PMID- 32711463
OWN - NLM
STAT- MEDLINE
DCOM- 20210111
LR  - 20210111
IS  - 1471-2261 (Electronic)
IS  - 1471-2261 (Linking)
VI  - 20
IP  - 1
DP  - 2020 Jul 25
TI  - Risk factors of embolism for the cardiac myxoma patients: a systematic review and 
      metanalysis.
PG  - 348
LID - 10.1186/s12872-020-01631-w [doi]
LID - 348
AB  - BACKGROUND: The risk factors contributing to embolism in cardiac myxoma (CM) are 
      yet controversial. This systematic review and meta-analysis aimed to clarify the 
      risk factors of embolism for the CM patients. METHODS: PubMed, Embase, Cochrane 
      library, Web of Science, China National Knowledge Infrastructure, Wan Fang, and 
      Wei Pu databases were searched from inception to June 2019. Statistical analysis 
      was conducted using Stata version 14.0. The pooled odds ratio or mean difference 
      with 95% confidence interval was estimated for each risk factor. RESULTS: Herein, 
      12 studies, encompassing 1814 patients, were included. The pooled results 
      suggested that New York Heart Association (NYHA) class I/II (P < 0.01), 
      hypertension (P = 0.03), irregular tumor surface (P < 0.01), tumor in atypical 
      location (P = 0.01), narrow base of tumor (P < 0.01), and increased fibrinogen 
      (FIB) (P < 0.01) are significant risk factors of embolism in CM patients. 
      However, sex, age, body mass index, smoking, left ventricular ejection fraction, 
      diabetes, hyperlipidemia, atrial fibrillation, valvular heart disease, coronary 
      heart disease, tumor size, platelet count, white blood cells, and hemoglobin were 
      not associated with embolism (all P > 0.05). CONCLUSIONS: NYHA class (I/II), 
      hypertension, irregular tumor surface, atypical tumor location, the narrow base 
      of tumor, and increased FIB were significant risk factors of embolism in CM 
      patients. For CM patients with these factors, early surgery might be beneficial 
      to prevent embolism.
FAU - Liu, Yanna
AU  - Liu Y
AD  - Department of Ultrasound, The Second Affiliated Hospital of Nanchang University, 
      Minde Road No.1, Nanchang, 330006, Jiangxi, China.
FAU - Wang, Jiwei
AU  - Wang J
AD  - Department of Ultrasound, The Second Affiliated Hospital of Nanchang University, 
      Minde Road No.1, Nanchang, 330006, Jiangxi, China.
FAU - Guo, Liangyun
AU  - Guo L
AD  - Department of Ultrasound, The Second Affiliated Hospital of Nanchang University, 
      Minde Road No.1, Nanchang, 330006, Jiangxi, China.
FAU - Ping, Luyi
AU  - Ping L
AUID- ORCID: 0000-0001-5661-3074
AD  - Department of Ultrasound, The Second Affiliated Hospital of Nanchang University, 
      Minde Road No.1, Nanchang, 330006, Jiangxi, China. 939684026@qq.com.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
DEP - 20200725
PL  - England
TA  - BMC Cardiovasc Disord
JT  - BMC cardiovascular disorders
JID - 100968539
RN  - 0 (Biomarkers)
RN  - 9001-32-5 (Fibrinogen)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Biomarkers/blood
MH  - Embolism/diagnosis/*etiology
MH  - Female
MH  - Fibrinogen/analysis
MH  - Heart Neoplasms/*complications/pathology
MH  - Humans
MH  - Hypertension/complications
MH  - Male
MH  - Middle Aged
MH  - Myxoma/*complications/pathology
MH  - Prognosis
MH  - Risk Assessment
MH  - Risk Factors
MH  - Up-Regulation
PMC - PMC7382866
OTO - NOTNLM
OT  - Cardiac myxoma
OT  - Embolism
OT  - Meta-analysis
OT  - Risk factors
COIS- The authors declare that they have no competing interests.
EDAT- 2020/07/28 06:00
MHDA- 2021/01/12 06:00
PMCR- 2020/07/25
CRDT- 2020/07/27 06:00
PHST- 2019/11/23 00:00 [received]
PHST- 2020/07/20 00:00 [accepted]
PHST- 2020/07/27 06:00 [entrez]
PHST- 2020/07/28 06:00 [pubmed]
PHST- 2021/01/12 06:00 [medline]
PHST- 2020/07/25 00:00 [pmc-release]
AID - 10.1186/s12872-020-01631-w [pii]
AID - 1631 [pii]
AID - 10.1186/s12872-020-01631-w [doi]
PST - epublish
SO  - BMC Cardiovasc Disord. 2020 Jul 25;20(1):348. doi: 10.1186/s12872-020-01631-w.