PMID- 32702595
OWN - NLM
STAT- MEDLINE
DCOM- 20210111
LR  - 20210111
IS  - 1873-6750 (Electronic)
IS  - 0160-4120 (Linking)
VI  - 143
DP  - 2020 Oct
TI  - Greenness surrounding schools is associated with lower risk of asthma in 
      schoolchildren.
PG  - 105967
LID - S0160-4120(20)31922-X [pii]
LID - 10.1016/j.envint.2020.105967 [doi]
AB  - BACKGROUND: There is increasing interest in the effect of residential greenness 
      on respiratory health in children with inconsistent results. However, there are 
      no studies investigating the association between greenness around schools, a 
      representative environment for children and childhood asthma. OBJECTIVES: To 
      investigate the association between greenness surrounding schools and asthma in 
      schoolchildren. METHODS: We recruited 59,754 schoolchildren from 94 schools in 
      2012-2013 from the Seven Northeast Cities Study, China. Greenness surrounding 
      schools was measured using the normalized difference vegetation index (NDVI) and 
      soil adjusted vegetation index (SAVI) at buffers from 30 to 1000 m. Asthma 
      symptoms were collected from validated self-reported questionnaires. Logistic 
      mixed-effects regression models were used to estimate the associations between 
      greenness surrounding school and childhood asthma after adjustment for 
      covariates. RESULTS: We found that greenness surrounding schools in all buffered 
      sizes was negatively associated with the prevalence of asthmatic symptoms in 
      schoolchildren. A 0.1-unit increase in NDVI(1000m) was associated with lower odds 
      of current asthma (odds ratio: 0.81, 95% confidential interval: 0.75, 0.86) and 
      current wheeze (OR: 0.89, 95% CI: 0.84, 0.94) in children after covariate 
      adjustments. Higher greenness was associated with less asthma symptoms in a 
      dose-response pattern (P for trend < 0.05). The estimated associations appeared 
      to be stronger in children exposure to higher air pollution level. The observed 
      associations varied across seven cities. CONCLUSION: Our findings suggest 
      beneficial associations of greenness surrounding schools with childhood asthma. 
      Further studies are needed to confirm our results.
CI  - Copyright (c) 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.
FAU - Zeng, Xiao-Wen
AU  - Zeng XW
AD  - Department of Occupational and Environmental Health, School of Public Health, Sun 
      Yat-sen University, Guangzhou 510080, China; Allergy and Lung Health Unit, Centre 
      for Epidemiology and Biostatistics, Melbourne School of Population & Global 
      Health, The University of Melbourne, VIC 3052, Australia.
FAU - Lowe, Adrian J
AU  - Lowe AJ
AD  - Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, 
      Melbourne School of Population & Global Health, The University of Melbourne, VIC 
      3052, Australia.
FAU - Lodge, Caroline J
AU  - Lodge CJ
AD  - Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, 
      Melbourne School of Population & Global Health, The University of Melbourne, VIC 
      3052, Australia.
FAU - Heinrich, Joachim
AU  - Heinrich J
AD  - Institute of Epidemiology, Helmholtz Zentrum Munchen - German Research Center for 
      Environmental Health, Munich 80336, Germany; Institute and Outpatient Clinic for 
      Occupational, Social and Environmental Medicine, University Hospital Munich, 
      Ludwig Maximilian University, Munich 80336, Germany.
FAU - Roponen, Marjut
AU  - Roponen M
AD  - Department of Environmental and Biological Sciences, University of Eastern 
      Finland, Kuopio 70211, Finland.
FAU - Jalava, Pasi
AU  - Jalava P
AD  - Department of Environmental and Biological Sciences, University of Eastern 
      Finland, Kuopio 70211, Finland.
FAU - Guo, Yuming
AU  - Guo Y
AD  - Department of Epidemiology and Preventive Medicine, School of Public Health and 
      Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia.
FAU - Hu, Li-Wen
AU  - Hu LW
AD  - Department of Occupational and Environmental Health, School of Public Health, Sun 
      Yat-sen University, Guangzhou 510080, China.
FAU - Yang, Bo-Yi
AU  - Yang BY
AD  - Department of Occupational and Environmental Health, School of Public Health, Sun 
      Yat-sen University, Guangzhou 510080, China.
FAU - Dharmage, Shyamali C
AU  - Dharmage SC
AD  - Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, 
      Melbourne School of Population & Global Health, The University of Melbourne, VIC 
      3052, Australia.
FAU - Dong, Guang-Hui
AU  - Dong GH
AD  - Department of Occupational and Environmental Health, School of Public Health, Sun 
      Yat-sen University, Guangzhou 510080, China. Electronic address: 
      donggh5@mail.sysu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200721
PL  - Netherlands
TA  - Environ Int
JT  - Environment international
JID - 7807270
SB  - IM
MH  - *Air Pollution/adverse effects/analysis
MH  - *Asthma/epidemiology
MH  - Child
MH  - China/epidemiology
MH  - Cities
MH  - Humans
MH  - Schools
OTO - NOTNLM
OT  - Asthma
OT  - Children
OT  - Greenness
OT  - School
EDAT- 2020/07/24 06:00
MHDA- 2021/01/12 06:00
CRDT- 2020/07/24 06:00
PHST- 2020/03/26 00:00 [received]
PHST- 2020/07/05 00:00 [revised]
PHST- 2020/07/08 00:00 [accepted]
PHST- 2020/07/24 06:00 [pubmed]
PHST- 2021/01/12 06:00 [medline]
PHST- 2020/07/24 06:00 [entrez]
AID - S0160-4120(20)31922-X [pii]
AID - 10.1016/j.envint.2020.105967 [doi]
PST - ppublish
SO  - Environ Int. 2020 Oct;143:105967. doi: 10.1016/j.envint.2020.105967. Epub 2020 
      Jul 21.