PMID- 32778032 OWN - NLM STAT- MEDLINE DCOM- 20210916 LR - 20221207 IS - 1875-6417 (Electronic) IS - 1573-3998 (Linking) VI - 17 IP - 7 DP - 2021 TI - Mindfulness Practice for Glycemic Control: Could it be a New Strategy for an Old Problem? A Systematic Review and Meta-Analysis. PG - e081020184730 LID - 10.2174/1573399816666200810131055 [doi] AB - BACKGROUND: The management of type 2 diabetes mellitus (T2DM) requires a complex and organized care that includes patient's lifestyle change. Additionally, emotional well-being is an important part of self-management, and it may impair the individual's adherence. Therefore, equipping the patients with the necessary coping and self-care techniques may be an important step in managing diabetes. OBJECTIVE: To evaluate the effect of interventions using established mindfulness-based protocols on glycemic control of individuals with T2DM. METHODS: Data sources: Two electronic databases (PubMed and EMBASE) were searched from inception to December 2019. We limited our search to published studies in English, Spanish and Portuguese languages. STUDY SELECTION: Randomized clinical trials that assessed the effects of mindfulness in individuals with T2DM were selected. DATA EXTRACTION: Two authors independently assessed the risk of bias and extracted data from the included trials. Data were pooled using inverse-variance random-effects meta-analyses. The quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. RESULTS: Four randomized trials were included. There were no differences in blood glucose change (mean difference between groups (MD) -0.73mg/dl; 95% CI, -10.49; 9.02; I2 =0%; very low quality of evidence) or glycated hemoglobin (MD 0.05%; 95%CI -0.22 to 0.32; I2 =29%; very low quality of evidence). CONCLUSION: Although the quality of current evidence is very low, our findings suggest that established protocols involving mindfulness have no effect on blood glucose or glycated hemoglobin in individuals with T2DM. Indeed, large-scale trials are needed to evaluate the contribution of mindfulness to glycemic control in clinical practice. PROSPERO Registration ID: RD42020161940. CI - Copyright(c) Bentham Science Publishers; For any queries, please email at epub@benthamscience.net. FAU - Bersch-Ferreira, Angela Cristine AU - Bersch-Ferreira AC AD - HCor Research Institute (IP-HCor), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - Weber, Bernardete AU - Weber B AD - HCor Research Institute (IP-HCor), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - da Silva, Joao Gabriel Sanchez Tavares AU - da Silva JGST AD - Health Knowledge Implementation Laboratory (LICS), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - Pagano, Raira AU - Pagano R AD - Health Knowledge Implementation Laboratory (LICS), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - Figueiro, Mabel Fernandes AU - Figueiro MF AD - Health Knowledge Implementation Laboratory (LICS), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - da Silva, Lucas Ribeiro AU - da Silva LR AD - HCor Research Institute (IP-HCor), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - de Souza Mota, Luis Gustavo AU - de Souza Mota LG AD - Health Knowledge Implementation Laboratory (LICS), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - Suzumura, Erica Aranha AU - Suzumura EA AD - Preventive Medicine Department, Faculdade de Medicina da Universidade de Sao Paulo (FMUSP), Sao Paulo, Brazil. FAU - Torreglosa, Camila Ragne AU - Torreglosa CR AD - HCor Research Institute (IP-HCor), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - de Sousa Lara, Enilda AU - de Sousa Lara E AD - Health Knowledge Implementation Laboratory (LICS), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - Quinhoneiro, Driele AU - Quinhoneiro D AD - Department of Psychiatric Nursing and Human Science, Ribeirao Preto College of Nursing, Universidade de Sao Paulo, Ribeirao Preto, Brazil. FAU - da Silva Gherardi-Donato, Edilaine Cristina AU - da Silva Gherardi-Donato EC AD - Department of Psychiatric Nursing and Human Science, Ribeirao Preto College of Nursing, Universidade de Sao Paulo, Ribeirao Preto, Brazil. FAU - Bueno, Priscila Regina Torres AU - Bueno PRT AD - HCor Research Institute (IP-HCor), Hospital do Coracao (HCor), Sao Paulo, Brazil. FAU - Marcadenti, Aline AU - Marcadenti A AD - HCor Research Institute (IP-HCor), Hospital do Coracao (HCor), Sao Paulo, Brazil. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review PL - United Arab Emirates TA - Curr Diabetes Rev JT - Current diabetes reviews JID - 101253260 RN - 0 (Blood Glucose) RN - 0 (Glycated Hemoglobin A) SB - IM MH - Blood Glucose MH - *Diabetes Mellitus, Type 2/therapy MH - Glycated Hemoglobin MH - Humans MH - *Mindfulness MH - *Randomized Controlled Trials as Topic MH - *Self-Management OTO - NOTNLM OT - Mindfulness OT - blood glucose OT - diabetes mellitus OT - glycated hemoglobin OT - meta-analysis. OT - systematic review OT - type 2 EDAT- 2020/08/12 06:00 MHDA- 2021/09/18 06:00 CRDT- 2020/08/12 06:00 PHST- 2020/05/10 00:00 [received] PHST- 2020/07/03 00:00 [revised] PHST- 2020/07/09 00:00 [accepted] PHST- 2020/08/12 06:00 [pubmed] PHST- 2021/09/18 06:00 [medline] PHST- 2020/08/12 06:00 [entrez] AID - CDR-EPUB-108999 [pii] AID - 10.2174/1573399816666200810131055 [doi] PST - ppublish SO - Curr Diabetes Rev. 2021;17(7):e081020184730. doi: 10.2174/1573399816666200810131055.