PMID- 32682310
OWN - NLM
STAT- MEDLINE
DCOM- 20210709
LR  - 20210709
IS  - 1878-0334 (Electronic)
IS  - 1871-4021 (Linking)
VI  - 14
IP  - 5
DP  - 2020 Sep-Oct
TI  - Prevalence of Metabolic Syndrome by different definitions, and its association 
      with type 2 diabetes, pre-diabetes, and cardiovascular disease risk in Brazil.
PG  - 1217-1224
LID - S1871-4021(20)30161-2 [pii]
LID - 10.1016/j.dsx.2020.05.043 [doi]
AB  - BACKGROUND AND AIMS: Metabolic Syndrome (MS) is increasing in developing 
      countries. Different definitions of MS lead to discrepancies in prevalence 
      estimates and applicability. We assessed the prevalence of MS as defined by the 
      International Diabetes Federation (IDF), modified National Cholesterol Education 
      Program Adult Treatment Plan III (Modified NCEP) and Joint Interim Statement 
      (JIS); compared the diagnostic performance and association of these definitions 
      of MS with pre-diabetes, type 2 diabetes mellitus (T2DM) and cardiovascular 
      disease (CVD) risk. METHODS: A total of 714 randomly selected subjects from 
      Northeastern Brazil were investigated in a cross-sectional study. 
      Sociodemographic, anthropometric, and clinical data were recorded. Diagnostic 
      test performance measures assessed the ability of the different MS definitions to 
      identify those with pre-diabetes, T2DM and increased CVD risk. RESULTS: The 
      adjusted prevalence of MS was 36.1% applying the JIS criteria, 35.1% the IDF and 
      29.5% Modified NCEP. Women were more affected by MS according to all definitions. 
      MS was significantly associated with pre-diabetes, T2DM and CVD risk following 
      the three definitions. However, the JIS and IDF definitions showed higher 
      sensitivity than the Modified NCEP to identify pre-diabetes, T2DM and CVD risk. 
      The odds ratios for those conditions were not significantly different when 
      comparing the definitions. CONCLUSIONS: MS is highly prevalent in Brazil, 
      particularly among those with pre-diabetes, T2DM, and high CVD risk. The IDF and 
      JIS criteria may be better suited in the Brazilian population to identify 
      pre-diabetes, T2DM and CVD risk. This may also signify the importance of the 
      assessment of MS in clinical practice.
CI  - Copyright (c) 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.
FAU - do Vale Moreira, Nayla Cristina
AU  - do Vale Moreira NC
AD  - Institute of Health and Society, Department of Community Medicine and Global 
      Health, University of Oslo (UiO), Oslo, Norway; Faculty of Medicine, Federal 
      University of Ceara (FAMED-UFC), Fortaleza, Ceara, Brazil. Electronic address: 
      naylacristinam@yahoo.com.br.
FAU - Hussain, Akhtar
AU  - Hussain A
AD  - Faculty of Medicine, Federal University of Ceara (FAMED-UFC), Fortaleza, Ceara, 
      Brazil; Centre for Global Health Research, Diabetic Association of Bangladesh, 
      Dhaka, Bangladesh; Faculty of Health Sciences, Nord University, Bodo, Norway.
FAU - Bhowmik, Bishwajit
AU  - Bhowmik B
AD  - Institute of Health and Society, Department of Community Medicine and Global 
      Health, University of Oslo (UiO), Oslo, Norway; Centre for Global Health 
      Research, Diabetic Association of Bangladesh, Dhaka, Bangladesh.
FAU - Mdala, Ibrahimu
AU  - Mdala I
AD  - Institute of Health and Society, Department of General Practice, University of 
      Oslo (UiO), Oslo, Norway.
FAU - Siddiquee, Tasnima
AU  - Siddiquee T
AD  - Centre for Global Health Research, Diabetic Association of Bangladesh, Dhaka, 
      Bangladesh.
FAU - Fernandes, Virginia Oliveira
AU  - Fernandes VO
AD  - Faculty of Medicine, Federal University of Ceara (FAMED-UFC), Fortaleza, Ceara, 
      Brazil.
FAU - Montenegro Junior, Renan Magalhaes
AU  - Montenegro Junior RM
AD  - Faculty of Medicine, Federal University of Ceara (FAMED-UFC), Fortaleza, Ceara, 
      Brazil.
FAU - Meyer, Haakon E
AU  - Meyer HE
AD  - Institute of Health and Society, Department of Community Medicine and Global 
      Health, University of Oslo (UiO), Oslo, Norway.
LA  - eng
PT  - Journal Article
DEP - 20200712
PL  - Netherlands
TA  - Diabetes Metab Syndr
JT  - Diabetes & metabolic syndrome
JID - 101462250
SB  - IM
MH  - Adult
MH  - Brazil/epidemiology
MH  - Cardiovascular Diseases/*epidemiology
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*physiopathology
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Metabolic Syndrome/*physiopathology
MH  - Middle Aged
MH  - Prediabetic State/*physiopathology
MH  - Prevalence
MH  - Prognosis
MH  - Risk Factors
MH  - Young Adult
OTO - NOTNLM
OT  - Brazil
OT  - Cardiovascular disease risk
OT  - Metabolic syndrome
OT  - Pre-diabetes
OT  - Type 2 diabetes mellitus
COIS- Declaration of competing interest The authors declare that they have no competing 
      interests. This study received financial sponsorship from the University of Oslo 
      and Ivar Helles Foundation. Nevertheless, the funders had no role in the study 
      design; in the collection, analyses, or interpretation of data; in writing the 
      report, or in the decision to publish the results.
EDAT- 2020/07/19 06:00
MHDA- 2021/07/10 06:00
CRDT- 2020/07/19 06:00
PHST- 2020/01/05 00:00 [received]
PHST- 2020/05/26 00:00 [revised]
PHST- 2020/05/28 00:00 [accepted]
PHST- 2020/07/19 06:00 [pubmed]
PHST- 2021/07/10 06:00 [medline]
PHST- 2020/07/19 06:00 [entrez]
AID - S1871-4021(20)30161-2 [pii]
AID - 10.1016/j.dsx.2020.05.043 [doi]
PST - ppublish
SO  - Diabetes Metab Syndr. 2020 Sep-Oct;14(5):1217-1224. doi: 
      10.1016/j.dsx.2020.05.043. Epub 2020 Jul 12.