PMID- 32781483
OWN - NLM
STAT- MEDLINE
DCOM- 20210818
LR  - 20210818
IS  - 1752-699X (Electronic)
IS  - 1752-6981 (Linking)
VI  - 14
IP  - 12
DP  - 2020 Dec
TI  - Impact of diabetes mellitus on the risk of severe exacerbation in patients with 
      chronic obstructive pulmonary disease.
PG  - 1208-1211
LID - 10.1111/crj.13255 [doi]
AB  - INTRODUCTION: Suffering type 2 diabetes mellitus (T2DM) appears to promote the 
      occurrence of respiratory infections. However, studies to evaluate the risk of 
      hospital admission due to exacerbations in patients with chronic obstructive 
      pulmonary disease (COPD) and concomitant T2DM are scarce. MATERIALS AND METHODS: 
      Prospective, observational study with a maximum follow-up of 18 months. 
      Information on lung function, body mass index, degree of dyspnea, number of 
      exacerbations, comorbidities and pneumococcal vaccination was obtained. Patients 
      were classified into the categories COPD with (COPD/+T2DM) and without T2DM 
      (COPD/-T2DM). RESULTS: A total of 121 patients with COPD were enrolled. 
      Forty-seven (38%) of the study participants were diabetic. The presence of T2DM 
      increased the risk of hospital admission due to COPD exacerbation (OR 2.66; 
      P = 0.031), but no significant difference in the total number of exacerbations 
      was detected. CONCLUSIONS: The risk of hospital admission in the course of 
      exacerbation seems to be higher in COPD/+T2DM patients than in COPD/-T2DM 
      subjects.
CI  - (c) 2020 John Wiley & Sons Ltd.
FAU - Figueira Goncalves, Juan Marco
AU  - Figueira Goncalves JM
AD  - Pneumology and Thoracic Surgery Service, University Hospital Nuestra Senora de la 
      Candelaria (HUNSC), Santa Cruz de Tenerife, Spain.
FAU - Garcia Bello, Miguel Angel
AU  - Garcia Bello MA
AD  - Division of Clinical Epidemiology and Biostatistics, Research Unit, University 
      Hospital Nuestra Senora de la Candelaria (HUNSC) and Primary Care Management, 
      Santa Cruz de Tenerife, Spain.
FAU - Golpe, Rafael
AU  - Golpe R
AUID- ORCID: 0000-0002-3759-5322
AD  - Respiratory Medicine Service, University Hospital Lucus Augusti, Lugo, Spain.
FAU - Alonso Jerez, Juan Luis
AU  - Alonso Jerez JL
AD  - General Practice, C.S Tejina, Servicio Canario de Salud, Santa Cruz de Tenerife, 
      Spain.
FAU - Garcia-Talavera, Ignacio
AU  - Garcia-Talavera I
AD  - Pneumology and Thoracic Surgery Service, University Hospital Nuestra Senora de la 
      Candelaria (HUNSC), Santa Cruz de Tenerife, Spain.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20200907
PL  - England
TA  - Clin Respir J
JT  - The clinical respiratory journal
JID - 101315570
SB  - IM
MH  - Comorbidity
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology
MH  - Disease Progression
MH  - Humans
MH  - Prospective Studies
MH  - *Pulmonary Disease, Chronic Obstructive/complications/epidemiology
OTO - NOTNLM
OT  - chronic obstructive pulmonary disease
OT  - diabetes mellitus
OT  - exacerbation
EDAT- 2020/08/12 06:00
MHDA- 2021/08/19 06:00
CRDT- 2020/08/12 06:00
PHST- 2020/04/18 00:00 [received]
PHST- 2020/08/06 00:00 [accepted]
PHST- 2020/08/12 06:00 [pubmed]
PHST- 2021/08/19 06:00 [medline]
PHST- 2020/08/12 06:00 [entrez]
AID - 10.1111/crj.13255 [doi]
PST - ppublish
SO  - Clin Respir J. 2020 Dec;14(12):1208-1211. doi: 10.1111/crj.13255. Epub 2020 Sep 
      7.