PMID- 32698325
OWN - NLM
STAT- MEDLINE
DCOM- 20210315
LR  - 20210315
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 12
IP  - 7
DP  - 2020 Jul 20
TI  - Low-Glycemic-Index/Load Desserts Decrease Glycemic and Insulinemic Response in 
      Patients with Type 2 Diabetes Mellitus.
LID - 10.3390/nu12072153 [doi]
LID - 2153
AB  - Diabetes mellitus is a chronic disease whose prevalence is growing worldwide. 
      Consumption of desserts with low glycemic index (GI) and low glycemic load (GL) 
      in a balanced hypocaloric diet has a positive impact on anthropometric and 
      metabolic parameters in patients with type 2 diabetes mellitus (T2DM). The aim of 
      the present study was to evaluate the glycemic and insulinemic response after 
      consumption of desserts with low GI/GL in patients with T2DM. Fifty-one patients 
      consumed either 83 g of the conventional dessert or 150 g of the low GI/GL 
      dessert in random order after an overnight fast. Serum glucose, triglycerides, 
      and insulin were measured at baseline (immediately before ingestion) and at 30, 
      60, 90, and 120 min postprandially. Subjective appetite measurements were 
      performed using visual analog scales (VASs). There were significant differences 
      at 30 (p = 0.014), 60 (p < 0.001), and 90 min (p < 0.001) postprandially between 
      the two desserts for glucose and at 30 (p = 0.014) and 60 min (p = 0.033) 
      postprandially for insulin. Glucose iAUC was significantly lower in low-GI/GL 
      dessert compared to control (p < 0.001). Serum triglycerides and insulin iAUC did 
      not differ between the two trials. Fullness VAS ratings were significantly higher 
      after consumption of the low-GI/GL dessert compared to conventional dessert. 
      Likewise, hunger, additional food, and additional food quantity VAS ratings were 
      significantly lower after the consumption of the low-GI/GL dessert compared to 
      control. Consumption of low-GI/GL dessert indicates a positive impact on 
      metabolic parameters in T2DM patients.
FAU - Argiana, Vasiliki
AU  - Argiana V
AD  - Diabetes Center, First Department of Propaedeutic Internal Medicine, Medical 
      School, National and Kapodistrian University of Athens, Laiko General Hospital, 
      15772 Athens, Greece.
FAU - Kanellos, Panagiotis Tau
AU  - Kanellos PTau
AD  - Diabetes Center, First Department of Propaedeutic Internal Medicine, Medical 
      School, National and Kapodistrian University of Athens, Laiko General Hospital, 
      15772 Athens, Greece.
FAU - Eleftheriadou, Ioanna
AU  - Eleftheriadou I
AD  - Diabetes Center, First Department of Propaedeutic Internal Medicine, Medical 
      School, National and Kapodistrian University of Athens, Laiko General Hospital, 
      15772 Athens, Greece.
FAU - Tsitsinakis, Georgios
AU  - Tsitsinakis G
AD  - Diabetes Center, First Department of Propaedeutic Internal Medicine, Medical 
      School, National and Kapodistrian University of Athens, Laiko General Hospital, 
      15772 Athens, Greece.
FAU - Perrea, Despoina
AU  - Perrea D
AD  - Laboratory of Experimental Surgery and Surgical Research N.S. Christeas, National 
      and Kapodistrian University of Athens, 15772 Athens, Greece.
FAU - Tentolouris, Nikolaos K
AU  - Tentolouris NK
AD  - Diabetes Center, First Department of Propaedeutic Internal Medicine, Medical 
      School, National and Kapodistrian University of Athens, Laiko General Hospital, 
      15772 Athens, Greece.
LA  - eng
PT  - Journal Article
DEP - 20200720
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
RN  - 0 (Blood Glucose)
RN  - 0 (Insulin)
RN  - 0 (Triglycerides)
RN  - VCQ006KQ1E (Xylitol)
SB  - IM
MH  - Blood Glucose/metabolism
MH  - *Caloric Restriction
MH  - Diabetes Mellitus, Type 2/*diet therapy/*metabolism
MH  - *Diet, Carbohydrate-Restricted
MH  - *Diet, Reducing
MH  - Female
MH  - *Glycemic Index
MH  - *Glycemic Load
MH  - Humans
MH  - Insulin/blood/*metabolism
MH  - Male
MH  - Middle Aged
MH  - Nutritional Physiological Phenomena/*physiology
MH  - Postprandial Period
MH  - Triglycerides/blood
MH  - Xylitol/administration & dosage
PMC - PMC7400801
OTO - NOTNLM
OT  - diabetes
OT  - glucose
OT  - glycemic index
OT  - glycemic load
OT  - insulin
OT  - xylitol
COIS- The authors declare they have no conflict of interest.
EDAT- 2020/07/24 06:00
MHDA- 2021/03/16 06:00
PMCR- 2020/07/01
CRDT- 2020/07/24 06:00
PHST- 2020/06/26 00:00 [received]
PHST- 2020/07/10 00:00 [revised]
PHST- 2020/07/16 00:00 [accepted]
PHST- 2020/07/24 06:00 [entrez]
PHST- 2020/07/24 06:00 [pubmed]
PHST- 2021/03/16 06:00 [medline]
PHST- 2020/07/01 00:00 [pmc-release]
AID - nu12072153 [pii]
AID - nutrients-12-02153 [pii]
AID - 10.3390/nu12072153 [doi]
PST - epublish
SO  - Nutrients. 2020 Jul 20;12(7):2153. doi: 10.3390/nu12072153.