PMID- 32791655 OWN - NLM STAT- MEDLINE DCOM- 20200821 LR - 20240109 IS - 1536-5964 (Electronic) IS - 0025-7974 (Print) IS - 0025-7974 (Linking) VI - 99 IP - 30 DP - 2020 Jul 24 TI - The efficacy and safety of Banxia-Houpo-Tang for chronic pharyngitis: A protocol for systematic review and meta analysis. PG - e19922 LID - 10.1097/MD.0000000000019922 [doi] LID - e19922 AB - BACKGROUND: Chronic pharyngitis is a common disease with a dry throat, sore throat, pharyngeal itching, dry cough, and difficulty in swallowing, bringing inconvenience to patients' daily life. Banxia-Houpo-Tang (BHT) has proven to be effective in the treatment of chronic pharyngitis, yet its real extent is not well understood. To prove this point, we will perform a protocol for a systematic review and meta-analysis of BHT for chronic pharyngitis. METHODS/DESIGN: We will search for electronic databases both English and Chinese from inception to December 2019. Two experienced researchers select the qualified articles from: The Cochrane Library, EBM Reviews, OVID, Web of Science, PubMed, Chinese National Knowledge Infrastructure (CNKI), China Academic Journal Network Publishing Database (CAJD), China Biomedical Literature database (CBM), VIP Database for Chinese Technical Periodicals (VIP). Journal Integration Platform and WAN FANG Database. We select the appropriate searching language. The primary outcome was remission rate, and the secondary outcomes include clinical symptoms, clinical examination, adverse event. Data extraction and quality assessment will be conducted by 2 experienced researchers independently. Data analysis and the risk of bias assessment will be determined by RevMan 5.3 software. RESULTS: Based on the current proofs, we will get the exact evidence about the safety and effectiveness of BHT in the treatment of chronic pharyngitis. CONCLUSION: Our study is the first meta-analysis to evaluate the efficacy and safety of BHT in the treatment of chronic pharyngitis, and it will provide evidence for alternative treatment for the management of chronic pharyngitis. OSF REGISTRATION NUMBER: DOI 10.17605/OSF.IO/QNF6X. FAU - Xu, Chenyi AU - Xu C AD - Hospital of Chengdu University of Traditional Chinese Medicine. FAU - Yue, Rensong AU - Yue R AUID- ORCID: 0000-0002-4417-3312 AD - Hospital of Chengdu University of Traditional Chinese Medicine. FAU - Lv, Xuelian AU - Lv X AD - Hospital of Traditional Chinese Medicine of Xinjin, Chengdu, P.R. China. FAU - Wu, Tingchao AU - Wu T AD - Hospital of Chengdu University of Traditional Chinese Medicine. FAU - Yang, Maoyi AU - Yang M AD - Hospital of Chengdu University of Traditional Chinese Medicine. FAU - Chen, Yuan AU - Chen Y AD - Hospital of Chengdu University of Traditional Chinese Medicine. LA - eng PT - Journal Article PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R RN - 0 (Banxia Houpo Tang) RN - 0 (Drugs, Chinese Herbal) SB - IM MH - Chronic Disease MH - Drugs, Chinese Herbal/*therapeutic use MH - Zingiber officinale MH - Humans MH - Magnolia MH - Meta-Analysis as Topic MH - Perilla MH - Pharyngitis/*drug therapy MH - Phytotherapy MH - Pinellia MH - Systematic Reviews as Topic MH - Wolfiporia PMC - PMC7387004 COIS- The authors declare no competing interests. The authors have no conflicts of interest to disclose. EDAT- 2020/08/15 06:00 MHDA- 2020/08/22 06:00 PMCR- 2020/07/24 CRDT- 2020/08/15 06:00 PHST- 2020/08/15 06:00 [entrez] PHST- 2020/08/15 06:00 [pubmed] PHST- 2020/08/22 06:00 [medline] PHST- 2020/07/24 00:00 [pmc-release] AID - 00005792-202007240-00001 [pii] AID - MD-D-20-02223 [pii] AID - 10.1097/MD.0000000000019922 [doi] PST - ppublish SO - Medicine (Baltimore). 2020 Jul 24;99(30):e19922. doi: 10.1097/MD.0000000000019922.