PMID- 32727305
OWN - NLM
STAT- MEDLINE
DCOM- 20211105
LR  - 20220427
IS  - 1784-973X (Electronic)
IS  - 0001-5385 (Linking)
VI  - 76
IP  - 8
DP  - 2021 Oct
TI  - Impact of COVID-19-related public containment measures on the ST elevation 
      myocardial infarction epidemic in Belgium: a nationwide, serial, cross-sectional 
      study.
PG  - 863-869
LID - 10.1080/00015385.2020.1796035 [doi]
AB  - AIMS: The current study assessed the impact of COVID-19-related public 
      containment measures (i.e. lockdown) on the ST elevation myocardial infarction 
      (STEMI) epidemic in Belgium. METHODS AND RESULTS: Clinical characteristics, 
      reperfusion therapy modalities, COVID-19 status and in-hospital mortality of 
      consecutive STEMI patients who were admitted to Belgian hospitals for 
      percutaneous coronary intervention (PCI) were recorded during a three-week period 
      starting at the beginning of the lockdown period on 13 March 2020. Similar data 
      were collected for the same time period for 2017-2019. An evaluation of air 
      quality revealed a 32% decrease in ambient NO(2) concentrations during lockdown 
      (19.5 microg/m(3) versus 13.2 microg/m(3), p < .001). During the three-week period, there 
      were 188 STEMI patients admitted for PCI during the lockdown versus an average 
      254 STEMI patients before the lockdown period (incidence rate ratio = 0.74, 
      p = .001). Reperfusion strategy was predominantly primary PCI in both time 
      periods (96% versus 95%). However, there was a significant delay in treatment 
      during the lockdown period, with more late presentations (>12 h after onset of 
      pain) (14% versus 7.6%, p = .04) and with longer door-to-balloon times (median of 
      45 versus 39 min, p = .02). Although the in-hospital mortality between the two 
      periods was comparable (5.9% versus 6.7%), 5 of the 7 (71%) COVID-19-positive 
      STEMI patients died. CONCLUSION: The present study revealed a 26% reduction in 
      STEMI admissions and a delay in treatment of STEMI patients. Less exposure to 
      external STEMI triggers (such as ambient air pollution) and/or reluctance to seek 
      medical care are possible explanations of this observation.
FAU - Claeys, Marc J
AU  - Claeys MJ
AUID- ORCID: 0000-0002-6628-9543
AD  - Department of Cardiology, University Hospital Antwerp, Antwerp, Belgium.
FAU - Argacha, Jean-Francois
AU  - Argacha JF
AD  - Department of Cardiology, University Hospital Brussels, Brussels, Belgium.
FAU - Collart, Philippe
AU  - Collart P
AD  - Centre de recherche en Epidemiologie, Biostatistiques et Recherche Clinique, 
      School of Public Health, Universite Libre de Bruxelles, Brussels, Belgium.
FAU - Carlier, Marc
AU  - Carlier M
AD  - Department of Cardiology, GHDC, Charleroi, Belgium.
FAU - Van Caenegem, Olivier
AU  - Van Caenegem O
AD  - Division of Cardiovascular Intensive Care, Cliniques universitaires Saint Luc, 
      Brussels, Belgium.
FAU - Sinnaeve, Peter R
AU  - Sinnaeve PR
AUID- ORCID: 0000-0003-4716-5892
AD  - Department of Cardiology, University Hospital Leuven, Leuven, Belgium.
FAU - Desmet, Walter
AU  - Desmet W
AD  - Department of Cardiology, University Hospital Leuven, Leuven, Belgium.
FAU - Dubois, Philippe
AU  - Dubois P
AD  - Department of Cardiology, CHU, Charleroi, Belgium.
FAU - Stammen, Francis
AU  - Stammen F
AD  - Department of Cardiology, Hospital Roeselare, Roeselare, Belgium.
FAU - Gevaert, Sofie
AU  - Gevaert S
AD  - Department of Cardiology, Ghent University Hospital, Ghent, Belgium.
FAU - Pourbaix, Suzanne
AU  - Pourbaix S
AD  - Department of Cardiology, CHR Citadelle Liege, Liege, Belgium.
FAU - Coussement, Patrick
AU  - Coussement P
AD  - Department of Cardiology, Hospital Sint-Jan Brugge, Brugge, Belgium.
FAU - Beauloye, Christophe
AU  - Beauloye C
AD  - Division of Cardiology and Pole of Cardiovascular Research, Institut de Recherche 
      Experimentale et Clinique, Cliniques universitaires Saint Luc, Brussels, Belgium.
FAU - Evrard, Patrick
AU  - Evrard P
AD  - Department of Intensive Care, Belgium Catholic University Hospital Mont-Godinne, 
      Brussels, Belgium.
FAU - Brasseur, Olivier
AU  - Brasseur O
AD  - Laboratory of Environmental Research, Brussels Environment, Brussels, Belgium.
FAU - Fierens, Frans
AU  - Fierens F
AD  - Belgian Interregional Environment Agency, Brussels, Belgium.
FAU - Marechal, Patrick
AU  - Marechal P
AD  - Department of Cardiology, University hospital of Liege, Liege, Belgium.
FAU - Schelfaut, Dan
AU  - Schelfaut D
AD  - Department of Cardiology, OLV Aalst, Aalst, Belgium.
FAU - Flore, Vincent
AU  - Flore V
AD  - Department of Cardiology, Hospital Maria Middelares, Ghent, Belgium.
FAU - Hanet, Claude
AU  - Hanet C
AD  - Department of Cardiology, Catholic University Hospital Mont-Godinne, Brussels, 
      Belgium.
LA  - eng
PT  - Journal Article
DEP - 20200730
PL  - England
TA  - Acta Cardiol
JT  - Acta cardiologica
JID - 0370570
SB  - IM
MH  - Belgium/epidemiology
MH  - *COVID-19/prevention & control
MH  - *Communicable Disease Control
MH  - Cross-Sectional Studies
MH  - *Epidemics
MH  - Humans
MH  - *Percutaneous Coronary Intervention
MH  - *ST Elevation Myocardial Infarction/diagnosis/epidemiology
OTO - NOTNLM
OT  - COVID-19
OT  - PCI
OT  - STEMI
OT  - containment
OT  - mortality
OT  - pollution
EDAT- 2020/07/31 06:00
MHDA- 2021/11/06 06:00
CRDT- 2020/07/31 06:00
PHST- 2020/07/31 06:00 [pubmed]
PHST- 2021/11/06 06:00 [medline]
PHST- 2020/07/31 06:00 [entrez]
AID - 10.1080/00015385.2020.1796035 [doi]
PST - ppublish
SO  - Acta Cardiol. 2021 Oct;76(8):863-869. doi: 10.1080/00015385.2020.1796035. Epub 
      2020 Jul 30.