PMID- 32664014 OWN - NLM STAT- MEDLINE DCOM- 20210215 LR - 20210215 IS - 1573-2517 (Electronic) IS - 0165-0327 (Linking) VI - 274 DP - 2020 Sep 1 TI - Prevalence of depressive symptoms in patients with Heart Failure in China: a meta-analysis of comparative studies and epidemiological surveys. PG - 774-783 LID - S0165-0327(20)30664-9 [pii] LID - 10.1016/j.jad.2020.05.099 [doi] AB - BACKGROUND: Although depressive symptoms is a frequent psychiatric comorbidity in people with Heart Failure (HF) in China, its prevalence was not estimated. This is a meta-analysis of studies examining depressive symptoms in HF patients in China. METHODS: The following databases including PubMed, the Cochrace Library, Embase, China National Knowledge Infrastructure (CNKI), WanFang and VIP were independently and systematically searched from inception until March 31, 2019. Statistical analyses were performed using the Stata 13.0 software. The pooled prevalence of depressive symptoms was performed using a random-effects model. In addition, subgroup analysis was conducted based on the New York Heart Association (NYHA) functional class, the assessment tools of depression and gender. RESULTS: Altogether 53 studies (10649 participants) met the inclusion criteria for the analysis. The point prevalence of depressive symptoms in HF was 43%. In subgroup analyses, the prevalence of depressive symptoms was higher in females than in males (46% vs 34%, respectively), and the prevalence of depressive symptoms positively correlated with New York Heart Association functional classes (II 28%, III 46%, IV 52%) . Rates of depression were highest when measured using BDI scale (62%), and lowest when measured using the CES-D (31%). CONCLUSIONS: This meta-analysis confirmed that the prevalence of depressive symptoms was common in HF patients in China and it is related to the severity of heart failure, gender and the diversity of assessment tools. Appropriate strategies for prevention and treatment of depressive symptoms in this population need greater attention. CI - Copyright (c) 2020 Elsevier B.V. All rights reserved. FAU - Lin, Xiao-Xiao AU - Lin XX AD - Department of cardiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine. FAU - Gao, Bei-Bei AU - Gao BB AD - Department of cardiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine. FAU - Huang, Jin-Yu AU - Huang JY AD - Department of cardiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine. Electronic address: hjyuo@163.com. LA - eng PT - Journal Article PT - Meta-Analysis PT - Research Support, Non-U.S. Gov't DEP - 20200531 PL - Netherlands TA - J Affect Disord JT - Journal of affective disorders JID - 7906073 SB - IM MH - China/epidemiology MH - *Depression/epidemiology MH - Female MH - *Heart Failure/epidemiology MH - Humans MH - Male MH - Prevalence MH - Surveys and Questionnaires OTO - NOTNLM OT - China OT - Depressive symptoms OT - Heart failure OT - Meta-analysis OT - prevalence COIS- Declaration of Competing Interest The authors declare that they have no conflict of interest related to this work. EDAT- 2020/07/16 06:00 MHDA- 2021/02/16 06:00 CRDT- 2020/07/16 06:00 PHST- 2020/02/25 00:00 [received] PHST- 2020/04/05 00:00 [revised] PHST- 2020/05/15 00:00 [accepted] PHST- 2020/07/16 06:00 [entrez] PHST- 2020/07/16 06:00 [pubmed] PHST- 2021/02/16 06:00 [medline] AID - S0165-0327(20)30664-9 [pii] AID - 10.1016/j.jad.2020.05.099 [doi] PST - ppublish SO - J Affect Disord. 2020 Sep 1;274:774-783. doi: 10.1016/j.jad.2020.05.099. Epub 2020 May 31.