PMID- 3266940
OWN - NLM
STAT- MEDLINE
DCOM- 19890727
LR  - 20061115
IS  - 0181-5512 (Print)
IS  - 0181-5512 (Linking)
VI  - 11
IP  - 11
DP  - 1988
TI  - [Epidemiology of Bietti's keratopathy. Study of risk factors in Central Africa 
      (Chad)].
PG  - 733-40
AB  - Climatic Droplet keratopathy (synonyms: spheroidal degeneration, Bietti's 
      keratopathy) is a corneal degeneration characterized by an opacification at the 
      level of the Bowman's membrane in the area of the palpebral fissure. It is 
      particularly common in areas of bright sunlight and in Labrador; ultraviolet 
      light thus being thought at its genesis. Two objectives were included in this 
      study: studying the Climatic Droplet Keratopathy (CDK) prevalence by looking for 
      the influence of the climatic factor; looking for possible association with three 
      other degenerative ocular diseases: cataract, open-angle, glaucoma and 
      exfoliation syndrome. A random cluster sampling survey was carried out in 
      different climatic areas in Chad (N = 3,241 people). The resulting analysis 
      showed a significant relation between the CDK prevalence and the kind of climate: 
      the more the climate is dry; the more the higher the frequency: subdesert area = 
      1.57%, Sahelian area = 0.73%, tropical area = 0.18% (p less than 0.0001, rate 
      standardized to age). The CDK occurs earlier in the subdesert area (mean age = 
      60.0) than in the Sahelian one (mean age = 66.7) (p less than 0.05). The CDK only 
      exists among people age 40 or older, and is more frequent among males than 
      females (p less than 0.005). The cataract is more frequent among individuals 
      having a CDK than among those without it: relative risk = 4.3 (C.I.: 2.3-7.9 p 
      less than 0.00001) (Mantel-Haenszel's method with adjustment to climate, age and 
      sex). As for open-angle glaucoma, it is more frequent among individuals suffering 
      from CDK: relative risk = 4.2 (p = 0.05). Finally, we noticed that the 
      exfoliation syndrome was 5 times more frequent among chadians suffering from a 
      CDK (p less than 0.02).(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Resnikoff, S
AU  - Resnikoff S
LA  - fre
PT  - English Abstract
PT  - Journal Article
TT  - Epidemiologie de la keratopathie de Bietti. Etude des facteurs de risque en 
      Afrique centrale (Tchad).
PL  - France
TA  - J Fr Ophtalmol
JT  - Journal francais d'ophtalmologie
JID - 7804128
SB  - IM
MH  - Adult
MH  - Africa, Central
MH  - Aged
MH  - Cataract/complications
MH  - Chad
MH  - Corneal Dystrophies, Hereditary/complications/*epidemiology
MH  - Desert Climate
MH  - Female
MH  - Glaucoma/complications
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Risk Factors
MH  - Time Factors
EDAT- 1988/01/01 00:00
MHDA- 1988/01/01 00:01
CRDT- 1988/01/01 00:00
PHST- 1988/01/01 00:00 [pubmed]
PHST- 1988/01/01 00:01 [medline]
PHST- 1988/01/01 00:00 [entrez]
PST - ppublish
SO  - J Fr Ophtalmol. 1988;11(11):733-40.