PMID- 32778443 OWN - NLM STAT- MEDLINE DCOM- 20211124 LR - 20240426 IS - 1943-4693 (Electronic) IS - 0027-9684 (Print) IS - 0027-9684 (Linking) VI - 113 IP - 3 DP - 2021 Jun TI - Are There Regional Differences in Triple Negative Breast Cancer among Non-Hispanic Black Women? PG - 353-356 LID - S0027-9684(17)30188-8 [pii] LID - 10.1016/j.jnma.2020.07.016 [doi] AB - BACKGROUND: Non-Hispanic black women (NHB) are diagnosed with triple negative breast cancer (TNBC) more often than other ethnic or racial groups in the United States (US). This study describes regional differences in TNBC incidence among NHB women in the US from 2011 to 2015. METHODS: We analyzed data from the United States Cancer Statistics (USCS) that includes incidence data from the Centers for Disease Control and Prevention's National Program of Cancer Registries (NPCR) and the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) programs. RESULTS: Compared to the incidence rate for NHB women in the South, rates were significantly lower in the Northeast (22.6 per 100,000), higher in the Midwest (25.5 per 100,000) and similar in the West. These regional differences might be explained by genetic admixture among people with different geographic ancestral origins. CONCLUSIONS: Results from this study highlight the need to extend etiological research and evidence-based cancer prevention and control efforts to women at high risk of this disease in order to decrease cancer disparities. CI - Published by Elsevier Inc. FAU - Bartley, Shelton J AU - Bartley SJ AD - Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA. FAU - Wu, Manxia AU - Wu M AD - Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA. FAU - Benard, Vicki AU - Benard V AD - Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA. FAU - Ambrosone, Christine AU - Ambrosone C AD - Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY, USA. FAU - Richardson, Lisa C AU - Richardson LC AD - Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: lfr8@cdc.gov. LA - eng GR - CC999999/ImCDC/Intramural CDC HHS/United States PT - Journal Article DEP - 20200807 PL - United States TA - J Natl Med Assoc JT - Journal of the National Medical Association JID - 7503090 SB - IM MH - *Black or African American MH - *Breast Neoplasms/ethnology/genetics MH - Female MH - Humans MH - Incidence MH - *Triple Negative Breast Neoplasms/ethnology/genetics MH - United States/epidemiology PMC - PMC11034727 MID - NIHMS1675503 OTO - NOTNLM OT - Cancer biomarkers OT - Estrogen receptors OT - HER2Neu OT - Non-Hispanic black women OT - Progesterone receptors OT - Triple negative breast cancer COIS- Competing Interests: The authors declare that they have no competing interests. EDAT- 2020/08/12 06:00 MHDA- 2021/11/25 06:00 PMCR- 2024/04/22 CRDT- 2020/08/12 06:00 PHST- 2017/08/07 00:00 [received] PHST- 2019/03/28 00:00 [revised] PHST- 2020/08/12 06:00 [pubmed] PHST- 2021/11/25 06:00 [medline] PHST- 2020/08/12 06:00 [entrez] PHST- 2024/04/22 00:00 [pmc-release] AID - S0027-9684(17)30188-8 [pii] AID - 10.1016/j.jnma.2020.07.016 [doi] PST - ppublish SO - J Natl Med Assoc. 2021 Jun;113(3):353-356. doi: 10.1016/j.jnma.2020.07.016. Epub 2020 Aug 7.