PMID- 32739852
OWN - NLM
STAT- MEDLINE
DCOM- 20201102
LR  - 20201102
IS  - 1532-8171 (Electronic)
IS  - 0735-6757 (Linking)
VI  - 38
IP  - 9
DP  - 2020 Sep
TI  - Predictive factors for acute brain lesions on magnetic resonance imaging in acute 
      carbon monoxide poisoning.
PG  - 1825-1830
LID - S0735-6757(20)30438-1 [pii]
LID - 10.1016/j.ajem.2020.05.076 [doi]
AB  - BACKGROUND: Acute brain lesions on diffusion-weighted-magnetic resonance imaging 
      (MRI) after acute carbon monoxide (CO) poisoning were associated with delayed 
      neurological sequelae. This study was conducted to identify the risk factors 
      associated with acute brain lesions on MRI after acute CO poisoning and to help 
      select patients who need acute-phase brain MRI after acute CO poisoning in the 
      emergency department (ED). METHODS: This retrospective observational study 
      included 103 adult patients who were hospitalized at a tertiary-care hospital 
      between November 2016 and September 2019 and underwent brain MRI because of acute 
      CO poisoning. Multivariable logistic regression analysis was applied to identify 
      predictive factors for acute brain lesions on MRI after acute CO poisoning. 
      RESULTS: Multivariable logistic regression analysis showed that Glasgow Coma 
      Scale (GCS) score of <9 at ED presentation (odds ratio [OR] 17.749, 95% 
      confidence interval [CI] 3.098-101.690, P = 0.001) and the initial troponin-I 
      level at presentation in the ED (OR 13.657, 95% CI 1.415-131.834, P = 0.024) were 
      predictive factors for acute brain lesions on MRI in acute CO poisoning. The 
      receiver operating characteristics curve for initial troponin-I showed an area 
      under the curve of 0.761 (95% CI 0.638-0.883, P < 0.001) and the optimal cutoff 
      value was 0.105 ng/mL. CONCLUSIONS: Acute-phase brain MRI in acute CO poisoning 
      can be considered for patients who present at the ED with a GCS score <9 or 
      troponin-I level >0.105 ng/mL.
CI  - Copyright (c) 2020 Elsevier Inc. All rights reserved.
FAU - Kim, Jang Hyo
AU  - Kim JH
AD  - Department of Emergency Medicine, Inha University, College of Medicine, Incheon, 
      South Korea.
FAU - Durey, Areum
AU  - Durey A
AD  - Department of Emergency Medicine, Inha University, College of Medicine, Incheon, 
      South Korea.
FAU - Han, Seung Baik
AU  - Han SB
AD  - Department of Emergency Medicine, Inha University, College of Medicine, Incheon, 
      South Korea.
FAU - Kim, Ji Hye
AU  - Kim JH
AD  - Department of Emergency Medicine, Inha University, College of Medicine, Incheon, 
      South Korea. Electronic address: ziihye@inha.ac.kr.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20200528
PL  - United States
TA  - Am J Emerg Med
JT  - The American journal of emergency medicine
JID - 8309942
SB  - IM
MH  - Adult
MH  - Carbon Monoxide Poisoning/*complications/*diagnostic imaging
MH  - *Diffusion Magnetic Resonance Imaging
MH  - Emergency Service, Hospital
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neurotoxicity Syndromes/*diagnostic imaging/*etiology
MH  - Retrospective Studies
MH  - Risk Factors
OTO - NOTNLM
OT  - Brain
OT  - Carbon monoxide poisoning
OT  - Magnetic resonance imaging
COIS- Declaration of competing interest None.
EDAT- 2020/08/03 06:00
MHDA- 2020/11/03 06:00
CRDT- 2020/08/03 06:00
PHST- 2020/04/02 00:00 [received]
PHST- 2020/05/22 00:00 [revised]
PHST- 2020/05/22 00:00 [accepted]
PHST- 2020/08/03 06:00 [pubmed]
PHST- 2020/11/03 06:00 [medline]
PHST- 2020/08/03 06:00 [entrez]
AID - S0735-6757(20)30438-1 [pii]
AID - 10.1016/j.ajem.2020.05.076 [doi]
PST - ppublish
SO  - Am J Emerg Med. 2020 Sep;38(9):1825-1830. doi: 10.1016/j.ajem.2020.05.076. Epub 
      2020 May 28.