PMID- 3276380
OWN - NLM
STAT- MEDLINE
DCOM- 19880302
LR  - 20190619
IS  - 0008-543X (Print)
IS  - 0008-543X (Linking)
VI  - 61
IP  - 3
DP  - 1988 Feb 1
TI  - Congenital self-healing histiocytosis (Hashimoto-Pritzker). An ultrastructural 
      and immunohistochemical study.
PG  - 508-16
AB  - Congenital self-healing histiocytosis (CSHH) is a rare primary histiocytic skin 
      disorder. Only a few cases have been studied by ultrastructure and 
      immunohistochemistry. Here we report a new case that was investigated using an 
      electron microscope and a panel of monoclonal (MCA) and polyclonal (PCA) 
      antibodies. CSHH cells were found to bear the immunohistochemical phenotype of 
      normal epidermal Langerhans cells (LC) and histiocytosis X (HX) cells (CD1a/c+, 
      CD1b-, CD4+/-, human leukocyte antigen [HLA]-DR/DQ+, S-100+). However, an 
      electron microscope showed a paucity of Birbeck granule (BG)-containing cells. 
      This contrasted with their immunophenotype. This finding, along with other 
      ultrastructural characteristics of CSHH cells, suggests that histologic 
      differences exist between CSHH and HX. However, because no absolute histologic 
      criterion is known that allows unequivocally the differential diagnosis between 
      the two diseases, this distinction currently has to rely on clinical criteria, 
      mainly the regressive course observed within a few months in CSHH. The precise 
      nosologic position of CSHH among other histiocytic syndromes remains unsettled.
FAU - Kanitakis, J
AU  - Kanitakis J
AD  - INSERM U209, Clinique Dermatologique, Hop. Ed. Herriot, Lyon, France.
FAU - Zambruno, G
AU  - Zambruno G
FAU - Schmitt, D
AU  - Schmitt D
FAU - Cambazard, F
AU  - Cambazard F
FAU - Jacquemier, D
AU  - Jacquemier D
FAU - Thivolet, J
AU  - Thivolet J
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Cancer
JT  - Cancer
JID - 0374236
RN  - 0 (Antibodies, Monoclonal)
SB  - IM
MH  - Antibodies, Monoclonal/immunology
MH  - Cell Division
MH  - Female
MH  - Humans
MH  - Immunohistochemistry
MH  - Infant, Newborn
MH  - Lymphatic Diseases/congenital/*immunology/pathology
MH  - Phenotype
MH  - Skin Neoplasms/complications/*immunology/pathology
RF  - 60
EDAT- 1988/02/01 00:00
MHDA- 1988/02/01 00:01
CRDT- 1988/02/01 00:00
PHST- 1988/02/01 00:00 [pubmed]
PHST- 1988/02/01 00:01 [medline]
PHST- 1988/02/01 00:00 [entrez]
AID - 10.1002/1097-0142(19880201)61:3<508::aid-cncr2820610316>3.0.co;2-2 [doi]
PST - ppublish
SO  - Cancer. 1988 Feb 1;61(3):508-16. doi: 
      10.1002/1097-0142(19880201)61:3<508::aid-cncr2820610316>3.0.co;2-2.