PMID- 32797858 OWN - NLM STAT- MEDLINE DCOM- 20201006 LR - 20221207 IS - 1873-3778 (Electronic) IS - 0021-9673 (Linking) VI - 1626 DP - 2020 Aug 30 TI - Microcrystalline cellulose/metal-organic framework hybrid as a sorbent for dispersive micro-solid phase extraction of chlorophenols in water samples. PG - 461386 LID - S0021-9673(20)30662-2 [pii] LID - 10.1016/j.chroma.2020.461386 [doi] AB - In this study, the microcrystalline cellulose/metal-organic framework 199 hybrid (MCC/MOF-199) was applied as sorbent for the dispersive micro-solid phase-extraction (D-muSPE) of chlorophenols. The D-muSPE method combined with high-performance liquid chromatography- ultraviolet detection (HPLC-UV) was employed to determine of four chlorophenols including 2-chlorophenol (2-CP), 4-chlorophenol (4-CP), 2,3-dichlorophenol (2,3-DCP), and 2,5-dichlorophenol (2,5-DCP) in aqueous. The main parameters of the D-muSPE process that influence the extraction (i.e. the amount of sorbent, elution condition, extraction time, and pH) were investigated and optimized. Based on the outputs, the presence of MCC on the surface of MOF-199 leads to improve the properties of MOF-199 and the MCC/MOF-199 has the highest sorption capacity, durability, and porosity in comparison with MCC and MOF-199. According to the validation study at the optimized conditions, the linearity for the analytes was achieved in the range from 0.1 to 200 ng mL(-1) for 2-CP and 4-CP and 0.15 to 200 ng mL(-1) for 2,3-DCP and 2,5-DCP with correlation coefficients between 0.9928 and 0.9965. The limits of detection calculated at S/N=3 were in the range of 0.03-0.05 ng mL(-1). Besides, the relative standard deviations (RSDs) for three spiking levels (0.2, 10,100 ng mL(-1)) do not exceed 6.8% and extraction recoveries are between 81.0% and 88.3%. Finally, the D-muSPE-HPLC-UV method was successfully applied to the analysis of CPs in real water samples (mineral, river and wastewater samples) with good recoveries (95.8 to 99.5%) and satisfactory precisions (RSD < 6.8%). CI - Copyright (c) 2020. Published by Elsevier B.V. FAU - Ghaemi, Ferial AU - Ghaemi F AD - Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia (UKM), 43600, Bangi, Selangor, Malaysia. FAU - Amiri, Amirhassan AU - Amiri A AD - Department of Chemistry, Faculty of Sciences, Hakim Sabzevari University, 96179-76487 Sabzevar, Iran. Electronic address: Ah.amiri@hsu.ac.ir. LA - eng PT - Journal Article DEP - 20200703 PL - Netherlands TA - J Chromatogr A JT - Journal of chromatography. A JID - 9318488 RN - 0 (Chlorophenols) RN - 0 (Metal-Organic Frameworks) RN - 0 (Waste Water) RN - 9004-34-6 (Cellulose) RN - OP1R32D61U (microcrystalline cellulose) SB - IM MH - Cellulose/*chemistry MH - Chlorophenols/*analysis/chemistry/isolation & purification MH - Chromatography, High Pressure Liquid/methods MH - Fresh Water/analysis MH - Hydrogen-Ion Concentration MH - Limit of Detection MH - Metal-Organic Frameworks/*chemistry MH - Rivers/chemistry MH - Solid Phase Microextraction/*methods MH - Spectrophotometry, Ultraviolet MH - Wastewater/analysis OTO - NOTNLM OT - Chlorophenols: Dispersive micro-solid-phase extraction OT - HPLC-UV OT - Metal-organic framework 199 OT - Microcrystal cellulose OT - Water samples COIS- Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2020/08/17 06:00 MHDA- 2020/10/07 06:00 CRDT- 2020/08/17 06:00 PHST- 2020/05/04 00:00 [received] PHST- 2020/06/27 00:00 [revised] PHST- 2020/06/30 00:00 [accepted] PHST- 2020/08/17 06:00 [entrez] PHST- 2020/08/17 06:00 [pubmed] PHST- 2020/10/07 06:00 [medline] AID - S0021-9673(20)30662-2 [pii] AID - 10.1016/j.chroma.2020.461386 [doi] PST - ppublish SO - J Chromatogr A. 2020 Aug 30;1626:461386. doi: 10.1016/j.chroma.2020.461386. Epub 2020 Jul 3.