PMID- 32748157
OWN - NLM
STAT- MEDLINE
DCOM- 20210818
LR  - 20210818
IS  - 1572-8595 (Electronic)
IS  - 1383-875X (Linking)
VI  - 59
IP  - 2
DP  - 2020 Nov
TI  - His bundle pacing for cardiac resynchronization therapy: a systematic literature 
      review and meta-analysis.
PG  - 463-470
LID - 10.1007/s10840-020-00827-6 [doi]
AB  - BACKGROUND: Permanent His bundle pacing has been to shown to be an alternative 
      for the patients with CRT indications and more recently has been evaluated for 
      feasibility as a first-line strategy. Data on His bundle pacing (HBP) for cardiac 
      resynchronization therapy are largely limited to small single-center reports, and 
      clinical benefits and risks have not been systematically examined. The purpose of 
      this study was to systematically review published studies of HBP for cardiac 
      resynchronization therapy and evaluate the feasibility and efficacy of the 
      therapy. METHODS: PubMed, Cochrane Library, Embase, CNKI, and WANFANG databases 
      were searched up to December 2019 to identify relevant studies. Clinical outcomes 
      of interest include implant success rate; Q wave, R wave, and S wave QRS 
      duration; pacing thresholds; left ventricular ejection fraction (LVEF); left 
      ventricular end-diastolic dimension (LVEDD); and New York Heart Association 
      (NYHA) status, complications, and mortality. Extract and summarize the data. 
      Using Revman5.3 software to perform the meta-analysis. RESULTS: A total of 13 
      studies involving 503 patients were included. The average implant success rate 
      was 79.8% (95% CI 72.4-87.2%). Permanent HBP resulted in a significant narrow of 
      mean QRS duration from 165.5 +/- 8.7 to 122.9 +/- 12.0 ms (MD = 43.5, 95%Cl: 
      36.34 ~ 50.56, p < 0.001). A trend of increase was observed in capture thresholds 
      at follow-up compared with that in the baseline threshold (MD = - 0.24, 95% Cl: 
      - 0.38 ~ - 0.10, p = 0.001). Average NYHA functional class (MD = 1.2, 95% CI: 
      1.09 ~ 1.31, p < 0.001), LVEF (MD = - 12.60, 95% Cl: - 14.32 ~ - 10.87, 
      p < 0.001), LVEDD (MD = 4.30, 95% Cl: 3.05 ~ 5.55, p < 0.001) significantly 
      improved at > 3 months follow-up compared with that of the baseline (p < 0.001). 
      Ten studies reported safety information and the most commonly reported 
      complication was the increase in HB capture threshold. CONCLUSIONS: HBP is 
      feasible with a reasonable success rate in patients requiring CRT. HBP could 
      achieve significant narrow of QRS duration and improve left ventricular function 
      during follow-up. Randomized controlled trials are needed to further assess the 
      efficacy of HBP compared with that of biventricular pacing (BVP) in achieving 
      CRT. Graphical abstract Schematic representation of detecting ofloxacin (OFL) by 
      differential pulse voltammetry approach based on the laser modified glassy carbon 
      electrode (LGCE), which increased the active functional groups and surface area 
      compared to GCE.
FAU - Qi, Jinlei
AU  - Qi J
AD  - Department of Cardiology, Affiliated Hospital of Heibei University, Yu Hua 
      Street, Baoding, China. qijinlei93@qq.com.
FAU - Jia, Xinwei
AU  - Jia X
AD  - Department of Cardiology, Affiliated Hospital of Heibei University, Yu Hua 
      Street, Baoding, China.
FAU - Wang, Zhanqi
AU  - Wang Z
AD  - Department of Cardiology, Affiliated Hospital of Heibei University, Yu Hua 
      Street, Baoding, China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20200803
PL  - Netherlands
TA  - J Interv Card Electrophysiol
JT  - Journal of interventional cardiac electrophysiology : an international journal of 
      arrhythmias and pacing
JID - 9708966
SB  - IM
MH  - Bundle of His
MH  - Cardiac Pacing, Artificial
MH  - *Cardiac Resynchronization Therapy
MH  - Humans
MH  - Stroke Volume
MH  - Treatment Outcome
MH  - Ventricular Function, Left
OTO - NOTNLM
OT  - Cardiac resynchronization therapy
OT  - His bundle pacing
OT  - Meta-analysis
OT  - Systematic review
EDAT- 2020/08/05 06:00
MHDA- 2021/08/19 06:00
CRDT- 2020/08/05 06:00
PHST- 2020/06/22 00:00 [received]
PHST- 2020/07/17 00:00 [accepted]
PHST- 2020/08/05 06:00 [pubmed]
PHST- 2021/08/19 06:00 [medline]
PHST- 2020/08/05 06:00 [entrez]
AID - 10.1007/s10840-020-00827-6 [pii]
AID - 10.1007/s10840-020-00827-6 [doi]
PST - ppublish
SO  - J Interv Card Electrophysiol. 2020 Nov;59(2):463-470. doi: 
      10.1007/s10840-020-00827-6. Epub 2020 Aug 3.