 [doi]
AB  - Recent research has shown that the complexation of metals-organics plays an 
      important role in atmospheric particulate matter, whose health effects should be 
      taken into account. This work investigates the interactions between catechols 
      (CAs), i.e., 4-nitrocatechol (4NC) and 4-methylcatechol (4MC), and transition 
      metals (i.e., Fe) in the aqueous phase dark reaction. The formation of Fe/CAs 
      complexes and secondary organics products are analyzed by UV-Vis spectroscopy, 
      stopped-flow spectroscopy, high-resolution mass spectrometry and Raman 
      spectroscopy, while the insoluble particulate matter formed from the CAs/Fe 
      mixtures are characterized by the FTIR, X-ray photoelectron spectroscopy (XPS) 
      and thermogravimetric-quadrupole-mass spectrometry (TG-Q-MS). On the basis of the 
      density functional theory (DFT) calculation and experimental results, the 
      possible formation pathways for the complexes of Fe(III) with 4NC (a proxy for 
      organics) are proposed. The Fe/CAs complexes and organics products perhaps have 
      significant sources of light absorption which play an important role in 
      influencing the intensity of atmospheric radiation and particulate phase 
      photochemistry. Besides, the cytotoxicity is tested as a function of 
      concentrations for CAs/Fe mixtures in BEAS-2B cells. Our results show that CAs/Fe 
      mixtures have strong association with cytotoxicity, indicating the mixtures have 
      potential influence to human health.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Zhu, Zhonghong
AU  - Zhu Z
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Zhang, Jin
AU  - Zhang J
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Lv, Guochun
AU  - Lv G
AD  - Environment Research Institute, Shandong University, Jinan, 250100, China.
FAU - George, Christian
AU  - George C
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China; University of 
      Lyon, Universite Claude Bernard Lyon 1, CNRS, IRCELYON, F-69626, Villeurbanne, 
      France; School of Environmental Science & Engineering, Shandong University, 
      Jinan, 250100, China.
FAU - Herrmann, Hartmut
AU  - Herrmann H
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China; Leibniz 
      Institute for Tropospheric Research (TROPOS), Atmospheric Chemistry Department, 
      Permoserstr. 15, D-04318, Leipzig, Germany; School of Environmental Science & 
      Engineering, Shandong University, Jinan, 250100, China.
FAU - Fu, Hongbo
AU  - Fu H
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Li, Dan
AU  - Li D
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Zhang, Liwu
AU  - Zhang L
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Sun, Xiaomin
AU  - Sun X
AD  - Environment Research Institute, Shandong University, Jinan, 250100, China.
FAU - Sun, Hao
AU  - Sun H
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Guan, Xiaohong
AU  - Guan X
AD  - School of Environmental Science & Engineering, Tongji University, Shanghai, 
      200433, China.
FAU - Li, Qing
AU  - Li Q
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Dong, Wenbo
AU  - Dong W
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Li, Xiang
AU  - Li X
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Wang, Xinke
AU  - Wang X
AD  - University of Lyon, Universite Claude Bernard Lyon 1, CNRS, IRCELYON, F-69626, 
      Villeurbanne, France.
FAU - Wang, Lin
AU  - Wang L
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Yang, Xin
AU  - Yang X
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China.
FAU - Liu, Qian
AU  - Liu Q
AD  - State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research 
      Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 
      100085, China.
FAU - Chen, Jianmin
AU  - Chen J
AD  - Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention 
      (LAP(3)), Department of Environmental Science & Engineering, Institute of 
      Atmospheric Sciences, Fudan University, Shanghai, 200438, China; Institute of 
      Eco-Chongming (IEC), 3663 N. Zhongshan Rd., Shanghai, 200062, China. Electronic 
      address: jmchen@fudan.edu.cn.
FAU - Jiang, Guibin
AU  - Jiang G
AD  - State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research 
      Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 
      100085, China.
LA  - eng
PT  - Journal Article
DEP - 20200708
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Catechols)
RN  - 0 (Ferric Compounds)
RN  - 0 (Metals)
RN  - 0 (Particulate Matter)
RN  - 059QF0KO0R (Water)
RN  - 12GLI7JGB3 (4-methylcatechol)
RN  - SW60NG75EN (4-nitrocatechol)
SB  - IM
MH  - Atmosphere/chemistry
MH  - Catechols/*chemistry/toxicity
MH  - Epithelial Cells
MH  - Ferric Compounds/*chemistry/toxicity
MH  - Humans
MH  - Mass Spectrometry
MH  - Metals
MH  - Particulate Matter
MH  - Spectrum Analysis
MH  - *Toxicity Tests
MH  - Water/chemistry
OTO - NOTNLM
OT  - 4-Methylcatechol
OT  - 4-Nitrocatechol
OT  - Aerosol
OT  - Cytotoxicity
OT  - Fe/catechols complex
OT  - Oligomer
EDAT- 2020/07/12 06:00
MHDA- 2020/08/29 06:00
CRDT- 2020/07/12 06:00
PHST- 2020/04/30 00:00 [received]
PHST- 2020/06/11 00:00 [revised]
PHST- 2020/06/12 00:00 [accepted]
PHST- 2020/07/12 06:00 [pubmed]
PHST- 2020/08/29 06:00 [medline]
PHST- 2020/07/12 06:00 [entrez]
AID - S0147-6513(20)30737-5 [pii]
AID - 10.1016/j.ecoenv.2020.110898 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2020 Oct 1;202:110898. doi: 10.1016/j.ecoenv.2020.110898. 
      Epub 2020 Jul 8.