PMID- 32684609 OWN - NLM STAT- MEDLINE DCOM- 20210629 LR - 20210629 IS - 1347-7439 (Electronic) IS - 0916-7250 (Print) IS - 0916-7250 (Linking) VI - 82 IP - 9 DP - 2020 Oct 7 TI - Inclusion body hepatitis caused by Aviadenovirus in a tropical screech owl (Megascops choliba). PG - 1341-1345 LID - 10.1292/jvms.20-0316 [doi] AB - In 2016, tropical screech owl (Megascops choliba) (Tso) chicks were suddenly found dead in a Japanese breeding facility. We autopsied a 9-day-old Tso and discovered white spots scattered on the liver surface. Multifocal necrosis was diffused, and macrophages had infiltrated the necrotic hepatic lesions. Hepatocytes contained numerous intranuclear inclusion bodies. Immunohistochemical staining detected Adenovirus antigen only in the liver. Next, PCR and sequencing (LC536616) identified Tso Adenovirus (TsoAd). Basic Local Alignment Search Tool (BLAST) and phylogenic analyzes suggested TsoAd is an owl Aviadenovirus. Our study contributes to an improved understanding of infectious disease among captive raptors. FAU - Komatsu, Tetsuya AU - Komatsu T AD - Aichi Prefectural Chuo Livestock Hygiene Service Center, 1-306 Jizono, Miaicho, Okazaki, Aichi 444-0805, Japan. FAU - Kubo, Takashi AU - Kubo T AD - Aichi Prefectural Chuo Livestock Hygiene Service Center, 1-306 Jizono, Miaicho, Okazaki, Aichi 444-0805, Japan. FAU - Kitou, Rena AU - Kitou R AD - Aichi Prefectural Chuo Livestock Hygiene Service Center, 1-306 Jizono, Miaicho, Okazaki, Aichi 444-0805, Japan. FAU - Kawamoto, Naomi AU - Kawamoto N AD - Aichi Prefectural Chuo Livestock Hygiene Service Center, 1-306 Jizono, Miaicho, Okazaki, Aichi 444-0805, Japan. FAU - Mase, Masaji AU - Mase M AD - Division of Viral Disease and Epidemiology Research, National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan. FAU - Yamamoto, Yu AU - Yamamoto Y AD - Division of Pathology and Pathophysiology, National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan. FAU - Shibahara, Tomoyuki AU - Shibahara T AD - Division of Pathology and Pathophysiology, National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), 3-1-5 Kannondai, Tsukuba, Ibaraki 305-0856, Japan. AD - Department of Veterinary Science, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku-oraikita, Izumisano, Osaka 598-8531, Japan. LA - eng PT - Journal Article DEP - 20200717 PL - Japan TA - J Vet Med Sci JT - The Journal of veterinary medical science JID - 9105360 SB - IM MH - *Adenoviridae Infections/veterinary MH - Animals MH - *Aviadenovirus/genetics MH - Chickens MH - *Hepatitis MH - Inclusion Bodies MH - *Poultry Diseases MH - *Strigiformes/virology PMC - PMC7538312 OTO - NOTNLM OT - Aviadenovirus OT - Japan OT - inclusion body hepatitis OT - tropical screech owl EDAT- 2020/07/21 06:00 MHDA- 2021/06/30 06:00 PMCR- 2020/09/01 CRDT- 2020/07/21 06:00 PHST- 2020/07/21 06:00 [pubmed] PHST- 2021/06/30 06:00 [medline] PHST- 2020/07/21 06:00 [entrez] PHST- 2020/09/01 00:00 [pmc-release] AID - 20-0316 [pii] AID - 10.1292/jvms.20-0316 [doi] PST - ppublish SO - J Vet Med Sci. 2020 Oct 7;82(9):1341-1345. doi: 10.1292/jvms.20-0316. Epub 2020 Jul 17.