PMID- 32773271
OWN - NLM
STAT- MEDLINE
DCOM- 20210428
LR  - 20210428
IS  - 1532-8406 (Electronic)
IS  - 0883-5403 (Linking)
VI  - 36
IP  - 1
DP  - 2021 Jan
TI  - Class III Obesity Increases Risk of Failure to Achieve the 1-Year Hip Disability 
      and Osteoarthritis Outcome Score-Physical Function Short Form Minimal Clinically 
      Important Difference Following Total Hip Arthroplasty.
PG  - 187-192
LID - S0883-5403(20)30793-2 [pii]
LID - 10.1016/j.arth.2020.07.035 [doi]
AB  - BACKGROUND: The relationship between obesity and failure to achieve a minimal 
      clinically important difference (MCID) following total hip arthroplasty (THA) has 
      not been well defined. The aims of this study are to determine whether increasing 
      body mass index (BMI) is associated with failure to achieve the 1-year Hip 
      Disability and Osteoarthritis Outcome Score-Physical Function Short Form 
      (HOOS-PS) MCID and to determine a threshold BMI beyond which this risk is 
      significantly increased. METHODS: A multi-institutional arthroplasty registry was 
      queried for THA patients from 2016 to 2018 with completion of preoperative and 
      1-year postoperative HOOS-PS. A previously defined anchor-based MCID threshold of 
      23 was used. Variables collected included demographics and patient-reported 
      outcome measures. BMI was analyzed continuously and categorically. The 
      association was analyzed via logistic regression. A BMI threshold was determined 
      using the Youden index and receiver operating characteristic curve. RESULTS: A 
      total of 1256 THAs were included. The average HOOS-PS improvement was 27.6 +/- 18 
      points. The area under the receiver operating characteristic curve for BMI and 
      risk of failure to achieve HOOS-PS MCID was 0.54 (95% confidence interval [CI], 
      0.50-0.57). Increasing BMI assessed continuously was a significant risk factor 
      (odds ratio [OR], 1.03; 95% CI, 1.01-1.05; P value = .010). When BMI was analyzed 
      categorically, this association was only observed for obese class III patients 
      (>40 kg/m(2)) (OR, 2.5; 95% CI, 1.21-5.3; P value = .010). CONCLUSION: This study 
      found an association between increasing BMI and failure to achieve the 1-year 
      HOOS-PS MCID. Obese class III patients (>40 kg/m(2)) face a near 3-fold increased 
      risk of suffering this adverse outcome.
CI  - Copyright (c) 2020. Published by Elsevier Inc.
FAU - Katakam, Akhil
AU  - Katakam A
AD  - Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard 
      Medical School, Boston, MA; Department of Orthopaedic Surgery, Newton-Wellesley 
      Hospital, Newton, MA.
FAU - Florissi, Isabella S
AU  - Florissi IS
AD  - Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard 
      Medical School, Boston, MA.
FAU - Colon Iban, Yhan E
AU  - Colon Iban YE
AD  - Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard 
      Medical School, Boston, MA.
FAU - Bragdon, Charles R
AU  - Bragdon CR
AD  - Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard 
      Medical School, Boston, MA.
FAU - Chen, Antonia F
AU  - Chen AF
AD  - Department of Orthopaedic Surgery, Brigham and Women's Hospital, Harvard Medical 
      School, Boston, MA.
FAU - Melnic, Christopher M
AU  - Melnic CM
AD  - Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard 
      Medical School, Boston, MA; Department of Orthopaedic Surgery, Newton-Wellesley 
      Hospital, Newton, MA.
FAU - Bedair, Hany S
AU  - Bedair HS
AD  - Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard 
      Medical School, Boston, MA; Department of Orthopaedic Surgery, Newton-Wellesley 
      Hospital, Newton, MA.
LA  - eng
PT  - Journal Article
DEP - 20200721
PL  - United States
TA  - J Arthroplasty
JT  - The Journal of arthroplasty
JID - 8703515
SB  - IM
MH  - *Arthroplasty, Replacement, Hip/adverse effects
MH  - Humans
MH  - Minimal Clinically Important Difference
MH  - Obesity/complications/epidemiology
MH  - *Osteoarthritis
MH  - *Osteoarthritis, Hip/surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - HOOS
OT  - MCID
OT  - PROM
OT  - THA
OT  - morbid obesity
OT  - obesity
EDAT- 2020/08/11 06:00
MHDA- 2021/04/29 06:00
CRDT- 2020/08/11 06:00
PHST- 2020/05/19 00:00 [received]
PHST- 2020/07/13 00:00 [revised]
PHST- 2020/07/14 00:00 [accepted]
PHST- 2020/08/11 06:00 [pubmed]
PHST- 2021/04/29 06:00 [medline]
PHST- 2020/08/11 06:00 [entrez]
AID - S0883-5403(20)30793-2 [pii]
AID - 10.1016/j.arth.2020.07.035 [doi]
PST - ppublish
SO  - J Arthroplasty. 2021 Jan;36(1):187-192. doi: 10.1016/j.arth.2020.07.035. Epub 
      2020 Jul 21.