PMID- 32709321
OWN - NLM
STAT- MEDLINE
DCOM- 20200825
LR  - 20200825
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1625
DP  - 2020 Aug 16
TI  - Fluoro-functionalized stationary phases for electrochromatographic separation of 
      organic fluorides.
PG  - 461269
LID - S0021-9673(20)30547-1 [pii]
LID - 10.1016/j.chroma.2020.461269 [doi]
AB  - Fluorous affinity means remarkably specific interaction between highly organic 
      fluorides. This work aims to explore the potential of fluoro-functionalized 
      stationary phase for the separation of organic fluorides by means of 
      fluorous-fluorous interaction. Here, by using the Michael addition strategy 
      between 1H,1H,2H,2H-perfluorodecanethiol (PFDT) and polydopamine (PD), a novel 
      fluoro-functionalized stationary phase was synthesized for open-tubular capillary 
      electrochromatography (OT-CEC). The PFDT@PD was characterized by scanning 
      electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR) and 
      X-ray Photoelectron Spectrometer (XPS). The PFDT@PD@capillary exhibited 
      outstanding separation performance towards neutral compounds (such as 
      alkylbenzenes and chlorobenzenes) and organic fluorides (such as fluorobenzenes 
      and perfluoroalkyl methacrylates etc.) with high resolution and high separation 
      efficiency by hydrophobic interaction and fluorous-fluorous interaction. In 
      addition, the column shows good stability and reproducibility. The relative 
      standard deviations (RSDs) of the retention time for intra-day (n = 5) and 
      inter-day (n = 3) runs and between columns (n = 3) are less than 0.39%, 1.22% and 
      3.87%, respectively. This novel type of fluoro-functionalized stationary phase 
      represents a great application potential in organic fluorides separation field.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Li, Zhentao
AU  - Li Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of 
      Education Hubei Province Engineering and Technology Research Center for 
      Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, 
      Wuhan, 430071, China; State Key Laboratory of Transducer Technology, Chinese 
      Academy of Sciences, Beijing 10080, China.
FAU - Mao, Zhenkun
AU  - Mao Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of 
      Education Hubei Province Engineering and Technology Research Center for 
      Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, 
      Wuhan, 430071, China.
FAU - Hu, Changjun
AU  - Hu C
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of 
      Education Hubei Province Engineering and Technology Research Center for 
      Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, 
      Wuhan, 430071, China.
FAU - Li, Qiaoyan
AU  - Li Q
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of 
      Education Hubei Province Engineering and Technology Research Center for 
      Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, 
      Wuhan, 430071, China.
FAU - Chen, Zilin
AU  - Chen Z
AD  - Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of 
      Education Hubei Province Engineering and Technology Research Center for 
      Fluorinated Pharmaceuticals, Wuhan University School of Pharmaceutical Sciences, 
      Wuhan, 430071, China; State Key Laboratory of Transducer Technology, Chinese 
      Academy of Sciences, Beijing 10080, China. Electronic address: chenzl@whu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20200528
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Indoles)
RN  - 0 (Organic Chemicals)
RN  - 0 (Parabens)
RN  - 0 (Polymers)
RN  - 0 (polydopamine)
RN  - 284SYP0193 (Fluorine)
RN  - Q80VPU408O (Fluorides)
SB  - IM
MH  - Capillary Electrochromatography/*methods
MH  - Electroosmosis
MH  - Fluorides/*isolation & purification
MH  - Fluorine/*chemistry
MH  - Indoles/chemistry
MH  - Organic Chemicals/*isolation & purification
MH  - Parabens/analysis/chemistry
MH  - Polymers/chemistry
MH  - Reproducibility of Results
MH  - Spectroscopy, Fourier Transform Infrared
OTO - NOTNLM
OT  - Electrochromatography
OT  - Fluoro-functionalized
OT  - Fluorous affinity
OT  - Open-tubular column
OT  - Organic fluorides
COIS- Declaration of Competing Interest Authors declare no conflict of interest
EDAT- 2020/07/28 06:00
MHDA- 2020/08/26 06:00
CRDT- 2020/07/26 06:00
PHST- 2020/04/19 00:00 [received]
PHST- 2020/05/19 00:00 [revised]
PHST- 2020/05/20 00:00 [accepted]
PHST- 2020/07/26 06:00 [entrez]
PHST- 2020/07/28 06:00 [pubmed]
PHST- 2020/08/26 06:00 [medline]
AID - S0021-9673(20)30547-1 [pii]
AID - 10.1016/j.chroma.2020.461269 [doi]
PST - ppublish
SO  - J Chromatogr A. 2020 Aug 16;1625:461269. doi: 10.1016/j.chroma.2020.461269. Epub 
      2020 May 28.