PMID- 32660147
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2304-8158 (Print)
IS  - 2304-8158 (Electronic)
IS  - 2304-8158 (Linking)
VI  - 9
IP  - 7
DP  - 2020 Jul 9
TI  - Multifamily Determination of Phytohormones and Acidic Herbicides in Fruits and 
      Vegetables by Liquid Chromatography-Tandem Mass Spectrometry under Accredited 
      Conditions.
LID - 10.3390/foods9070906 [doi]
LID - 906
AB  - A 7-min multifamily residue method for the simultaneous quantification and 
      confirmation of 8 phytohormones and 27 acidic herbicides in fruit and vegetables 
      using ultra high-performance liquid chromatography (UHPLC) coupled to tandem mass 
      spectrometry (MS/MS) was developed, validated according to SANTE 12682/2019, and 
      accredited according to UNE-EN-ISO/IEC 17025:2017. Due to the special 
      characteristics of these kinds of compounds, a previous step of alkaline 
      hydrolysis was carried out for breaking conjugates that were potentially formed 
      due to the interactions of the analytes with other components present in the 
      matrix. Sample treatment was based on QuEChERS extraction and optimum detection 
      conditions were individually optimized for each analyte. Cucumber (for high water 
      content commodities) and orange (for high acid and high water content samples) 
      were selected as representative matrices. Matrix-matched calibration was used, 
      and all the validation criteria established in the SANTE guidelines were 
      satisfied. Uncertainty estimation for each target compound was included in the 
      validation process. The proposed method was applied to the analysis of more than 
      450 samples of cucumber, orange, tomato, watermelon, and zucchini during one 
      year. Several compounds, such as 2,4-dichlorophenoxyacetic acid (2,4-D), 
      4-(3-indolyl)butyric acid (IBA), dichlorprop (2,4-DP), 2-methyl-4-chlorophenoxy 
      acetic acid (MCPA), and triclopyr were found, but always at concentrations lower 
      than the maximum residue level (MRL) regulated by the EU.
FAU - Grande Martinez, Angel
AU  - Grande Martinez A
AD  - Department of Chemistry and Physics (Analytical Chemistry Area), Agrifood Campus 
      of International Excellence ceiA3, University of Almeria, E-04120 Almeria, Spain.
AD  - Bio-Clinical Analytical Laboratory (LAB), PITA (Almeria Science and Technology 
      Park, Albert Einstein 7, E-04131 Almeria, Spain.
FAU - Arrebola Liebanas, Francisco Javier
AU  - Arrebola Liebanas FJ
AD  - Department of Chemistry and Physics (Analytical Chemistry Area), Agrifood Campus 
      of International Excellence ceiA3, University of Almeria, E-04120 Almeria, Spain.
FAU - Santiago Valverde, Rosario
AU  - Santiago Valverde R
AD  - Bio-Clinical Analytical Laboratory (LAB), PITA (Almeria Science and Technology 
      Park, Albert Einstein 7, E-04131 Almeria, Spain.
FAU - Hernandez Torres, Maria Elena
AU  - Hernandez Torres ME
AD  - Bio-Clinical Analytical Laboratory (LAB), PITA (Almeria Science and Technology 
      Park, Albert Einstein 7, E-04131 Almeria, Spain.
FAU - Ramirez Casinello, Juan
AU  - Ramirez Casinello J
AD  - Bio-Clinical Analytical Laboratory (LAB), PITA (Almeria Science and Technology 
      Park, Albert Einstein 7, E-04131 Almeria, Spain.
FAU - Garrido Frenich, Antonia
AU  - Garrido Frenich A
AUID- ORCID: 0000-0002-7904-7842
AD  - Department of Chemistry and Physics (Analytical Chemistry Area), Agrifood Campus 
      of International Excellence ceiA3, University of Almeria, E-04120 Almeria, Spain.
LA  - eng
PT  - Journal Article
DEP - 20200709
PL  - Switzerland
TA  - Foods
JT  - Foods (Basel, Switzerland)
JID - 101670569
PMC - PMC7404484
OTO - NOTNLM
OT  - UHPLC-MS/MS
OT  - acidic herbicides
OT  - fruits and vegetables
OT  - multifamily method
OT  - phytohormones
COIS- The authors declare no conflict of interest.
EDAT- 2020/07/15 06:00
MHDA- 2020/07/15 06:01
PMCR- 2020/07/09
CRDT- 2020/07/15 06:00
PHST- 2020/05/15 00:00 [received]
PHST- 2020/07/05 00:00 [revised]
PHST- 2020/07/06 00:00 [accepted]
PHST- 2020/07/15 06:00 [entrez]
PHST- 2020/07/15 06:00 [pubmed]
PHST- 2020/07/15 06:01 [medline]
PHST- 2020/07/09 00:00 [pmc-release]
AID - foods9070906 [pii]
AID - foods-09-00906 [pii]
AID - 10.3390/foods9070906 [doi]
PST - epublish
SO  - Foods. 2020 Jul 9;9(7):906. doi: 10.3390/foods9070906.