PMID- 32755825
OWN - NLM
STAT- MEDLINE
DCOM- 20210709
LR  - 20210709
IS  - 1878-0334 (Electronic)
IS  - 1871-4021 (Linking)
VI  - 14
IP  - 5
DP  - 2020 Sep-Oct
TI  - Prevalence of hypogonadism in patients with type 2 diabetes mellitus among the 
      Indian population.
PG  - 1299-1304
LID - S1871-4021(20)30252-6 [pii]
LID - 10.1016/j.dsx.2020.07.006 [doi]
AB  - OBJECTIVES: To determine the prevalence of hypogonadism among Indian men with and 
      without type 2 diabetes mellitus (T2DM) and evaluate its association with various 
      metabolic parameters. METHODS: One hundred fifty consecutive men with T2DM, aged 
      25-70 years, and one hundred age-matched healthy men without diabetes were 
      included. The free testosterone (FT) level was calculated using the total 
      testosterone (TT), sex hormone-binding globulin (SHBG), and albumin levels in 
      serum. Patients with a calculated FT level <6.35 ng/dL and a positive response on 
      the androgen deficiency in aging male questionnaire (ADAM) were diagnosed with 
      hypogonadism. RESULTS: The prevalence of hypogonadism was 17.3% and 10% in men 
      with and without T2DM, respectively. The body mass index (BMI) and the mean 
      levels of follicle-stimulating hormone (FSH), TT, SHBG, Triglycerides (TG), and 
      FT were significantly different between the groups. The mean BMI and TG levels 
      were significantly higher in patients with T2DM than in those without. Both 
      groups showed a significant negative correlation between the BMI and SHBG level. 
      CONCLUSION: The hypogonadism prevalence was higher in patients with T2DM than in 
      those without, although the difference did not reach statistical significance.
CI  - Copyright (c) 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved.
FAU - Anupam, Biswas
AU  - Anupam B
FAU - Shivaprasad, Channabasappa
AU  - Shivaprasad C
FAU - Vijaya, Sarathi
AU  - Vijaya S
FAU - Sridevi, Atluri
AU  - Sridevi A
FAU - Aiswarya, Yalamanchi
AU  - Aiswarya Y
FAU - Nikhil, Kumar
AU  - Nikhil K
LA  - eng
PT  - Journal Article
DEP - 20200718
PL  - Netherlands
TA  - Diabetes Metab Syndr
JT  - Diabetes & metabolic syndrome
JID - 101462250
RN  - 3XMK78S47O (Testosterone)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*complications
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Hypogonadism/blood/*epidemiology/etiology/pathology
MH  - India/epidemiology
MH  - Middle Aged
MH  - Prevalence
MH  - Prognosis
MH  - Prospective Studies
MH  - Surveys and Questionnaires
MH  - Testosterone/blood
OTO - NOTNLM
OT  - Diabetes mellitus
OT  - Hypogonadism
OT  - Prevalence
OT  - Type 2
COIS- Declaration of competing interest None.
EDAT- 2020/08/07 06:00
MHDA- 2021/07/10 06:00
CRDT- 2020/08/07 06:00
PHST- 2020/06/08 00:00 [received]
PHST- 2020/06/28 00:00 [revised]
PHST- 2020/07/03 00:00 [accepted]
PHST- 2020/08/07 06:00 [pubmed]
PHST- 2021/07/10 06:00 [medline]
PHST- 2020/08/07 06:00 [entrez]
AID - S1871-4021(20)30252-6 [pii]
AID - 10.1016/j.dsx.2020.07.006 [doi]
PST - ppublish
SO  - Diabetes Metab Syndr. 2020 Sep-Oct;14(5):1299-1304. doi: 
      10.1016/j.dsx.2020.07.006. Epub 2020 Jul 18.