PMID- 32710511 OWN - NLM STAT- MEDLINE DCOM- 20210621 LR - 20210621 IS - 2055-5822 (Electronic) IS - 2055-5822 (Linking) VI - 7 IP - 5 DP - 2020 Oct TI - Compression therapy for leg oedema in patients with heart failure. PG - 2012-2020 LID - 10.1002/ehf2.12848 [doi] AB - The presence of chronic heart failure (CHF) results in a significant risk of leg oedema. Medical compression (MC) treatment is one of the basic methods of leg oedema elimination in patients with chronic venous disease and lymphedema, but it is not routinely considered in subjects with CHF-related swelling. In the study, an overview of the current knowledge related to the benefits and risk of using MC in the supportive treatment of leg oedema in CHF patients is presented. The available studies dedicated the comprehensive management of leg swelling using MC in CHF patients published in the English language literature till December 2019 were evaluated in term of the treatment efficacy and safety. In studies performed on CHF populations, manual lymphatic drainage, MC stocking, multilayer bandaged, as well as intermittent pneumatic compression or electric calf stimulations were used. The current evidence is based on non-randomized studies, small study cohorts, as well as very heterogenous populations. The use of the intermittent pneumatic compression in CHF patients significantly increases the right auricular pressure and mean pulmonary artery pressures as well as decreases systemic vascular resistance in most patients without the clinical worsening. The transient and rapid increase in the human atrial natriuretic peptide, after an application of the MC stocking in New York Heart Association (NYHA) class II patients was observed without clinical exacerbation. An application of the multilayer bandages in NYHA classes III and IV patients lead a significant increase in the right arterial pressure and lead to transient deterioration of the right and the left ventricular functions. In the manual lymphatic drainage study, aside from expected leg circumference reduction, no clinical worsening was observed. In a pilot study performed in a small cohort of CHF patients, electrical calf stimulation use resulted in a reduction in the lean mass of the legs without cardiac function worsening. The use of local leg compression can be considered stable CHF patients without decompensated heart function for both CHF-related oedema treatment and for treatment of the concomitant diseases leading to leg swelling occurrence. The use of MC in more severe classes of CHF (NYHA III and IV) should be the subject of future clinical studies to select the safest and most efficient compression method as well as to select the patients who benefit most from this kind of treatment. CI - (c) 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology. FAU - Urbanek, Tomasz AU - Urbanek T AD - Department of General Surgery, Vascular Surgery, Angiology and Phlebology, Medical University of Silesia, Katowice, Poland. FAU - Jusko, Maciej AU - Jusko M AD - Department of General Surgery, Vascular Surgery, Angiology and Phlebology, Medical University of Silesia, Katowice, Poland. FAU - Kuczmik, Waclaw B AU - Kuczmik WB AD - Department of General Surgery, Vascular Surgery, Angiology and Phlebology, Medical University of Silesia, Katowice, Poland. LA - eng PT - Journal Article PT - Review DEP - 20200725 PL - England TA - ESC Heart Fail JT - ESC heart failure JID - 101669191 SB - IM MH - Edema/etiology/therapy MH - *Heart Failure/complications/therapy MH - Humans MH - *Leg MH - Pilot Projects MH - Pressure PMC - PMC7524111 OTO - NOTNLM OT - Heart failure OT - Leg swelling OT - Lymphedema OT - Medical compression EDAT- 2020/07/28 06:00 MHDA- 2021/06/22 06:00 PMCR- 2020/07/25 CRDT- 2020/07/26 06:00 PHST- 2020/04/08 00:00 [received] PHST- 2020/05/16 00:00 [revised] PHST- 2020/06/02 00:00 [accepted] PHST- 2020/07/28 06:00 [pubmed] PHST- 2021/06/22 06:00 [medline] PHST- 2020/07/26 06:00 [entrez] PHST- 2020/07/25 00:00 [pmc-release] AID - EHF212848 [pii] AID - 10.1002/ehf2.12848 [doi] PST - ppublish SO - ESC Heart Fail. 2020 Oct;7(5):2012-2020. doi: 10.1002/ehf2.12848. Epub 2020 Jul 25.