PMID- 32746355 OWN - NLM STAT- MEDLINE DCOM- 20210514 LR - 20210514 IS - 1940-9990 (Electronic) IS - 1932-4545 (Linking) VI - 14 IP - 4 DP - 2020 Aug TI - Bladder Volume Monitoring Using Electrical Impedance Tomography With Simultaneous Multi-Tone Tissue Stimulation and DFT-Based Impedance Calculation Inside an FPGA. PG - 775-786 LID - 10.1109/TBCAS.2020.3008831 [doi] AB - In this article, a novel method for measuring the volume of the urinary bladder non-invasively is presented that relies on the principles dictated by Electrical Impedance Tomography (EIT). The electronic prototype responsible for injecting innocuous electrical currents to the lower abdominal region and measuring the developed voltage levels is fully described, as well as the computational models for resolution of the so-called Forward and Inverse Problems in Imaging. The simultaneous multi-tone injection of current provided by a high performance Field Programmable Gate Array (FPGA), combined with impedance estimation by the Discrete Fourier Transform (DFT) constitutes a novelty in Urodynamics with potential to monitor continuously the intravesical volume of patients in a much faster and comfortable way than traditional transurethral catheterization methods. The resolution of the Inverse Problem is performed by the Gauss-Newton method with Laplacian regularization, allowing to obtain a sectional representation of the volume of urine encompassed by the bladder and surrounding body tissues. Experimentation has been carried out with synthetic phantoms and human subjects with results showing a good correlation between the levels of abdominal admittivity acquired by the EIT system and the volume of ingested water. FAU - Rosa, Bruno M G AU - Rosa BMG FAU - Yang, Guang Z AU - Yang GZ LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20200713 PL - United States TA - IEEE Trans Biomed Circuits Syst JT - IEEE transactions on biomedical circuits and systems JID - 101312520 SB - IM MH - Adult MH - *Electric Impedance MH - Electrodes MH - Equipment Design MH - *Fourier Analysis MH - Humans MH - Male MH - Phantoms, Imaging MH - Signal Processing, Computer-Assisted/instrumentation MH - Tomography/*instrumentation MH - *Urinary Bladder/anatomy & histology/diagnostic imaging/physiology EDAT- 2020/08/04 06:00 MHDA- 2021/05/15 06:00 CRDT- 2020/08/04 06:00 PHST- 2020/08/04 06:00 [pubmed] PHST- 2021/05/15 06:00 [medline] PHST- 2020/08/04 06:00 [entrez] AID - 10.1109/TBCAS.2020.3008831 [doi] PST - ppublish SO - IEEE Trans Biomed Circuits Syst. 2020 Aug;14(4):775-786. doi: 10.1109/TBCAS.2020.3008831. Epub 2020 Jul 13.