PMID- 32718136 OWN - NLM STAT- MEDLINE DCOM- 20201224 LR - 20220415 IS - 2980-3187 (Electronic) IS - 0494-1373 (Linking) VI - 68 IP - 1 DP - 2020 Mar TI - Real life results of coil treatment for bronchoscopic lung volume reduction in emphysema. PG - 17-24 LID - 10.5578/tt.69320 [doi] AB - INTRODUCTION: The lung volume reduction coil treatment is a minimally invasive bronchoscopic treatment option for emphysema patients who suffer from severe hyperinflation. Previous studies have reported successful outcomes in selected cases using coil for bronchoscopic lung volume reduction (BLVR). Our aim is to determine the changes in respiratory function tests, perception of dyspnea and exercise capacities after 12 months in patients treated with endobronchial coil. MATERIALS AND METHODS: The data of patients with severe emphysema and treated with coils between 2014-2017 were evaluated retrospectively. Dynamic and static lung volume capacities at baseline and 12 months, modified Medical Research Council (mMRC) questionnaire and six-minute walk test (6-MWT) results were recorded. RESULT: BLVR was performed in thirty patients (one female, twenty-nine males). Five patients were treated bilaterally and twentyfive unilaterally. One patient died after 7 days and 4 patients died during follow-up. Five patients were lost to follow-up. A total of twenty patients with available data were included in the study. A statistically significant difference was found in mMRC results in pre-treatment and 12-month evaluations. There was no significant difference in FEV1, TLC and RV values at the end of 12 months. There was an increase of 18.9 meters (+/- 83.5 m) between the baseline and 12 months in 6-MWT. 45% of the patients improved their walking distance over 26 meters which is known as minimal clinically important difference (MCID). CONCLUSIONS: Although no significant changes were observed in pulmonary function tests and lung volumes, the increase in exercise capacity and decreased perception of dyspnea indicate the efficacy of endobronchial coil. FAU - Turan, Demet AU - Turan D AD - Clinic of Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Dogan, Deniz AU - Dogan D AD - Department of Chest Diseases, Faculty of Gulhane Medicine, Health Sciences University, Ankara, Turkey. FAU - Cortuk, Mustafa AU - Cortuk M AD - Clinic of Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Ugur Chousein, Efsun Gonca AU - Ugur Chousein EG AD - Clinic of Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Tanriverdi, Elif AU - Tanriverdi E AD - Clinic of Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Yildirim, Binnaz Zeynep AU - Yildirim BZ AD - Clinic of Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Demirkol, Baris AU - Demirkol B AD - Clinic of Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Cinarka, Halit AU - Cinarka H AD - Clinic of Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Ozgul, Mehmet Akif AU - Ozgul MA AD - Clinic of Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. FAU - Cetinkaya, Erdogan AU - Cetinkaya E AD - Clinic of Chest Diseases, Yedikule Chest Diseases and Chest Surgery Training and Research Hospital, Istanbul, Turkey. LA - eng PT - Journal Article TT - Amfizemli hastalarin bronkoskopik volum azaltici coil tedavisinin gercek yasam sonuclari. PL - Turkey TA - Tuberk Toraks JT - Tuberkuloz ve toraks JID - 0417364 SB - IM MH - Bronchoscopy/*methods MH - Dyspnea/etiology MH - Female MH - Forced Expiratory Volume MH - Humans MH - Male MH - Middle Aged MH - Pneumonectomy/*methods MH - Pulmonary Emphysema/complications/physiopathology/*surgery MH - Respiratory Function Tests/methods MH - Retrospective Studies MH - Severity of Illness Index MH - Treatment Outcome EDAT- 2020/07/29 06:00 MHDA- 2020/12/29 06:00 CRDT- 2020/07/29 06:00 PHST- 2020/07/29 06:00 [entrez] PHST- 2020/07/29 06:00 [pubmed] PHST- 2020/12/29 06:00 [medline] AID - 10.5578/tt.69320 [doi] PST - ppublish SO - Tuberk Toraks. 2020 Mar;68(1):17-24. doi: 10.5578/tt.69320.