PMID- 32759722
OWN - NLM
STAT- MEDLINE
DCOM- 20210318
LR  - 20210318
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 12
IP  - 8
DP  - 2020 Aug 4
TI  - Relationship between Nutritional Status and Clinical and Biochemical Parameters 
      in Hospitalized Patients with Heart Failure with Reduced Ejection Fraction, with 
      1-year Follow-Up.
LID - 10.3390/nu12082330 [doi]
LID - 2330
AB  - Heart Failure (HF) is a cardiovascular disease with continually increasing 
      morbidity and high mortality. The purpose of this study was to analyze 
      nutritional status in patients diagnosed with HF with reduced ejection fraction 
      (HFrEF) and evaluate the impact of malnutrition on their prognosis. The Polish 
      version of MNA form (Mini Nutritional Assessment) was used to assess the 
      patients' nutritional status. The New York Heart Association (NYHA) class, 
      exacerbation of HF, chosen echocardiographic and biochemical parameters, e.g., 
      natriuretic peptides or serum albumin, were also analyzed. Among the 120 
      consecutive patients, 47 (39%) had a normal nutritional status, 62 (52%) were at 
      risk of malnutrition and 11 (9%) were malnourished. The patients with 
      malnutrition more frequently presented with HF exacerbation in comparison to 
      those with normal nutritional status (82% vs. 30% respectively, p = 0.004). There 
      were no significant differences between the investigated groups as to natriuretic 
      peptides; however, both the malnourished patients and those at risk of 
      malnutrition tend to show higher B-type natriuretic peptide (BNP) and NT-proBNP 
      concentrations. During the average 344 days of follow-up 19 patients died and 25 
      were hospitalized due to decompensated HF. Malnutrition or being at risk of 
      malnutrition seems to be associated with both worse outcomes and clinical status 
      in HFrEF patients.
FAU - Kaluzna-Oleksy, Marta
AU  - Kaluzna-Oleksy M
AD  - 1st Department of Cardiology, University of Medical Sciences in Poznan, 61-848 
      Poznan, Poland.
AD  - Poznan University of Medical Sciences Hospital of Lord's Transfiguration, 61-848 
      Poznan, Poland.
FAU - Krysztofiak, Helena
AU  - Krysztofiak H
AD  - 1st Department of Cardiology, University of Medical Sciences in Poznan, 61-848 
      Poznan, Poland.
FAU - Migaj, Jacek
AU  - Migaj J
AD  - 1st Department of Cardiology, University of Medical Sciences in Poznan, 61-848 
      Poznan, Poland.
AD  - Poznan University of Medical Sciences Hospital of Lord's Transfiguration, 61-848 
      Poznan, Poland.
FAU - Wleklik, Marta
AU  - Wleklik M
AUID- ORCID: 0000-0001-9574-4448
AD  - Faculty of Health Sciences, Wroclaw Medical University, 50-367 Wroclaw, Poland.
FAU - Dudek, Magdalena
AU  - Dudek M
AD  - 1st Department of Cardiology, University of Medical Sciences in Poznan, 61-848 
      Poznan, Poland.
AD  - Poznan University of Medical Sciences Hospital of Lord's Transfiguration, 61-848 
      Poznan, Poland.
FAU - Uchmanowicz, Izabella
AU  - Uchmanowicz I
AUID- ORCID: 0000-0001-5452-0210
AD  - Faculty of Health Sciences, Wroclaw Medical University, 50-367 Wroclaw, Poland.
FAU - Lesiak, Maciej
AU  - Lesiak M
AUID- ORCID: 0000-0003-2630-5016
AD  - 1st Department of Cardiology, University of Medical Sciences in Poznan, 61-848 
      Poznan, Poland.
AD  - Poznan University of Medical Sciences Hospital of Lord's Transfiguration, 61-848 
      Poznan, Poland.
FAU - Straburzynska-Migaj, Ewa
AU  - Straburzynska-Migaj E
AD  - 1st Department of Cardiology, University of Medical Sciences in Poznan, 61-848 
      Poznan, Poland.
AD  - Poznan University of Medical Sciences Hospital of Lord's Transfiguration, 61-848 
      Poznan, Poland.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20200804
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
RN  - 0 (Biomarkers)
RN  - 0 (Peptide Fragments)
RN  - 0 (Serum Albumin)
RN  - 0 (pro-brain natriuretic peptide (1-76))
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
MH  - Aged
MH  - Biomarkers/blood
MH  - Blood Pressure
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Disease Risk Factors
MH  - Heart Failure/complications/*mortality/physiopathology
MH  - Hospitalization/statistics & numerical data
MH  - Humans
MH  - Male
MH  - Malnutrition/etiology/*mortality/physiopathology
MH  - Middle Aged
MH  - Natriuretic Peptide, Brain/blood
MH  - Nutrition Assessment
MH  - *Nutritional Status
MH  - Peptide Fragments/blood
MH  - Prognosis
MH  - Prospective Studies
MH  - Serum Albumin/analysis
MH  - *Stroke Volume
PMC - PMC7468814
OTO - NOTNLM
OT  - heart failure
OT  - malnutrition
OT  - mortality
OT  - nutritional status
OT  - reduced ejection fraction
COIS- The authors declare no conflict of interest.
EDAT- 2020/08/08 06:00
MHDA- 2021/03/19 06:00
PMCR- 2020/08/01
CRDT- 2020/08/08 06:00
PHST- 2020/07/09 00:00 [received]
PHST- 2020/07/31 00:00 [revised]
PHST- 2020/08/02 00:00 [accepted]
PHST- 2020/08/08 06:00 [entrez]
PHST- 2020/08/08 06:00 [pubmed]
PHST- 2021/03/19 06:00 [medline]
PHST- 2020/08/01 00:00 [pmc-release]
AID - nu12082330 [pii]
AID - nutrients-12-02330 [pii]
AID - 10.3390/nu12082330 [doi]
PST - epublish
SO  - Nutrients. 2020 Aug 4;12(8):2330. doi: 10.3390/nu12082330.