PMID- 32780561
OWN - NLM
STAT- MEDLINE
DCOM- 20210819
LR  - 20210819
IS  - 1463-1318 (Electronic)
IS  - 1462-8910 (Linking)
VI  - 22
IP  - 12
DP  - 2020 Dec
TI  - A prospective evaluation of the outcome of submucosal ligation of fistula tract.
PG  - 2199-2203
LID - 10.1111/codi.15305 [doi]
AB  - AIM: Fistula-in-ano (FIA) is an anomalous passage between perianal skin and the 
      anal canal or the rectum that presents many management difficulties. Ligation of 
      intersphincteric fistula tract (LIFT) was introduced as a cost-effective 
      sphincter-saving procedure with a reported success rate of 94.4%. Unfortunately, 
      this procedure is technically challenging, and recently submucosal ligation of 
      fistula tract (SLOFT), a simplification of LIFT, was proposed. Our aim was to 
      assess the SLOFT technique over a longer follow-up period to determine its 
      effectiveness. METHOD: A prospective observational study was performed in 47 
      patients with FIA treated by SLOFT from September 2017 to February 2019. RESULTS: 
      There were 47 patients, of whom 33(70.2%) were men. The median age was 39 years 
      (range 30-50 years). All the patients had primary FIA of cryptoglandular origin. 
      The patients were followed up for 1 year and were postoperatively assessed at 2, 
      4, 12 and 24 weeks and 1 year. The median body mass index was 27.3 kg/m(2) (range 
      24.3-29.4 kg/m(2) ) and the median duration of surgery was 15 min (range 
      13-20 min). Most (83.0%) of the fistulas were trans-sphincteric. The success 
      rates at the end of 24 weeks and 1 year were 87.2% and 80.9%, respectively. No 
      postoperative incontinence was recorded. CONCLUSION: In our series the success 
      rate of SLOFT was 80.9%. There were no sphincter-related complications. Repeat 
      SLOFT was feasible for cases of recurrence. Therefore, SLOFT should be considered 
      an alternative sphincter-saving procedure to LIFT for the management of FIA.
CI  - (c) 2020 The Association of Coloproctology of Great Britain and Ireland.
FAU - Raja Ram, N K
AU  - Raja Ram NK
AUID- ORCID: 0000-0001-8604-8918
AD  - National University of Malaysia Medical Centre, Kuala Lumpur, Malaysia.
AD  - Sultanah Aminah Hospital, Johor Bahru, Malaysia.
FAU - Chan, K K
AU  - Chan KK
AD  - Sultanah Aminah Hospital, Johor Bahru, Malaysia.
FAU - Md Nor, S F
AU  - Md Nor SF
AD  - Sultanah Aminah Hospital, Johor Bahru, Malaysia.
FAU - Sagap, I
AU  - Sagap I
AD  - National University of Malaysia Medical Centre, Kuala Lumpur, Malaysia.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20201006
PL  - England
TA  - Colorectal Dis
JT  - Colorectal disease : the official journal of the Association of Coloproctology of 
      Great Britain and Ireland
JID - 100883611
SB  - IM
CIN - Colorectal Dis. 2020 Dec;22(12):2333-2334. PMID: 32896051
CIN - Colorectal Dis. 2020 Dec;22(12):2334-2335. PMID: 32946673
MH  - Adult
MH  - Anal Canal
MH  - Humans
MH  - Ligation
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - *Rectal Fistula/surgery
MH  - Recurrence
MH  - Treatment Outcome
OTO - NOTNLM
OT  - SLOFT
OT  - fistula-in-ano
OT  - sphincter-saving procedure
EDAT- 2020/08/12 06:00
MHDA- 2021/08/20 06:00
CRDT- 2020/08/12 06:00
PHST- 2020/03/29 00:00 [received]
PHST- 2020/08/04 00:00 [accepted]
PHST- 2020/08/12 06:00 [pubmed]
PHST- 2021/08/20 06:00 [medline]
PHST- 2020/08/12 06:00 [entrez]
AID - 10.1111/codi.15305 [doi]
PST - ppublish
SO  - Colorectal Dis. 2020 Dec;22(12):2199-2203. doi: 10.1111/codi.15305. Epub 2020 Oct 
      6.