PMID- 32709334
OWN - NLM
STAT- MEDLINE
DCOM- 20200908
LR  - 20200908
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1625
DP  - 2020 Aug 16
TI  - Rapid preparation and evaluation of chiral open-tubular columns supported with 
      bovine serum album and zeolite imidazolate framework-8 for mini-capillary 
      electrochromatography.
PG  - 461284
LID - S0021-9673(20)30562-8 [pii]
LID - 10.1016/j.chroma.2020.461284 [doi]
AB  - In this work, a class of novel and eco-friendly open-tubular (OT) chiral column 
      was presented for the first time by one step preparation with zeolite imidazolate 
      framework-8 (ZIF-8) and bovine serum album (BSA) based on electrostatic 
      adsorption and adsorption affinity. This stationary phase materials combined the 
      features of large surface areas and adsorption affinity of ZIF-8, and also the 
      multiple chiral binding sites of BSA, which contributes to the pi-interaction and 
      hydrophobic interaction with the analytes. The separation performance of 
      BSA@ZIF-8-OT chiral columns was evaluated with a miniaturized capillary 
      electrochromatography and amperometric detection (mini-CEC-AD) system; in 
      particular, nine groups of model molecules, including homologues, structural 
      isomers, and chiral compounds, were baseline separated under the certain optimum 
      conditions. The RSDs of run-to-run, day-to-day, column-to-column, and 
      batch-to-batch reproducibility were less than 13.8 %. Furthermore, the prepared 
      OT columns were successfully applied to fast analysis of ephedrine isomers in 
      Chinese herb ephedra, and the LODs achieved 1.5-2.0 ng mL(-1) (S/N=3) by an 
      electrophoretic stacking technique of moving chemical reaction boundary. This 
      mini-CEC-AD system with BSA@ZIF-8-OT chiral columns provides a promising 
      potential in pharmaceutical analysis due to its fast, sensitive, 
      enantioselective, and low-cost characteristics.
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Wang, Tingting
AU  - Wang T
AD  - School of Chemistry and Molecular Engineering, East China Normal University, 
      Shanghai 200241, China.
FAU - Wang, Ying
AU  - Wang Y
AD  - School of Chemistry and Molecular Engineering, East China Normal University, 
      Shanghai 200241, China.
FAU - Zhang, Yulian
AU  - Zhang Y
AD  - School of Chemistry and Molecular Engineering, East China Normal University, 
      Shanghai 200241, China.
FAU - Cheng, Yuhuan
AU  - Cheng Y
AD  - School of Chemistry and Molecular Engineering, East China Normal University, 
      Shanghai 200241, China.
FAU - Ye, Jiannong
AU  - Ye J
AD  - School of Chemistry and Molecular Engineering, East China Normal University, 
      Shanghai 200241, China.
FAU - Chu, Qingcui
AU  - Chu Q
AD  - School of Chemistry and Molecular Engineering, East China Normal University, 
      Shanghai 200241, China. Electronic address: qcchu@chem.ecnu.edu.cn.
FAU - Cheng, Guifang
AU  - Cheng G
AD  - School of Chemistry and Molecular Engineering, East China Normal University, 
      Shanghai 200241, China.
LA  - eng
PT  - Journal Article
DEP - 20200531
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Imidazoles)
RN  - 0 (acidified zeolitic imidazolate framework-8)
RN  - 1318-02-1 (Zeolites)
RN  - 27432CM55Q (Serum Albumin, Bovine)
SB  - IM
MH  - Adsorption
MH  - Animals
MH  - Capillary Electrochromatography/*methods
MH  - Cattle
MH  - Hydrogen-Ion Concentration
MH  - Imidazoles/*chemistry
MH  - Limit of Detection
MH  - Reproducibility of Results
MH  - Serum Albumin, Bovine/*chemistry
MH  - Stereoisomerism
MH  - Zeolites/*chemistry
OTO - NOTNLM
OT  - Chiral open-tubular column
OT  - amperometric detection
OT  - bovine serum album
OT  - mini-capillary electrochromatography
OT  - pharmaceutical analysis
OT  - zeolite imidazolate framework-8
COIS- Declaration of competing interest None.
EDAT- 2020/07/28 06:00
MHDA- 2020/09/09 06:00
CRDT- 2020/07/26 06:00
PHST- 2020/03/18 00:00 [received]
PHST- 2020/05/24 00:00 [revised]
PHST- 2020/05/27 00:00 [accepted]
PHST- 2020/07/26 06:00 [entrez]
PHST- 2020/07/28 06:00 [pubmed]
PHST- 2020/09/09 06:00 [medline]
AID - S0021-9673(20)30562-8 [pii]
AID - 10.1016/j.chroma.2020.461284 [doi]
PST - ppublish
SO  - J Chromatogr A. 2020 Aug 16;1625:461284. doi: 10.1016/j.chroma.2020.461284. Epub 
      2020 May 31.