PMID- 32733859
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2296-4185 (Print)
IS  - 2296-4185 (Electronic)
IS  - 2296-4185 (Linking)
VI  - 8
DP  - 2020
TI  - Characteristics of Harmonic Indexes of the Arterial Blood Pressure Waveform in 
      Type 2 Diabetes Mellitus.
PG  - 638
LID - 10.3389/fbioe.2020.00638 [doi]
LID - 638
AB  - Type 2 diabetes mellitus (T2DM) is an important public health issue worldwide. 
      T2DM correlates with cardiovascular disease. Arterial stiffness is also a key 
      factor that can be thought of as a surrogate marker. Nevertheless, it was unclear 
      which harmonic indexes of blood pressure waveforms (BPWs) from subjects' radial 
      artery pulses would be affected by T2DM. Therefore, the objective of this study 
      was to investigate whether and how harmonic indexes can be used to discriminate 
      hemodynamic differences between patients with T2DM and non-T2DM. This helps us to 
      build objective results no matter who conducts the examination instead of pulse 
      diagnosis in traditional way. We enrolled T2DM and non-T2DM patients as 
      experimental and control groups, respectively, from the Department of Family 
      Medicine in the National Taiwan University Hospital and the Department of 
      Internal Medicine in Taipei's Veterans General Hospital from December 2017 to 
      January 2019. ANSWatch(R) Model TS-0411 was used to capture the BPWs. Amplitude 
      proportions (C(n) values) were calculated from harmonics 1-10 of the BPW using 
      fast Fourier transform. Thirty-two T2DM and 15 non-T2DM patients were enrolled. 
      T2DM patients had significant differences in C(1) (p = 0.031) and C(5) (p = 
      0.041). The study suggests that analyzing the harmonic characteristics of 
      non-invasively measured BPW of radial artery may be a potential and 
      easy-to-perform approach to discriminate T2DM-induced hemodynamic changes.
CI  - Copyright (c) 2020 Liao, Tsai, Lin, Lee, Lai, Ho and Lai.
FAU - Liao, Chen-Kai
AU  - Liao CK
AD  - Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan 
      University, Taipei, Taiwan.
AD  - Lao De Yan Traditional Chinese Medicine Clinic, New Taipei City, Taiwan.
FAU - Tsai, Jaw-Shiun
AU  - Tsai JS
AD  - Department of Family Medicine, National Taiwan University Hospital, Taipei, 
      Taiwan.
FAU - Lin, Liang-Yu
AU  - Lin LY
AD  - Division of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans 
      General Hospital, Taipei, Taiwan.
AD  - Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan.
FAU - Lee, Si-Chen
AU  - Lee SC
AD  - Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan 
      University, Taipei, Taiwan.
AD  - Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan.
FAU - Lai, Chun-Fu
AU  - Lai CF
AD  - Department of Internal Medicine, National Taiwan University Hospital, Taipei, 
      Taiwan.
FAU - Ho, Te-Wei
AU  - Ho TW
AD  - Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
AD  - College of Medicine, National Taiwan University, Taipei, Taiwan.
FAU - Lai, Feipei
AU  - Lai F
AD  - Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan 
      University, Taipei, Taiwan.
AD  - Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan.
AD  - Department of Computer Science and Information Engineering, National Taiwan 
      University, Taipei, Taiwan.
LA  - eng
PT  - Journal Article
DEP - 20200708
PL  - Switzerland
TA  - Front Bioeng Biotechnol
JT  - Frontiers in bioengineering and biotechnology
JID - 101632513
PMC - PMC7360801
OTO - NOTNLM
OT  - blood pressure
OT  - diabetes mellitus
OT  - fast Fourier transform
OT  - harmonic
OT  - hemodynamic
OT  - stiffness
EDAT- 2020/08/01 06:00
MHDA- 2020/08/01 06:01
PMCR- 2020/01/01
CRDT- 2020/08/01 06:00
PHST- 2020/02/27 00:00 [received]
PHST- 2020/05/26 00:00 [accepted]
PHST- 2020/08/01 06:00 [entrez]
PHST- 2020/08/01 06:00 [pubmed]
PHST- 2020/08/01 06:01 [medline]
PHST- 2020/01/01 00:00 [pmc-release]
AID - 10.3389/fbioe.2020.00638 [doi]
PST - epublish
SO  - Front Bioeng Biotechnol. 2020 Jul 8;8:638. doi: 10.3389/fbioe.2020.00638. 
      eCollection 2020.