PMID- 32748234 OWN - NLM STAT- MEDLINE DCOM- 20210924 LR - 20210924 IS - 1433-7347 (Electronic) IS - 0942-2056 (Linking) VI - 29 IP - 10 DP - 2021 Oct TI - Improvements in functional outcome and quality of life are not sustainable for patients >/= 68 years old 10 years after total knee arthroplasty. PG - 3330-3336 LID - 10.1007/s00167-020-06200-4 [doi] AB - PURPOSE: The aims of this study are to evaluate whether improvements in functional outcome and quality of life are sustainable 10 years after total knee arthroplasty (TKA), and the age cut-off for clinical deterioration in outcomes METHODS: Prospectively collected registry data of 120 consecutive patients who underwent TKA at a tertiary hospital in 2006 was analysed. All patients were assessed at 6 months, 2 years and 10 years using the Knee Society Function Score, Knee Society Knee Score, Oxford Knee Score, Short-Form 36 Physical/Mental Component Scores and postoperative satisfaction. One-way ANOVA was used to compare continuous variables, while Chi-squared test to compare categorical variables. Multivariate logistic regression and receiver operating curve analysis was performed to evaluate the predictive factors associated with deterioration of scores postoperatively. RESULTS: Significant improvements were noted in all functional outcome and quality of life scores at 6 months after TKA. Between 6 months and 2 years, the KSFS and OKS continued to improve but the KSKS, PCS and MCS plateaued. Between 2 and 10 years, there was a deterioration in the KSFS and OKS, whilst KSKS, PCS and MCS were maintained. Increasing age was noted to be a significant risk factor for deterioration of KSFS at 10 years with age >/= 68 as the cut-off value. 91.7% of patients with KSFS Minimally Clinically Important Difference(MCID) (>/= 7 points) continued to be satisfied after 10 years compared to 100.0% who did not experience KSFS MCID deterioration (p = 0.02). CONCLUSION: Patients >/= 68 years experience deterioration in functional outcomes and quality of life from 2 to 10 years after TKA. LEVEL OF EVIDENCE: Retrospective study, Level III. CI - (c) 2020. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA). FAU - Woo, Bo Jun AU - Woo BJ AUID- ORCID: 0000-0001-9641-3018 AD - Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road Academia Building Level 4, Singapore, 169608, Singapore. bojun.woo@mohh.com.sg. FAU - Chen, Jerry Yongqiang AU - Chen JY AD - Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road Academia Building Level 4, Singapore, 169608, Singapore. FAU - Lai, Yu Ming AU - Lai YM AD - Department of General Surgery, Singapore General Hospital, Singapore, Singapore. FAU - Liow, Ming Han Lincoln AU - Liow MHL AD - Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road Academia Building Level 4, Singapore, 169608, Singapore. FAU - Lo, Ngai Nung AU - Lo NN AD - Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road Academia Building Level 4, Singapore, 169608, Singapore. FAU - Yeo, Seng Jin AU - Yeo SJ AD - Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road Academia Building Level 4, Singapore, 169608, Singapore. LA - eng PT - Journal Article DEP - 20200803 PL - Germany TA - Knee Surg Sports Traumatol Arthrosc JT - Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA JID - 9314730 SB - IM MH - Aged MH - *Arthroplasty, Replacement, Knee MH - Child MH - Humans MH - *Osteoarthritis, Knee/surgery MH - Quality of Life MH - Retrospective Studies MH - Treatment Outcome OTO - NOTNLM OT - Quality of life OT - Total knee arthroplasty OT - Total knee replacement EDAT- 2020/08/05 06:00 MHDA- 2021/09/25 06:00 CRDT- 2020/08/05 06:00 PHST- 2020/06/14 00:00 [received] PHST- 2020/07/29 00:00 [accepted] PHST- 2020/08/05 06:00 [pubmed] PHST- 2021/09/25 06:00 [medline] PHST- 2020/08/05 06:00 [entrez] AID - 10.1007/s00167-020-06200-4 [pii] AID - 10.1007/s00167-020-06200-4 [doi] PST - ppublish SO - Knee Surg Sports Traumatol Arthrosc. 2021 Oct;29(10):3330-3336. doi: 10.1007/s00167-020-06200-4. Epub 2020 Aug 3.