PMID- 32772997
OWN - NLM
STAT- MEDLINE
DCOM- 20210621
LR  - 20210621
IS  - 1467-1107 (Electronic)
IS  - 1047-9511 (Linking)
VI  - 30
IP  - 10
DP  - 2020 Oct
TI  - Catheter-based palliation for infants with tetralogy of Fallot.
PG  - 1469-1472
LID - 10.1017/S1047951120002334 [doi]
AB  - BACKGROUND: The optimal management of symptomatic tetralogy of Fallot in neonates 
      and younger infants with unfavourable anatomy is unclear and is further 
      constrained by resource limitations in low and middle income countries. METHODS: 
      Retrospective medical record review of infants with tetralogy of Fallot 
      undergoing corrective or palliative procedures between January 2016 and June 
      2019. RESULTS: The study included 120 infants; of whom 83 underwent primary 
      complete repair, four underwent surgical palliation, and 33 underwent 
      catheter-based palliation, including balloon pulmonary valvuloplasty (n = 18), 
      right ventricular outflow tract stenting (n = 14), and stenting of the patent 
      arterial duct (n = 1). Infants undergoing catheter-based procedures were younger 
      in age (median 32 days; inter-quartile range (IQR) 7-144 versus 210 days; IQR 
      158-250), with lower baseline saturation (65 +/- 12% versus 87 +/- 7%) and had 
      smaller pulmonary artery z-scores compared to the complete repair cohort. 
      Follow-up was available for 31/33 (94%) infants (median 7 months [IQR 4-11]) who 
      underwent trans-catheter palliation; 12 underwent complete repair, 10 are well, 
      awaiting repair, eight required further palliation (catheter: 6; surgical: 2), 
      and one died post-discharge from non-cardiac causes. CONCLUSION: Catheter-based 
      palliation is a safe and effective alternative in infants with tetralogy of 
      Fallot who are at high risk for primary surgical repair.
FAU - Lingaswamy, Dasana
AU  - Lingaswamy D
AD  - Department of Paediatric Cardiology, Amrita Institute of Medical Sciences, Kochi, 
      India.
FAU - Koepcke, Louisa
AU  - Koepcke L
AD  - Paracelsus Medical School, Nuremberg, Germany.
FAU - Krishna, Mani Ram
AU  - Krishna MR
AUID- ORCID: 0000-0003-1178-4288
AD  - Department of Paediatric Cardiology, Amrita Institute of Medical Sciences, Kochi, 
      India.
FAU - Kottayil, Brijesh P
AU  - Kottayil BP
AD  - Department of Cardio-vascular and Thoracic Surgery, Amrita Institute of Medical 
      Sciences, Kochi, India.
FAU - Sunil, Gopalraj S
AU  - Sunil GS
AD  - Department of Cardio-vascular and Thoracic Surgery, Amrita Institute of Medical 
      Sciences, Kochi, India.
FAU - Moynihan, Katie
AU  - Moynihan K
AD  - Department of Cardiology, Boston Children's Hospital, Boston, MA, USA.
AD  - Department of Paediatrics, Harvard Medical School,Boston, MA, USA.
FAU - Seshadri, Balaji
AU  - Seshadri B
AD  - Department of Paediatrics (Cardiology), Oregon Health and Sciences University, 
      Portland, OR, USA.
FAU - Kumar, Raman Krishna
AU  - Kumar RK
AUID- ORCID: 0000-0003-4343-0951
AD  - Department of Paediatric Cardiology, Amrita Institute of Medical Sciences, Kochi, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20200810
PL  - England
TA  - Cardiol Young
JT  - Cardiology in the young
JID - 9200019
SB  - IM
MH  - Aftercare
MH  - Catheters
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Patient Discharge
MH  - Retrospective Studies
MH  - *Tetralogy of Fallot/surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Trans-catheter palliation
OT  - intra-cardiac repair
OT  - tetralogy of Fallot treatment
EDAT- 2020/08/11 06:00
MHDA- 2021/06/22 06:00
CRDT- 2020/08/11 06:00
PHST- 2020/08/11 06:00 [pubmed]
PHST- 2021/06/22 06:00 [medline]
PHST- 2020/08/11 06:00 [entrez]
AID - S1047951120002334 [pii]
AID - 10.1017/S1047951120002334 [doi]
PST - ppublish
SO  - Cardiol Young. 2020 Oct;30(10):1469-1472. doi: 10.1017/S1047951120002334. Epub 
      2020 Aug 10.