PMID- 32653161
OWN - NLM
STAT- MEDLINE
DCOM- 20210624
LR  - 20210624
IS  - 1531-5037 (Electronic)
IS  - 0022-3468 (Linking)
VI  - 56
IP  - 4
DP  - 2021 Apr
TI  - Description of a novel chest wall anomaly: The postprematurity thoracic 
      dysplasia.
PG  - 700-705
LID - S0022-3468(20)30420-6 [pii]
LID - 10.1016/j.jpedsurg.2020.06.008 [doi]
AB  - BACKGROUND/PURPOSE: Many studies on ex-preterm babies were conducted to evaluate 
      their respiratory sequelae, but, to our knowledge, the condition described in 
      this paper was never reported before and is not included in the classifications 
      of thoracic anomalies proposed so far. METHODS: Clinical data and images of a 
      novel thoracic deformity observed in the last 10 years are shown. This anomaly is 
      characterized by an indentation of the ribs on both (less frequently one) 
      anterolateral parts of the chest wall. All our patients with this condition were 
      ex-preterm babies. We named this novel thoracic anomaly as "postprematurity 
      thoracic dysplasia" (PPTD). Possible etiopathogenetic mechanisms and treatment 
      options are discussed. RESULTS: We observed 8 patients with variable range of 
      respiratory symptoms. In 2 cases the malformation caused a severe functional 
      restriction of lung volumes and surgery was performed to improve respiratory 
      symptoms; in other cases the symptoms were mild or absent and the malformation 
      was a matter of concern only for cosmesis. CONCLUSIONS: PPTD is a novel thoracic 
      anomaly typical of ex-preterms. Clinical relevance is variable. In severe cases 
      surgery can be considered. LEVEL OF EVIDENCE: IV.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Torre, Michele
AU  - Torre M
AD  - Pediatric Thoracic and Airway Surgery Unit, IRCCS Giannina Gaslini, Via G. 
      Gaslini, 16147, Genova, Italy. Electronic address: micheletorre@gaslini.org.
FAU - Guerriero, Vittorio
AU  - Guerriero V
AD  - Pediatric Thoracic and Airway Surgery Unit, IRCCS Giannina Gaslini, Via G. 
      Gaslini, 16147, Genova, Italy.
FAU - Ramenghi, Luca
AU  - Ramenghi L
AD  - Neonatal Pathology Unit, IRCCS Giannina Gaslini, Via G. Gaslini, 16147, Genova, 
      Italy.
FAU - Rizzo, Francesca
AU  - Rizzo F
AD  - Radiology Department, IRCCS Giannina Gaslini, Via G. Gaslini, 16147, Genova, 
      Italy.
FAU - Gallizia, Annalisa
AU  - Gallizia A
AD  - Pediatric Pneumology Unit, IRCCS Giannina Gaslini, Via G. Gaslini, 16147, Genova, 
      Italy.
FAU - Sacco, Oliviero
AU  - Sacco O
AD  - Pediatric Pneumology Unit, IRCCS Giannina Gaslini, Via G. Gaslini, 16147, Genova, 
      Italy.
LA  - eng
PT  - Journal Article
DEP - 20200613
PL  - United States
TA  - J Pediatr Surg
JT  - Journal of pediatric surgery
JID - 0052631
SB  - IM
MH  - Humans
MH  - Infant, Newborn
MH  - Lung Volume Measurements
MH  - Ribs
MH  - *Thoracic Wall
OTO - NOTNLM
OT  - Chest wall anomaly
OT  - Classification of thoracic deformities
OT  - Prematurity
OT  - Rib
OT  - Thoracic malformation
OT  - Thoracoplasty
EDAT- 2020/07/13 06:00
MHDA- 2021/06/25 06:00
CRDT- 2020/07/13 06:00
PHST- 2020/04/24 00:00 [received]
PHST- 2020/05/18 00:00 [revised]
PHST- 2020/06/05 00:00 [accepted]
PHST- 2020/07/13 06:00 [pubmed]
PHST- 2021/06/25 06:00 [medline]
PHST- 2020/07/13 06:00 [entrez]
AID - S0022-3468(20)30420-6 [pii]
AID - 10.1016/j.jpedsurg.2020.06.008 [doi]
PST - ppublish
SO  - J Pediatr Surg. 2021 Apr;56(4):700-705. doi: 10.1016/j.jpedsurg.2020.06.008. Epub 
      2020 Jun 13.