PMID- 32764621
OWN - NLM
STAT- MEDLINE
DCOM- 20201215
LR  - 20210806
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 10
IP  - 1
DP  - 2020 Aug 6
TI  - The vomeronasal system of the newborn capybara: a morphological and 
      immunohistochemical study.
PG  - 13304
LID - 10.1038/s41598-020-69994-w [doi]
LID - 13304
AB  - The vomeronasal system (VNS) is responsible for the perception mainly of 
      pheromones and kairomones. Primarily studied in laboratory rodents, it plays a 
      crucial role in their socio-sexual behaviour. As a wild rodent, the capybara 
      offers a more objective and representative perspective to understand the 
      significance of the system in the Rodentia, avoiding the risk of extrapolating 
      from laboratory rodent strains, exposed to high levels of artificial selection 
      pressure. We have studied the main morphological and immunohistochemical features 
      of the capybara vomeronasal organ (VNO) and accessory olfactory bulb (AOB). The 
      study was done in newborn individuals to investigate the maturity of the system 
      at this early stage. We used techniques such as histological stains, 
      lectins-labelling and immunohistochemical characterization of a range of 
      proteins, including G proteins (Galphai2, Galphao) and olfactory marking protein. As a 
      result, we conclude that the VNS of the capybara at birth is capable of 
      establishing the same function as that of the adult, and that it presents unique 
      features as the high degree of differentiation of the AOB and the active cellular 
      migration in the vomeronasal epithelium. All together makes the capybara a 
      promising model for the study of chemical communication in the first days of 
      life.
FAU - Torres, Mateo V
AU  - Torres MV
AUID- ORCID: 0000-0002-7671-3379
AD  - Department of Anatomy, Animal Production, and Clinical Veterinary Sciences. 
      Faculty of Veterinary, University of Santiago de Compostela, Av Carballo Calero 
      s/n, 27002, Lugo, Spain.
FAU - Ortiz-Leal, Irene
AU  - Ortiz-Leal I
AUID- ORCID: 0000-0002-8468-3659
AD  - Department of Anatomy, Animal Production, and Clinical Veterinary Sciences. 
      Faculty of Veterinary, University of Santiago de Compostela, Av Carballo Calero 
      s/n, 27002, Lugo, Spain.
FAU - Villamayor, Paula R
AU  - Villamayor PR
AUID- ORCID: 0000-0002-7361-7795
AD  - Department of Anatomy, Animal Production, and Clinical Veterinary Sciences. 
      Faculty of Veterinary, University of Santiago de Compostela, Av Carballo Calero 
      s/n, 27002, Lugo, Spain.
FAU - Ferreiro, Andrea
AU  - Ferreiro A
AD  - Marcelle Nature Park, Outeiro de Rei, Lugo, Spain.
FAU - Rois, Jose Luis
AU  - Rois JL
AD  - Marcelle Nature Park, Outeiro de Rei, Lugo, Spain.
FAU - Sanchez-Quinteiro, Pablo
AU  - Sanchez-Quinteiro P
AUID- ORCID: 0000-0002-9891-4817
AD  - Department of Anatomy, Animal Production, and Clinical Veterinary Sciences. 
      Faculty of Veterinary, University of Santiago de Compostela, Av Carballo Calero 
      s/n, 27002, Lugo, Spain. pablo.sanchez@usc.es.
LA  - eng
PT  - Journal Article
DEP - 20200806
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
RN  - 0 (Lectins)
SB  - IM
MH  - Animals
MH  - Animals, Newborn
MH  - Immunohistochemistry
MH  - Lectins/metabolism
MH  - Rodentia/*anatomy & histology
MH  - Vomeronasal Organ/*anatomy & histology/*metabolism
PMC - PMC7411026
COIS- The authors declare no competing interests.
EDAT- 2020/08/09 06:00
MHDA- 2020/12/16 06:00
PMCR- 2020/08/06
CRDT- 2020/08/09 06:00
PHST- 2020/04/11 00:00 [received]
PHST- 2020/07/22 00:00 [accepted]
PHST- 2020/08/09 06:00 [entrez]
PHST- 2020/08/09 06:00 [pubmed]
PHST- 2020/12/16 06:00 [medline]
PHST- 2020/08/06 00:00 [pmc-release]
AID - 10.1038/s41598-020-69994-w [pii]
AID - 69994 [pii]
AID - 10.1038/s41598-020-69994-w [doi]
PST - epublish
SO  - Sci Rep. 2020 Aug 6;10(1):13304. doi: 10.1038/s41598-020-69994-w.