PMID- 32699183
OWN - NLM
STAT- MEDLINE
DCOM- 20210324
LR  - 20221207
IS  - 1945-4589 (Electronic)
IS  - 1945-4589 (Linking)
VI  - 12
IP  - 14
DP  - 2020 Jul 22
TI  - The achievement of comprehensive control targets among type 2 diabetes mellitus 
      patients of different ages.
PG  - 14066-14079
LID - 10.18632/aging.103358 [doi]
AB  - OBJECTIVE: To evaluate achievement of comprehensive controls among patients with 
      type 2 diabetes mellitus (T2DM) in different age groups. RESULTS: The elderly 
      patients had higher control rates for BMI (44.36%), TC (50.83%) and LDL-C 
      (48.27%) than those aged 60-80 years and younger patients (all P <0.05). Multiple 
      logistic regression revealed that elderly patients were more likely to achieve 
      control targets for HbA1c (odd ratio (OR) = 2.19), TC (OR = 1.32), HDL-C (OR = 
      1.35), and TG (OR = 1.74) than younger patients. This effect was stronger in 
      males (OR(HbA1c) = 2.27; OR(TC) = 1.41; OR(HDL-C) = 1.51; OR(TG) = 1.80). By 
      contrast, elderly females were only more likely to achieve HbA1c < 7.0% 
      (OR=1.88). CONCLUSIONS: Our findings suggest that comprehensive control 
      strategies still should be strengthened. METHODS: A total of 3126 T2DM patients 
      were included, and detected blood pressure (BP), body mass index (BMI), 
      glycosylated hemoglobin (HbA1c), fasting plasma glucose (FPG), postprandial 
      plasma glucose (PPG), total cholesterol (TC), low density lipoprotein cholesterol 
      (LDL-C), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C). We 
      divided patients into three age groups (<60, 60-80 and >/= 80 years), to assess the 
      differences in achieving the control targets.
FAU - Yu, Yun
AU  - Yu Y
AD  - Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical 
      University, Nanjing, China.
AD  - Division of Geriatrics, Drum Tower Clinical Medical College of Nanjing Medical 
      University, Nanjing, China.
FAU - Xie, Kaipeng
AU  - Xie K
AD  - Nanjing Maternity and Child Health Care Institute, Nanjing Maternity and Child 
      Health Care Hospital, Women's Hospital of Nanjing Medical University, Nanjing, 
      China.
FAU - Lou, Qinglin
AU  - Lou Q
AD  - Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Xia, Hui
AU  - Xia H
AD  - Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Wu, Dan
AU  - Wu D
AD  - Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Dai, Lingli
AU  - Dai L
AD  - Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Hu, Cuining
AU  - Hu C
AD  - Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Wang, Kunlin
AU  - Wang K
AD  - Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Shan, Shan
AU  - Shan S
AD  - Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Hu, Yun
AU  - Hu Y
AD  - Division of Geriatrics, Drum Tower Clinical Medical College of Nanjing Medical 
      University, Nanjing, China.
FAU - Tang, Wei
AU  - Tang W
AD  - Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical 
      University, Nanjing, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200722
PL  - United States
TA  - Aging (Albany NY)
JT  - Aging
JID - 101508617
RN  - 0 (Blood Glucose)
RN  - 0 (Cholesterol, HDL)
RN  - 0 (Glycated Hemoglobin A)
RN  - 0 (Triglycerides)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - *Aging
MH  - Blood Glucose/analysis
MH  - Cholesterol, HDL/blood
MH  - Diabetes Mellitus, Type 2/*drug therapy
MH  - Female
MH  - Glycated Hemoglobin/analysis
MH  - Glycemic Control/*methods
MH  - Goals
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Sex Characteristics
MH  - Triglycerides/blood
PMC - PMC7425513
OTO - NOTNLM
OT  - achievement
OT  - age
OT  - comprehensive target control
OT  - type 2 diabetes mellitus
COIS- CONFLICTS OF INTEREST: The authors declare that they have no conflicts of 
      interest.
EDAT- 2020/07/24 06:00
MHDA- 2021/03/25 06:00
PMCR- 2020/07/31
CRDT- 2020/07/24 06:00
PHST- 2019/11/06 00:00 [received]
PHST- 2020/05/20 00:00 [accepted]
PHST- 2020/07/24 06:00 [pubmed]
PHST- 2021/03/25 06:00 [medline]
PHST- 2020/07/24 06:00 [entrez]
PHST- 2020/07/31 00:00 [pmc-release]
AID - 103358 [pii]
AID - 10.18632/aging.103358 [doi]
PST - ppublish
SO  - Aging (Albany NY). 2020 Jul 22;12(14):14066-14079. doi: 10.18632/aging.103358. 
      Epub 2020 Jul 22.