PMID- 32685788 OWN - NLM STAT- MEDLINE DCOM- 20210608 LR - 20210608 IS - 2501-2533 (Electronic) IS - 2457-4325 (Print) IS - 2457-4325 (Linking) VI - 64 IP - 2 DP - 2020 Apr-Jun TI - The role of Visual Evoked Potential (VEP) in monitoring the progression and in guiding the treatment of glaucoma patients with poor compliance. PG - 205-212 AB - Objectives: The objectives of the present study were to analyze the possibility of using pattern VEPs (VEP of pattern type) in glaucoma patients and their role in the follow-up and coordination/ management of anti-glaucoma treatment. Patients and Methods: This is a prospective study on 54 eyes of 30 consecutive glaucoma patients, whose compliance capacity did not allow automatic perimetry and OCT scan to be carried out. The patients were divided into two groups: group A - the study group and group B - the control group. All patients underwent FO exam and pachymetry, plus VEP exam for group A patients. Patients were analyzed at the initial visit and at 1 month, 3, 6, 12 months. Statistical analysis was made using t-test, ANOVA, Fisher test and Pearson correlation coefficient. Results: These participants presented a positive correlation between C/ D ratio and the latency of the P100 wave at 1 degree and a negative correlation between C/ D ratio and the amplitude of the P100 wave both at 1 degree (60 arc minutes) and at 0.25 degrees (15 arc minutes). During the study, the values of the latent P100 changed statistically at 6 months and at 1 year. Using all the data, the authors of the study considered it necessary to modify the treatment for 2 patients out of 13 in group B and for 9 patients out of 16 in group A (p = 0,02892). Conclusions: VEP supplies additional/ further data that significantly help guiding the treatment and monitoring the progression, therefore, it should be part of the routine examination for these patients. Further studies are necessary to deepen our understanding of the visual evoked potentials utility. CI - (c)Romanian Society of Ophthalmology. FAU - Firan, Anne Marie AU - Firan AM AD - Barnsley District Hospital, NHS trust, England. FAU - Iancu, Raluca Claudia AU - Iancu RC AD - Department of Ophthalmology, University Emergency Hospital, Bucharest, Romania. FAU - Bujor, Inna Adriana AU - Bujor IA AD - Department of Ophthalmology, University Emergency Hospital, Bucharest, Romania. FAU - Ciuluvica, Radu Constantin AU - Ciuluvica RC AD - "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. FAU - Tudosescu, Ruxandra AU - Tudosescu R AD - Department of Ophthalmology, "Regina Maria" Private Health Care, Bucharest, Romania. FAU - Ungureanu, Emil AU - Ungureanu E AD - Department of Ophthalmology, University Emergency Hospital, Bucharest, Romania. FAU - Pasca, Irena Gabriela AU - Pasca IG AD - Department of Ophthalmology, University Emergency Hospital, Bucharest, Romania. FAU - Voinea, Liliana AU - Voinea L AD - Department of Ophthalmology, University Emergency Hospital, Bucharest, Romania. FAU - Istrate, Sinziana AU - Istrate S AD - Department of Ophthalmology, "Regina Maria" Private Health Care, Bucharest, Romania. LA - eng PT - Journal Article PL - Romania TA - Rom J Ophthalmol JT - Romanian journal of ophthalmology JID - 101677459 RN - 0 (Antihypertensive Agents) SB - IM MH - Aged MH - Aged, 80 and over MH - Antihypertensive Agents/*therapeutic use MH - Disease Progression MH - Evoked Potentials, Visual/*physiology MH - Female MH - Follow-Up Studies MH - Glaucoma/drug therapy/*physiopathology MH - *Guideline Adherence MH - Humans MH - Intraocular Pressure/*physiology MH - Male MH - Middle Aged MH - Monitoring, Physiologic/*methods MH - *Patient Compliance MH - Prospective Studies PMC - PMC7339685 OTO - NOTNLM OT - amplitude OT - glaucoma OT - latency OT - visual evoked potential EDAT- 2020/07/21 06:00 MHDA- 2021/06/09 06:00 PMCR- 2020/05/01 CRDT- 2020/07/21 06:00 PHST- 2020/07/21 06:00 [entrez] PHST- 2020/07/21 06:00 [pubmed] PHST- 2021/06/09 06:00 [medline] PHST- 2020/05/01 00:00 [pmc-release] AID - RomJOphthalmol-64-205 [pii] PST - ppublish SO - Rom J Ophthalmol. 2020 Apr-Jun;64(2):205-212.