PMID- 32652425
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20210211
LR  - 20210211
IS  - 1873-3336 (Electronic)
IS  - 0304-3894 (Linking)
VI  - 401
DP  - 2021 Jan 5
TI  - Suspect screening based on market data of polar halogenated micropollutants in 
      river water affected by wastewater.
PG  - 123377
LID - S0304-3894(20)31366-2 [pii]
LID - 10.1016/j.jhazmat.2020.123377 [doi]
AB  - Wastewater treatment plants (WWTPs) are known point sources of contaminants of 
      emerging concern (CECs) to the aquatic environment, but current knowledge is 
      mostly limited to well-known chemical structures. In this study, we sought to 
      identify unknown CECs polluting the aquatic environment through a novel suspect 
      screening approach for organohalogens, i.e. organic halogenated molecules often 
      toxic and resistant to transformation and characterised as persistent organic 
      pollutants (POPs). Surface water samples were collected with passive samplers in 
      the Fyris River catchment (Uppsala, Sweden), analysed using liquid chromatography 
      high-resolution mass spectrometry (LC-HRMS) and screened for organohalogens using 
      a suspect screening approach based on market data obtained from a regulatory 
      authority. Thirteen suspects from very different application areas were confirmed 
      or tentatively identified with high confidence, including seven previously 
      unknown structures (diflufenican, chlorzoxazone, 
      3-(3,4-dichlorophenyl)-1,1-dimethylurea, 2,4-disulfamyl-5-trifluoromethylaniline, 
      5-amino-2-chlorotoluene-4-sulfonic acid, perfluoropentane-1-sufonic acid, 
      (2-chlorophenyl)(hydroxy)methanesulfonic acid). Spatiotemporal occurrence 
      patterns were detected, which helped to understand the usage pattern of the 
      chemicals and pinpoint potential pollution sources, e.g. specific WWTPs in the 
      catchment. Several of the newly identified structures had virtually no 
      information publicly available and were detected years after their last 
      registered use, which highlights the knowledge gaps and concerns about POPs.
CI  - Copyright (c) 2020 The Authors. Published by Elsevier B.V. All rights reserved.
FAU - Menger, Frank
AU  - Menger F
AD  - Department of Aquatic Sciences and Assessment, Swedish University of Agricultural 
      Sciences (SLU), Uppsala, Sweden. Electronic address: Frank.menger@slu.se.
FAU - Ahrens, Lutz
AU  - Ahrens L
AD  - Department of Aquatic Sciences and Assessment, Swedish University of Agricultural 
      Sciences (SLU), Uppsala, Sweden.
FAU - Wiberg, Karin
AU  - Wiberg K
AD  - Department of Aquatic Sciences and Assessment, Swedish University of Agricultural 
      Sciences (SLU), Uppsala, Sweden.
FAU - Gago-Ferrero, Pablo
AU  - Gago-Ferrero P
AD  - Catalan Institute for Water Research (ICRA), Carrer Emili Grahit 101, 17003, 
      Girona, Spain; Universitat de Girona, Girona, Spain.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200704
PL  - Netherlands
TA  - J Hazard Mater
JT  - Journal of hazardous materials
JID - 9422688
SB  - IM
OTO - NOTNLM
OT  - On-site sewage treatment facilities
OT  - Organic micropollutants (OMPs)
OT  - POCIS
OT  - Source tracing
EDAT- 2020/07/12 06:00
MHDA- 2020/07/12 06:01
CRDT- 2020/07/12 06:00
PHST- 2020/02/28 00:00 [received]
PHST- 2020/06/01 00:00 [revised]
PHST- 2020/07/02 00:00 [accepted]
PHST- 2020/07/12 06:00 [pubmed]
PHST- 2020/07/12 06:01 [medline]
PHST- 2020/07/12 06:00 [entrez]
AID - S0304-3894(20)31366-2 [pii]
AID - 10.1016/j.jhazmat.2020.123377 [doi]
PST - ppublish
SO  - J Hazard Mater. 2021 Jan 5;401:123377. doi: 10.1016/j.jhazmat.2020.123377. Epub 
      2020 Jul 4.