PMID- 32699658 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200928 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 12 IP - 6 DP - 2020 Jun 17 TI - Factors Associated With Health-Related Quality of Life in Patients With Diabetic Foot Ulcer: A Cross-Sectional Study From Saudi Arabia. PG - e8658 LID - 10.7759/cureus.8658 [doi] LID - e8658 AB - Background and objective Diabetic foot ulcers (DFU) have been shown to have a high impact on the patients' perceived health-related quality of life (HRQOL). The aim of this study was to estimate the HRQOL and its related risk factors in patients with foot ulcers associated with type 2 diabetes mellitus (T2DM). Methods This cross-sectional study was performed on 81 patients with DFU, from January 2019 to July 2019 at the Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia. The study population was purposively and conveniently chosen based on patients' availability during their regular and customary outpatient clinic visits. Using the Arabic version of the Short-Form 36-Item Survey (SF-36), these patients were interviewed and their HRQOL scores were was assessed. The SF-36 covered eight aspects of health such as physical functioning, body pain, limitations in the roles induced by physical health problems, limitations in the roles caused by personal or emotional problems, emotional well-being, social functioning, energy/fatigue, and general health perceptions. Results It was evident that age, gender, education, occupation, smoking, duration of diabetes, hypertension, dyslipidemia, body mass index (BMI), and the number of diabetes-associated complications, hypertension, and dyslipidemia significantly affected the patients' physical functions. The physical health of the patient was strongly influenced by gender, education, occupation, income, BMI, and the number of complications. The emotional health of the patient was affected by dyslipidemia, deformity, prior amputations, as well as BMI and glycosylated hemoglobin (HbA1c). The social standing of the patient was influenced by age, income, education, and occupation. The degree of pain experienced by the patient varied with age and the number of complications, as well as notable differences in their general health. The factors of age, education, occupation, income, and the number of diabetic complications induced several health changes in varying degrees. The patients with DFU revealed overall lower HRQOL relating to all the eight aspects of the SF-36. Conclusion The patients with DFU in Saudi Arabia generally revealed lower HRQOL. However, prospective and large-scale studies are required in the future to support these findings. CI - Copyright (c) 2020, Al Ayed et al. FAU - Al Ayed, Mousab AU - Al Ayed M AD - Department of Endocrinology and Diabetes, Prince Sultan Military Medical City, Riyadh, SAU. FAU - Ababneh, Mutasem AU - Ababneh M AD - Department of Endocrinology and Diabetes, Prince Sultan Military Medical City, Riyadh, SAU. FAU - Alwin Robert, Asirvatham AU - Alwin Robert A AD - Department of Endocrinology and Diabetes, Prince Sultan Military Medical City, Riyadh, SAU. FAU - Al Misfer, Nasser AU - Al Misfer N AD - Department of Physical Therapy, Prince Sultan Military Medical City, Riyadh, SAU. FAU - Cruz, Maria AU - Cruz M AD - Department of Endocrinology and Diabetes, Prince Sultan Military Medical City, Riyadh, SAU. FAU - Austria, Hesiel C AU - Austria HC AD - Department of Endocrinology and Diabetes, Prince Sultan Military Medical City, Riyadh, SAU. FAU - Al Dawish, Mohamed AU - Al Dawish M AD - Department of Endocrinology and Diabetes, Prince Sultan Military Medical City, Riyadh, SAU. LA - eng PT - Journal Article DEP - 20200617 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC7370698 OTO - NOTNLM OT - diabetic foot ulcer OT - emotional well-being OT - general health OT - quality of life COIS- The authors have declared that no competing interests exist. EDAT- 2020/07/24 06:00 MHDA- 2020/07/24 06:01 PMCR- 2020/06/17 CRDT- 2020/07/24 06:00 PHST- 2020/07/24 06:00 [entrez] PHST- 2020/07/24 06:00 [pubmed] PHST- 2020/07/24 06:01 [medline] PHST- 2020/06/17 00:00 [pmc-release] AID - 10.7759/cureus.8658 [doi] PST - epublish SO - Cureus. 2020 Jun 17;12(6):e8658. doi: 10.7759/cureus.8658.