PMID- 32693644
OWN - NLM
STAT- MEDLINE
DCOM- 20210811
LR  - 20210811
IS  - 1502-7708 (Electronic)
IS  - 0036-5521 (Linking)
VI  - 55
IP  - 8
DP  - 2020 Aug
TI  - Colonoscopy adverse events: are we getting the full picture?
PG  - 979-987
LID - 10.1080/00365521.2020.1792541 [doi]
AB  - INTRODUCTION: Colonoscopy adverse events (AEs) are commonly underreported and 
      standardised reporting is rarely used. We aimed to investigate AEs associated 
      with colonoscopy in a real world setting, using the American Society of 
      Gastrointestinal Endoscopy (ASGE) lexicon. METHODS: This retrospective cohort 
      study of AEs related to outpatient colonoscopies performed in the North Denmark 
      Region from 2015 to 2018 identified AEs from readmission within eight days or 
      death within 30 days of colonoscopy. AEs were investigated in electronic health 
      records and categorised, attributed and graded according to the ASGE lexicon. 
      RESULTS: Of 49,445 colonoscopies performed, 1141 were potentially associated with 
      AEs (23.07 per thousand). Electronic health record review left 489 AEs attributed to 
      colonoscopy (9.9 per thousand); categorised as cardiovascular (0.65 per thousand), pulmonary (0.36 per thousand), 
      thromboembolic (0.10 per thousand), instrumental incl. perforations (0.99 per thousand), bleeding 
      (3.07 per thousand), infection (0.87 per thousand), drug reactions (0.04 per thousand), pain (2.00 per thousand), integument 
      (damage to skin/bones) (0.34 per thousand) and other (1.62 per thousand) AEs. Ten (0.20 per thousand) AEs were fatal, 
      but only one was procedure related (perforation). All shearing force perforations 
      occurred in the sigmoid colon. Most polypectomy perforations occurred in the 
      caecum (60%). CONCLUSIONS: Colonoscopy carries important procedure and 
      non-procedure related risks. Non-procedure related AEs are likely underreported. 
      Better attention to patients with pre-existing diseases and further colonoscopist 
      training may lower AE rates. A standardised colonoscopy AE reporting system is 
      warranted.
FAU - Pedersen, Lasse
AU  - Pedersen L
AD  - Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, 
      Denmark.
FAU - Sorensen, Nina
AU  - Sorensen N
AD  - Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, 
      Denmark.
FAU - Lindorff-Larsen, Karen
AU  - Lindorff-Larsen K
AD  - Nordsim: Center for Skills Training and Simulation, Aalborg University Hospital, 
      Aalborg, Denmark.
FAU - Carlsen, Charlotte Green
AU  - Carlsen CG
AD  - Emergency Department, Aarhus University Hospital, Aarhus, Denmark.
FAU - Wensel, Nina
AU  - Wensel N
AD  - Department of Surgical Gastroenterology, North Denmark Regional Hospital, 
      Hjorring, Denmark.
FAU - Torp-Pedersen, Christian
AU  - Torp-Pedersen C
AD  - Department of Cardiology and Clinical Investigation, Hillerod and Department of 
      Cardiology, Nordsjaellands Hospital, Aalborg University Hospital, Aalborg, 
      Denmark.
FAU - Bernstein, Inge
AU  - Bernstein I
AD  - Department of Surgical Gastroenterology, Aalborg University Hospital, Aalborg, 
      Denmark.
LA  - eng
PT  - Journal Article
DEP - 20200721
PL  - England
TA  - Scand J Gastroenterol
JT  - Scandinavian journal of gastroenterology
JID - 0060105
SB  - IM
MH  - *Colonoscopy/adverse effects
MH  - Endoscopy, Gastrointestinal
MH  - Hemorrhage
MH  - Humans
MH  - *Intestinal Perforation
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Endoscopy-general
OT  - GI-bleeding
OT  - endoscopy-interventional
EDAT- 2020/07/23 06:00
MHDA- 2021/08/12 06:00
CRDT- 2020/07/23 06:00
PHST- 2020/07/23 06:00 [pubmed]
PHST- 2021/08/12 06:00 [medline]
PHST- 2020/07/23 06:00 [entrez]
AID - 10.1080/00365521.2020.1792541 [doi]
PST - ppublish
SO  - Scand J Gastroenterol. 2020 Aug;55(8):979-987. doi: 
      10.1080/00365521.2020.1792541. Epub 2020 Jul 21.