PMID- 32742368
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1792-0981 (Print)
IS  - 1792-1015 (Electronic)
IS  - 1792-0981 (Linking)
VI  - 20
IP  - 2
DP  - 2020 Aug
TI  - Application of blood pre-albumin and NT-pro BNP levels in evaluating prognosis of 
      elderly chronic heart failure patients.
PG  - 1337-1342
LID - 10.3892/etm.2020.8865 [doi]
AB  - Levels of blood pre-albumin (PA) and N-terminal pro-B-type natriuretic peptide 
      (NT-pro BNP) in elderly patients with chronic heart failure (CHF) and their 
      clinical value in prognosis evaluation were explored. A total of 410 elderly 
      patients aged >/=65 years hospitalized for CHF were enrolled. The concentrations of 
      blood PA and NT-pro BNP, routine blood test and biochemistry indicators were 
      determined and color Doppler echocardiography was performed. Additionally, the 
      patients were followed up after discharge, and based on the occurrence of major 
      adverse cardiac events (MACE), they were divided into MACE group and non-MACE 
      group. MACE group had an older age and a higher level of plasma NT-pro BNP than 
      non-MACE group (77.82+/-6.57) years vs. (76.39+/-6.18) years, and (8,864.52+/-9,718.36) 
      pg/ml vs. (4,165.62+6,437.28) pg/ml (P<0.05), and the left ventricular ejection 
      fraction and serum PA level in MACE group were lower than those in non-MACE group 
      (P<0.05). According to the results of multivariate regression analysis, serum PA 
      [odds ratio (OR)=0.242, 95% confidence interval (CI)=0.137-0.406, P<0.001] and 
      plasma NT-pro BNP (OR=1.847, 95% CI=1.024-3.158, P=0.036) were independent risk 
      factors for the occurrence of cardiac events during follow-up. Decline in PA 
      level and elevation in NT-pro BNP level have a strong correlation with poor 
      prognosis of elderly CHF patients, and they can be used for clinically evaluating 
      disease conditions, guiding treatment and improving prognosis.
CI  - Copyright: (c) Shi et al.
FAU - Shi, Linying
AU  - Shi L
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Beijing 100020, P.R. China.
FAU - Zhang, Yuan
AU  - Zhang Y
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Beijing 100020, P.R. China.
FAU - Zhang, Jing
AU  - Zhang J
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Beijing 100020, P.R. China.
FAU - Gao, Yuanfeng
AU  - Gao Y
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Beijing 100020, P.R. China.
FAU - Liu, Jiamei
AU  - Liu J
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Beijing 100020, P.R. China.
FAU - Chen, Mulei
AU  - Chen M
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Beijing 100020, P.R. China.
FAU - Yang, Xinchun
AU  - Yang X
AD  - Department of Cardiology, Beijing Chaoyang Hospital, Beijing 100020, P.R. China.
LA  - eng
PT  - Journal Article
DEP - 20200610
PL  - Greece
TA  - Exp Ther Med
JT  - Experimental and therapeutic medicine
JID - 101531947
PMC - PMC7388205
OTO - NOTNLM
OT  - N-terminal pro-B-type natriuretic peptide
OT  - chronic heart failure
OT  - major adverse cardiac events
OT  - pre-albumin
OT  - prognosis
OT  - the elderly
EDAT- 2020/08/04 06:00
MHDA- 2020/08/04 06:01
PMCR- 2020/06/10
CRDT- 2020/08/04 06:00
PHST- 2019/11/05 00:00 [received]
PHST- 2020/03/03 00:00 [accepted]
PHST- 2020/08/04 06:00 [entrez]
PHST- 2020/08/04 06:00 [pubmed]
PHST- 2020/08/04 06:01 [medline]
PHST- 2020/06/10 00:00 [pmc-release]
AID - ETM-0-0-8865 [pii]
AID - 10.3892/etm.2020.8865 [doi]
PST - ppublish
SO  - Exp Ther Med. 2020 Aug;20(2):1337-1342. doi: 10.3892/etm.2020.8865. Epub 2020 Jun 
      10.